Cleavage and Polyadenylation Specific Factor 6, 68kDa (CPSF6) ELISA Kits

The protein encoded by CPSF6 is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. Zusätzlich bieten wir Ihnen CPSF6 Antikörper (55) und CPSF6 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Maus CPSF6 CPSF6 432508 Q6NVF9
Anti-Human CPSF6 CPSF6 11052 Q16630
Anti-Ratte CPSF6 CPSF6 299811  
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Weitere ELISA Kits für CPSF6 Interaktionspartner

Mouse (Murine) Cleavage and Polyadenylation Specific Factor 6, 68kDa (CPSF6) Interaktionspartner

  1. Here we report that the CFIm subunits NUDT21/CPSF5 (zeige NUDT21 ELISA Kits) and CPSF6 are highly enriched in mouse male germ cells relative to somatic cells.

Human Cleavage and Polyadenylation Specific Factor 6, 68kDa (CPSF6) Interaktionspartner

  1. Studies suggest that binding of cleavage factor Im (CFIm) may be one of the earliest steps in promoting formation of an active cleavage complex.

  2. CPSF6 binding to its docking site in HIV-1 capsid leads to the recruitment of CFIm tetramer, suggesting that CFIm mediates CPSF6 function(s) in integration site targeting.

  3. integration targeting proceeds via two distinct mechanisms: capsid-CPSF6 binding directs HIV-1 to actively transcribed euchromatin, where the integrase-LEDGF/p75 (zeige PSIP1 ELISA Kits) interaction drives integration into gene bodies.

  4. NUP153 (zeige NUP153 ELISA Kits) and CPSF6 have overlapping binding sites, but each makes unique capsid monomers (CA) interactions. Multiple ligands share an overlapping interface in HIV-1 capsid that is lost upon viral disassembly.

  5. Structural basis of HIV-1 capsid recognition by PF74 and CPSF6.

  6. study uncovers two opposing CA-dependent functions of CPSF6 in HIV-1 replication in vivo; however, the benefit for binding CPSF6 appears to outweigh the cost, providing support for a vital function of CPSF6 during HIV-1 replication in vivo

  7. CPSF6 binds specifically to a novel proteinprotein interface on the N-terminal domain of HIV-1 capsid protein (CA).

  8. These results suggested that inhibition of HIV-1 by TNPO3 (zeige TNPO3 ELISA Kits)-depleted cells requires CPSF6.

  9. Loss-of-function of CFIm68 and CFIm25 (zeige NUDT21 ELISA Kits) leads to a transcriptome-wide increase in the use of proximal polyadenylation sites in HEK293 cells.

  10. TNPO3 (zeige TNPO3 ELISA Kits) promotes HIV-1 infectivity indirectly, by shifting the CA-binding protein CPSF6 to the nucleus, thus preventing the excessive HIV-1 CA stability that would otherwise result from cytoplasmic accumulation of CPSF6.

CPSF6 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins.

Genbezeichner und Symbole assoziert mit CPSF6

  • cleavage and polyadenylation specific factor 6 (CPSF6) Antikörper
  • cleavage and polyadenylation specific factor 6 S homeolog (cpsf6.S) Antikörper
  • cleavage and polyadenylation specific factor 6 (cpsf6) Antikörper
  • cleavage and polyadenylation specific factor 6 (Cpsf6) Antikörper
  • 4733401N12Rik Antikörper
  • AI256641 Antikörper
  • CFIM Antikörper
  • CFIM68 Antikörper
  • CPSF6 Antikörper
  • HPBRII-4 Antikörper
  • HPBRII-7 Antikörper
  • wu:fa22f12 Antikörper
  • zgc:85819 Antikörper

Bezeichner auf Proteinebene für CPSF6

cleavage and polyadenylation specific factor 6, 68kDa , cleavage and polyadenylation specificity factor subunit 6 , cleavage and polyadenylation specific factor 6, 68 kD subunit , CPSF 68 kDa subunit , cleavage and polyadenylation specificity factor 68 kDa subunit , cleavage factor Im complex 68 kDa subunit , pre-mRNA cleavage factor I, 68kD subunit , pre-mRNA cleavage factor Im (68kD) , pre-mRNA cleavage factor Im 68 kDa subunit , protein HPBRII-4/7

GENE ID SPEZIES
452068 Pan troglodytes
446580 Xenopus laevis
548671 Xenopus (Silurana) tropicalis
100013834 Monodelphis domestica
100220791 Taeniopygia guttata
100589466 Nomascus leucogenys
327069 Danio rerio
432508 Mus musculus
417844 Gallus gallus
11052 Homo sapiens
474441 Canis lupus familiaris
100152191 Sus scrofa
768231 Bos taurus
299811 Rattus norvegicus
100174771 Pongo abelii
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