anti-Collagen, Type IV, alpha 3 (Goodpasture Antigen) Binding Protein (COL4A3BP) Antikörper

COL4A3BP encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Zusätzlich bieten wir Ihnen COL4A3BP Proteine (10) und COL4A3BP Kits (9) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
COL4A3BP 365652  
COL4A3BP 68018 Q9EQG9
COL4A3BP 10087 Q9Y5P4
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-COL4A3BP Antikörper auf antikoerper-online.de

Showing 10 out of 105 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-COL4A3BP Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Hela cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, WB <span>COL4A3BP Antibody (N-term) western blot analysis in MDA-MB453 cell line lysates (35µg/lane).This demonstrates the COL4A3BP antibody detected the COL4A3BP protein (arrow).</span> 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Maus Ziege Unkonjugiert ELISA, WB ABIN238598 (0.5µg/ml) staining of mouse heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Ziege Unkonjugiert ELISA, WB ABIN308432 (1µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Ziege Unkonjugiert ELISA, WB Western Blot: COL4A3BP Antibody [ABIN42995696] - (0.5ug/ml) staining of mouse heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Ziege Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$455.40
Details
Human Ziege Unkonjugiert ELISA, WB Western Blot: COL4A3BP Antibody [NBP1-06028] (1ug/ml) staining of Human Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Kaninchen Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 11 bis 13 Tage
$468.05
Details
Fledermaus Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Human Kaninchen Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details

COL4A3BP Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Rat (Rattus) , ,
, ,

, , , , , , , , , , , , ,
Mouse (Murine) , ,
, ,

, , , , , , , , , , , , , , , ,
Human , ,
, , ,
,
, , , , , , , , , , , , , , , ,

Am meisten referenzierte anti-COL4A3BP Antikörper

  1. Human Polyclonal COL4A3BP Primary Antibody für ELISA, WB - ABIN451598 : Kudo, Kumagai, Tomishige, Yamaji, Wakatsuki, Nishijima, Hanada, Kato: Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

  2. Human Polyclonal COL4A3BP Primary Antibody für ELISA, WB - ABIN4299569 : Swanton, Marani, Pardo, Warne, Kelly, Sahai, Elustondo, Chang, Temple, Ahmed, Brenton, Downward, Nicke: Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs. in Cancer cell 2007 (PubMed)

Weitere Antikörper gegen COL4A3BP Interaktionspartner

Mouse (Murine) Collagen, Type IV, alpha 3 (Goodpasture Antigen) Binding Protein (COL4A3BP) Interaktionspartner

  1. CERT protein deficiency compromises mitochondrial function and leads to senescence in primary cells.

  2. knockdown of CERT alone was not sufficient to increase young oocyte's susceptibility to death

  3. GPBP directs myofibril formation through interaction with intracellular downstream effector 130-kDa GPBP-interacting protein (zeige FILIP1L Antikörper)

  4. VEGF (zeige VEGFA Antikörper) inhibitor also partially prevented the stimulation of alpha3(IV (zeige COL4a3 Antikörper)) collagen by transforming growth factor (TGF)-beta1 (zeige TGFB1 Antikörper).

  5. CERT is a physiological substrate of PP2Cepsilon and that dephosphorylation of CERT by PP2Cepsilon may play an important role in the regulation of ceramide trafficking from the ER to the Golgi apparatus.

  6. CERT can attenuate a key metabolic protective mechanism against ceramide-induced apoptosis in keratinocytes

  7. CERT is an essential gene for mouse development and embryonic survival and is critical for mitochondrial integrity.

Zebrafish Collagen, Type IV, alpha 3 (Goodpasture Antigen) Binding Protein (COL4A3BP) Interaktionspartner

  1. study found both GPBP isoforms are expressed during early development &, when depleted, lead to apoptosis; results suggest GPBP is an important factor for normal skeletal muscle & brain development

Human Collagen, Type IV, alpha 3 (Goodpasture Antigen) Binding Protein (COL4A3BP) Interaktionspartner

  1. Data suggest that isolated PH and START domains of CERT interact with each other; START domain binds to PH domain at same site for PtdIns[4]P-binding; mutations disrupting PH-START interaction increase both PtdIns[4]P-binding affinity and ceramide transfer activity. (PH domain = N-terminal pleckstrin (zeige PLEK Antikörper) homology domain; START domain = StAR-related lipid transfer domain; PtdIns[4]P = phosphatidylinositol 4-phosphate)

  2. Cells expressing mitoCERT import ceramides into mitochondria and undergo Bax (zeige BAX Antikörper)-dependent apoptosis.

