anti-Collagen, Type VIII, alpha 1 (COL8A1) Antikörper

COL8A1 encodes one of the two alpha chains of type VIII collagen. Zusätzlich bieten wir Ihnen COL8A1 Kits (25) und COL8A1 Proteine (12) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
COL8A1 12837 Q00780
COL8A1 304021  
COL8A1 1295 P27658
Direkt bei antikoerper-online bestellen
  • +49 (0)241 95 163 153
  • +49 (0)241 95 163 155
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-COL8A1 Antikörper auf antikoerper-online.de

Showing 10 out of 57 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB Western blot analysis of Collagen 8 alpha 1 expression in MDA-MB453 (A), A549 (B), SP2/0 (C), PC12 (D) whole cell lysates. 200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: Collagen VIII alpha 1 Antibody [NBP2-13856] - Staining of human soft tissue shows distinct positivity in internal elastic lamina of the blood vessel. Immunocytochemistry/Immunofluorescence: Collagen VIII alpha 1 Antibody [NBP2-13856] - Staining of human cell line HeLa shows positivity in vesicles. Antibody staining is shown in green. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert WB COL8A1 Antibody (N-term)  western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the COL8A1 antibody detected the COL8A1 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Kaninchen Meerschweinchen Unkonjugiert ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 15 Tage
361,90 €
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 11 bis 14 Tage
565,71 €
Details
Human Kaninchen Unkonjugiert ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
941,11 €
Details
Kaninchen Maus Unkonjugiert ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 15 Tage
266,67 €
Details
Human Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 11 bis 15 Tage
333,33 €
Details
Maus Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
342,86 €
Details
Ratte Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
361,90 €
Details

COL8A1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine) ,


,
Rat (Rattus)


,
Human , ,
,

, , , , ,

Am meisten referenzierte anti-COL8A1 Antikörper

  1. Human Polyclonal COL8A1 Primary Antibody für IHC - ABIN965914 : Muragaki, Mattei, Yamaguchi, Olsen, Ninomiya: The complete primary structure of the human alpha 1 (VIII) chain and assignment of its gene (COL8A1) to chromosome 3. in European journal of biochemistry / FEBS 1991 (PubMed)
    Show all 9 Pubmed References

Weitere Antikörper gegen COL8A1 Interaktionspartner

Mouse (Murine) Collagen, Type VIII, alpha 1 (COL8A1) Interaktionspartner

  1. Lack of collagen VIII (zeige COX8A Antikörper) reduces myofibroblast differentiation and fibrosis and promotes early mortality and left ventricle dilatation in response to pressure overload in mice.

  2. Type VIII (zeige COX8A Antikörper) collagen signals via beta1 integrin and RhoA (zeige RHOA Antikörper) to regulate MMP-2 (zeige MMP2 Antikörper) expression and smooth muscle cell migration.

  3. Type VIII (zeige COX8A Antikörper) collagen mediates vessel wall remodeling after arterial injury and fibrous cap formation in atherosclerosis.

  4. in contrast to diabetic wild-type mice EMT (zeige ITK Antikörper)-like changes were attenuated in diabetic Col8alpha1/alpha2-KO mice, indicating that collagen VIII (zeige COX8A Antikörper) may be 1 of the major inducers of epithelial-to-mesenchymal transition-like changes in kidneys of diabetic wild-type mice

  5. Type VIII (zeige COX8A Antikörper) collagen significantly modulates the effect of TGF-beta1 (zeige TGFB1 Antikörper) on mesangial cells and may therefore play a role in the pathogenesis of diabetic nephropathy.

  6. Crystal structure of mouse alpha1(VIII (zeige COX8A Antikörper))(3) NC1 domain trimer at 1.9 A resolution. Surface of collagen VIII (zeige COX8A Antikörper) NC1 trimer has three strips of partially exposed aromatic residues, likely involved in supramolecular assemblies.

  7. These data indicate that type VIII (zeige COX8A Antikörper) collagen plays an important role in glial scar formation during the repair process by astrocytes.

  8. Smooth muscle cells can modify the matrix microenvironment by producing type VIII (zeige COX8A Antikörper) collagen, using it to overlay type I collagen, and generating a substrate favorable for migration

  9. Downregulation of COL8A1 expression sensitized hepatocarcinoma cells to the action of D-limonene, impeded cell proliferation, and led to decreased invasiveness, indicating that COL8A1 might serve as a target for gene therapy in hepatocarcinoma.

