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COL18A1 encodes the alpha chain of type XVIII collagen. Zusätzlich bieten wir Ihnen COL18A1 Kits (76) und COL18A1 Proteine (20) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal COL18A1 Primary Antibody für IF (p), IHC (p) - ABIN669951
Gao, Zhao, Liang, Li, Cao, Liu: Effect of peritoneal dialysis on expression of vascular endothelial growth factor, basic fibroblast growth factor and endostatin of the peritoneum in peritoneal dialysis patients. in Nephrology (Carlton, Vic.) 2011
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Human Monoclonal COL18A1 Primary Antibody für IHC (p), WB - ABIN448134
Chen, Hsu, Song, Huang, Tsai, Kuo, Hsu, Tsai, Tsai, Woung, Chiou, Lu, Chen: Celecoxib enhances radiosensitivity in medulloblastoma-derived CD133-positive cells. in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2010
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Human Monoclonal COL18A1 Primary Antibody für IA, IHC (fro) - ABIN2192047
Deininger, Fimmen, Kremsner, Meyermann, Schluesener: Accumulation of endostatin/collagenXVIII in brains of patients who died with cerebral malaria. in Journal of neuroimmunology 2002
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Chicken Monoclonal COL18A1 Primary Antibody für ELISA, WB - ABIN265797
Jung, Lim: The antiangiogenic and antinociceptive activities of n-propyl gallate. in Phytotherapy research : PTR 2011
Structural and biological functions of COL18A1, such as its requirement in the maintenance of basement membrane integrity and its emerging roles in regulating cell survival, stem or progenitor cell maintenance and differentiation and inflammation have been reported. (Review)
Lower endostatin levels or a predominance of VEGF (zeige VEGFA Antikörper) over endostatin are predictors of poor short-term prognosis of intracranial atherosclerotic stenosis.
We further show that the SAGA deubiquitinase-activated gene Multiplexin (Mp) is required in glia for proper photoreceptor axon targeting. Mutations in the human ortholog of Mp, COL18A1, have been identified in a family with a SCA7-like progressive visual disorder, suggesting that defects in the expression of this gene in SCA7 patients could play a role in the retinal degeneration that is unique to this ataxia.
Two COL18A1 variants co-segregated with familial epilepsy and anterior polymicrogyria in a family.
Blood endostatin wasdddddddddddddddddddddddddf significantly higher in chronic hepatitis C patients with liver fibrosis compared to those without fibrosis.
The homozygous DN and NN genotypes of COL18A1 D104N were associated with the risk of osteosarcoma.
Endostatin is increased in patients with primary sjogren's syndrome patients with interstitial lung disease.
Data show that endostatin levels were elevated in patients with systemic sclerosis (SSc (zeige CYP11A1 Antikörper)) and mixed connective tissue disease (MCTD).
Collaterals formation seems to be associated with the activation of pro-inflammatory factors, growth factors and endostatin in chronic heart failure.
Genebased analyses revealed associations of the COL18A1 gene with longitudinal Blood Pressure phenotypes, associations with essential hypertension, Blood Pressure salt sensitivity, preeclampsia, or preclinical stages of atherosclerosis.
Together these data suggest that Lh3 (zeige PLOD3 Antikörper)-Collagen18A1 dependent ECM (zeige MMRN1 Antikörper) modifications regulate the transition of trunk neural crest cells from a non-segmental sheet like migration mode to a segmental stream migration mode
These results provide important insight into the biological function and regulation of COL18A1, and point to additional sequences that may contribute to complex diseases involving COL18A1.
diwanka (lh3 (zeige PLOD3 Antikörper)) acts through myotomal type XVIII collagen, a ligand for neural-receptor protein tyrosine phosphatases that guide motor axons
Investigate the timecourse of collagen XVIII processing with release of endostatin (ES) and other low-molecular-weight fragments during early ischemia-reperfusion of the heart.
This study examined the staining levels of proteasomal and autophagy markers in the RPE (zeige RPE Antikörper) of different ages of the Col18a1 (-/-) mice. Eyes from 3, 6-7, 10-13 and 18 months old mice were enucleated and embedded in paraffin according to the routine protocol.
Kidney fibrosis in aging may represent a natural outcome of upregulated endostatin (EST (zeige MAP3K8 Antikörper)) and transglutaminase 2 (TG2 (zeige TGM2 Antikörper)), but more likely it appears to be a result of cumulative stresses occurring on the background of synergistically acting geronic (aging) proteins, EST (zeige MAP3K8 Antikörper) and TG2 (zeige TGM2 Antikörper).
There are correlations between the elevation of endostatin levels and parallel microvascular rarefaction and induction of renal fibrosis in aging mice.
An excess of the collagen XVIII Tsp-1 (zeige GZMA Antikörper) domain is deleterious in the eye, possibly by impairing certain functions of the full-length molecule.
The results of the present study indicate endostatin promotes soft callus formation but inhibits callus remodeling during fracture healing most probably by an inhibition of angiogenesis.
Data indicate that delivery by attenuated Salmonella of the combination therapeutic plasmid simultaneously knocked down the expression of Stat3 (zeige STAT3 Antikörper) and resulted in over-expression of Endostatin, which synergistically inhibited prostate cancer growth.
Endostatin lowers blood pressure via nitric oxide and prevents hypertension associated with VEGF inhibition
Women with early-onset, but not late-onset preeclampsia have higher levels of endostatin than healthy pregnant women in corresponding lengths of gestation.
In vivo, Collagen XVIII/endostatin does not play an indispensable role in skeletal development
Lack of collagen XVIII/endostatin results in eye abnormalities.
This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, collagen alpha-1(XVIII) chain
, multi-functional protein MFP
, procollagen, type XVIII, alpha 1
, collagen, type XVIII, alpha 1
, alpha 1 type XVIII collagen
, collagen alpha-1(XVIII) chain-like
, LOW QUALITY PROTEIN: collagen alpha-1(XVIII) chain