  3. phosphorylation of CERT at the FFAT motif-adjacent serine affects its affinity for VAP (zeige F10 Antikörper), which may regulate the inter-organelle trafficking of ceramide in response to the perturbation of cellular sphingomyelin and/or other sphingolipids

  4. Both CERT isoforms, when immobilized, bind the globular head region of C1q and initiate the classical complement pathway. C1q binds endogenous CERTL on the surface of apoptotic cells.

  5. Structural basis for the Golgi association by the pleckstrin (zeige PLEK Antikörper) homology domain of the ceramide trafficking protein (CERT)

  6. CERT is at a convergence point of non-vesicular and vesicular transport processes and plays a central role within the PKD (zeige PRKD1 Antikörper) signaling network at the Golgi complex. (Review)

  7. Loss of the ceramide transfer protein augments EGF receptor (zeige EGFR Antikörper) signaling in breast cancer.

  8. The START domain in GPBP is important for this interaction. SAP (zeige APCS Antikörper) and GPBP form complexes in blood and partly colocalize in amyloid plaques from Alzheimer disease patients.

  9. This review is focused on ceramide transfer protein (CERT) as a major regulator of ceramide flux in the cell. [review]

  10. during cellular stress, disassembly of Golgi structure together with inactivation of CERT by caspases causes a reduction in ceramide trafficking and sphingomyelin synthesis, and could contribute to the cellular response to pro-apoptotic stress

COL4A3BP Antigen-Profil

Protein Überblick

This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Three transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit COL4A3BP

  • collagen type IV alpha 3 binding protein (COL4A3BP) Antikörper
  • collagen type IV alpha 3 binding protein (Col4a3bp) Antikörper
  • collagen, type IV, alpha 3 (Goodpasture antigen) binding protein (Col4a3bp) Antikörper
  • collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a (col4a3bpa) Antikörper
  • collagen, type IV, alpha 3 (Goodpasture antigen) binding protein L homeolog (col4a3bp.L) Antikörper
  • 2810404O15Rik Antikörper
  • 9230101K08Rik Antikörper
  • AU016711 Antikörper
  • cert Antikörper
  • certl Antikörper
  • cetp Antikörper
  • col4a3bp Antikörper
  • gpbp Antikörper
  • stard11 Antikörper
  • wu:fc37f11 Antikörper
  • zgc:92147 Antikörper

Bezeichner auf Proteinebene für COL4A3BP

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein , alpha 3 type IV collagen binding protein , collagen type IV alpha-3-binding protein , procollagen, type IV, alpha 3 (Goodpasture antigen) binding protein , collagen, type IV, alpha 3 binding protein , START domain-containing protein 11 , ceramide transfer protein , ceramide transport protein , goodpasture antigen-binding protein , stAR-related lipid transfer protein 11 , stARD11 , WITHDRAWN:zgc:92147 , cert , StAR-related lipid transfer (START) domain containing 11 , ceramide transporter , hCERT , lipid-transfer protein CERTL , GPBP

GENE ID SPEZIES
471515 Pan troglodytes
365652 Rattus norvegicus
427209 Gallus gallus
68018 Mus musculus
612799 Canis lupus familiaris
796455 Danio rerio
10087 Homo sapiens
432007 Xenopus laevis
286797 Bos taurus
100727340 Cavia porcellus
Ausgewählte Anbieter für anti-COL4A3BP (COL4A3BP) Antikörper
Haben Sie etwas anderes gesucht?