  10. Oxidized phospholipids induce type VIII (zeige COX8A Antikörper) collagen expression and vascular smooth muscle cell migration.

Human Collagen, Type VIII, alpha 1 (COL8A1) Interaktionspartner

  1. High COL8A1 level is associated with chronic obstructive pulmonary disease and cancer.

  2. The COL8A1 rs13095226 polymorphism is not associated with nAMD or PCV, which suggesting this gene maybe not a susceptibility gene locus for neovascular age-related macular degeneration (nAMD) or polypoidal choroidal vasculopathy (PCV) in Chinese subjects.

  3. High COL8A1 expression is associated with early loss of kidney function.

  4. Data indicate that complement factor H (CFH (zeige CFH Antikörper)) R1210C and common variants in COL8A1 and RAD51B (zeige Rad51B Antikörper) plus six genes contribute predictive information for advanced macular degeneration (AMD (zeige AMD1 Antikörper)) beyond macular and behavioral phenotypes.

  5. The results are consistent with the proposal that rare CNVs play a role in TS aetiology and suggest a possible role for rearrangements in the COL8A1 and NRXN1 (zeige NRXN1 Antikörper) gene regions.

  6. In addition, eight genes classified as 'second tier' hits in the original study (PAX7 (zeige PAX7 Antikörper), THADA, COL8A1/FILIP1L (zeige FILIP1L Antikörper), DCAF4L2, GADD45G (zeige GADD45G Antikörper), NTN1 (zeige NTN1 Antikörper), RBFOX3 (zeige RBFOX3 Antikörper) and FOXE1 (zeige FOXE1 Antikörper)) showed evidence of linkage and association in this replication sample.

  7. The purpose of this study is to evaluate COL8A1 and COL8A2 (zeige COL8a2 Antikörper) as candidate genes for thin central corneal thickness in human primary open angle glaucoma patients.

  8. The absence of pathogenic mutations identified in the COL8A1 or COL8A2 (zeige COL8a2 Antikörper) genes in affected members of 15 pedigrees with familial FECD (zeige COL8a2 Antikörper) (Fuchs endothelial corneal dystrophy) indicates that other genetic factors are involved.

  9. The absence of pathogenic mutations in COL8A1 and COL8A2 (zeige COL8a2 Antikörper) in patients with keratoconus indicates that other genetic factors are involved in the pathogenesis of this corneal ectatic disorder.

COL8A1 Antigen-Profil

Protein Überblick

This gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain collagen and a major component of the basement membrane of the corneal endothelium. The type VIII collagen fibril can be either a homo- or a heterotrimer. Alternatively spliced transcript variants encoding the same protein have been observed.

Genbezeichner und Symbole assoziert mit COL8A1

  • collagen, type VIII, alpha 1 (COL8A1) Antikörper
  • collagen, type VIII, alpha 1 (col8a1) Antikörper
  • collagen, type VIII, alpha 1 (Col8a1) Antikörper
  • C3orf7 Antikörper
  • Col8a-1 Antikörper
  • COL8A1 Antikörper

Bezeichner auf Proteinebene für COL8A1

collagen, type VIII, alpha 1 , collagen alpha-1(VIII) chain , procollagen type VIII alpha 1 , procollagen, type VIII, alpha 1 , cell proliferation-inducing protein 41 , collagen VIII, alpha-1 polypeptide , endothelial collagen , smooth muscle cell-expressed and macrophage conditioned medium-induced protein smag-64 , alpha 1 type VIII collagen , collagen VIII , type VIII collagen alpha 1 chain

GENE ID SPEZIES
460550 Pan troglodytes
494652 Xenopus laevis
100017530 Monodelphis domestica
100585226 Nomascus leucogenys
12837 Mus musculus
304021 Rattus norvegicus
1295 Homo sapiens
100009383 Oryctolagus cuniculus
100717829 Cavia porcellus
397430 Sus scrofa
418378 Gallus gallus
487950 Canis lupus familiaris
538564 Bos taurus
Ausgewählte Anbieter für anti-COL8A1 (COL8A1) Antikörper
Haben Sie etwas anderes gesucht?