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Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. Zusätzlich bieten wir Ihnen Collagen, Type VI Antikörper (81) und Collagen, Type VI Kits (18) und viele weitere Produktgruppen zu diesem Protein an.
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CRB1 (zeige CRB1 Proteine) is an efficient catalyst for the reduction of glutathionylated aldehydes derived from lipid peroxidation.
The ability of human carbonyl reductase 1 (zeige CBR1 Proteine) to efficiently catalyze the reduction of glutathionylated aldehydes derived from lipid peroxidation, that in the case of glutathionylated-4-hydroxyalkanals is associated to the ability to oxidize the hemiacetal hydroxyl group
Data suggest that fatty acids and acyl-CoAs bind competitively with respect to substrate binding to carbonyl reductase 1 (CBR1 (zeige CBR1 Proteine)), an enzyme involved in first-pass drug metabolism in intestinal mucosa; inhibition of CBR1 (zeige CBR1 Proteine) by these products of digestion may lead to food-drug interactions.
AKR1C3 (zeige AKR1C3 Proteine) is the primary enzyme and CBR1 (zeige CBR1 Proteine) is a minor enzyme responsible for warfarin reduction in human liver cytosol.
These results suggest that CR1 induces apoptosis by activating the caspase (zeige CASP3 Proteine) pathway via binding to TNFR1 (zeige TNFRSF1A Proteine).
Critical insights into the substrate selectivity of hCBR1 (zeige CBR1 Proteine) and the interaction between hCBR1 (zeige CBR1 Proteine) and glutathione.
Up-Regulation of Carbonyl Reductase 1 (zeige CBR1 Proteine) Renders Development of Doxorubicin Resistance in Human Gastrointestinal Cancers
CBR1 (zeige CBR1 Proteine) decreases promoted tumor proliferation and growth as well as invasion and metastasis; CBR1 (zeige CBR1 Proteine) has potential to become a new candidate for molecular targeting therapy.
Inhibition of CBR1 (zeige CBR1 Proteine) may increase the efficacy of daunorubicin in cancer tissue.
Protein products of AKR1C1 (zeige DDH Proteine), AKR1C2 (zeige AKR1C2 Proteine), AKR7A3 (zeige AKR7A3 Proteine), CYP3A4 (zeige CYP3A4 Proteine), and carbonyl reductase (CBR1 (zeige CBR1 Proteine)) were found in tumors and those of AKR1C1 (zeige DDH Proteine), AKR7A3 (zeige AKR7A3 Proteine), and CBR1 (zeige CBR1 Proteine) correlated with their transcript levels.
Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q.
, NADPH-dependent carbonyl reductase 1
, carbonyl reductase (NADPH) 1
, carbonyl reductase [NADPH] 1
, prostaglandin 9-ketoreductase
, prostaglandin-E(2) 9-reductase
, short chain dehydrogenase/reductase family 21C, member 1