anti-Collagen, Type VI, alpha 2 (COL6A2) Antikörper

COL6A2 encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. Zusätzlich bieten wir Ihnen Collagen, Type VI, alpha 2 Kits (5) und Collagen, Type VI, alpha 2 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
COL6A2 1292 P12110
COL6A2 12834 Q02788
COL6A2 361821  
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Top anti-Collagen, Type VI, alpha 2 Antikörper auf antikoerper-online.de

Showing 10 out of 58 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, WB <span>COL6A2 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35µg/lane).This demonstrates the COL6A2 antibody detected the COL6A2 protein (arrow).</span> 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-COL6A2 Antibody Titration: </b>1.25ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert IC, IF, IP, IHC, WB Immunofluorescent analysis of Collagen 6 alpha 2 staining in HT29 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Collagen 6 alpha 2 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry: Collagen VI alpha 2 Antibody [NBP1-90951] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue.Lane 6: Human tonsil tissue Immunohistochemistry-Paraffin: Collagen VI alpha 2 Antibody [NBP1-90951] - Staining of human stomach shows strong cytoplasmic positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from K562/A549/HT-29/COS7 cells, using Collagen VI alpha2 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Collagen VI alpha2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Pferd Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Human Kaninchen Unkonjugiert WB Western Blot: Collagen VI alpha 2 Antibody [NBP1-54614] - HepG2 cell lysate, concentration 1.25ug/ml. 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$444.19
Details
Human Kaninchen Unkonjugiert IHC (p), ELISA, WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$478.50
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Human Kaninchen Unkonjugiert WB COL6A2 Antibody (C-term)  western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the COL6A2 antibody detected the COL6A2 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details

COL6A2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human
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Mouse (Murine)


Rat (Rattus)


Am meisten referenzierte anti-Collagen, Type VI, alpha 2 Antikörper

  1. Human Polyclonal COL6A2 Primary Antibody für IHC, IHC (p) - ABIN4299696 : Liu, Carson-Walter, Cooper, Winans, Johnson, Walter: Vascular gene expression patterns are conserved in primary and metastatic brain tumors. in Journal of neuro-oncology 2010 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Collagen, Type VI, alpha 2 Interaktionspartner

Human Collagen, Type VI, alpha 2 (COL6A2) Interaktionspartner

  1. Genetic study showed a missense mutation in COL6A2 (c.820 G>A, p.Gly268Ser) that causes a glycine substitution in the Gly-X-Y collagenous motif, at the beginning of the collagenous triple helical domain. The c.820 G>A mutation segregated in all the affected patients.

  2. Parental mosaicism was confirmed in the four families through quantitative analysis of the ratio of mutant versus wild-type allele (COL6A1 (zeige COL6A1 Antikörper), COL6A2, and COL6A3 (zeige COL6a3 Antikörper)) in genomic DNA from various tissues; consistent with somatic mosaicism, parental samples had lower ratios of mutant versus wild-type allele compared with the fully heterozygote offspring.

  3. Mutations in COL6A2 gene are associated with aberrant mitochondria in Bethlem myopathy.

  4. In UCMD, 8 mutations were identified in COL6A2 in Chinese patients.

  5. Mutations in each of the three collagen VI genes, COL6A1 (zeige COL6A1 Antikörper), COL6A2 and COL6A3 (zeige COL6a3 Antikörper), cause four types of muscle disorders: Ullrich congenital muscular dystrophy, Bethlem myopathy, limb-girdle muscular dystrophy, and autosomal recessive myosclerosis. (Review)

  6. COL6A2 is overexpressed in Down syndrome-affected umbilical cords at early and term gestational ages.

  7. Homozygous COL6A2 mutation, p.Asp215Asn, was identified in both affected siblings. We conclude that the COL6A2 p.Asp215Asn mutation is likely to be responsible for PME (zeige CSTB Antikörper) (Progressive Myoclonus Epilepsy) in this family.

  8. A deletion within intron 1A of the COL6A2 gene, occurring in compound heterozygosity with a small deletion in exon 28, was identified in a BM patient.

  9. the C2A splice variant has a role in recessive COL6A2 C-globular missense mutations in Ullrich congenital muscular dystrophy

  10. The alpha2(VI) chain modulates matrix-metalloproteinase (MMP) availability by sequestering proMMPs in the extracellular matrix, blocking proteolytic activity.

Mouse (Murine) Collagen, Type VI, alpha 2 (COL6A2) Interaktionspartner

  1. gamma-sarcoglycan (zeige SGCG Antikörper)-null/Col6a2Deltaex5 (Col6a2 deficient) mice exhibit reduced muscle pathology compared with gamma-sarcoglycan (zeige SGCG Antikörper)-null mice. Specifically, fewer muscle fibers are degenerating, fiber size varies less. Surprisingly, in spite of this reduction in muscle pathology, muscle function is not significantly improved.

Collagen, Type VI, alpha 2 (COL6A2) Antigen-Profil

Protein Überblick

This gene encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene.

Genbezeichner und Symbole assoziert mit COL6A2

  • collagen type VI alpha 2 chain (COL6A2) Antikörper
  • collagen, type VI, alpha 2 (col6a2) Antikörper
  • collagen, type VI, alpha 2 (Tcur_3411) Antikörper
  • collagen, type VI, alpha 2 (Col6a2) Antikörper
  • collagen type VI alpha 2 chain (Col6a2) Antikörper
  • Col6a-2 Antikörper
  • PP3610 Antikörper

Bezeichner auf Proteinebene für COL6A2

collagen alpha-2(VI) chain , alpha 2 type VI collagen , collagen, type VI, alpha 2 , collagen VI, alpha-2 polypeptide , human mRNA for collagen VI alpha-2 C-terminal globular domain , collagen type VI alpha 2 , procollagen, type VI, alpha 2 , type VI collagen alpha-2 subunit

GENE ID SPEZIES
282194 Bos taurus
474056 Pan troglodytes
567771 Danio rerio
709493 Macaca mulatta
100224039 Taeniopygia guttata
8604757 Thermomonospora curvata DSM 43183
100055332 Equus caballus
100602701 Nomascus leucogenys
1292 Homo sapiens
100101552 Sus scrofa
12834 Mus musculus
361821 Rattus norvegicus
396292 Gallus gallus
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