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anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) Antikörper

Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. Zusätzlich bieten wir Ihnen Cleavage and Polyadenylation Specific Factor 4, 30kDa Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CPSF4 100360200  
CPSF4 54188 Q8BQZ5
CPSF4 10898 O95639
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Top anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa Antikörper auf antikoerper-online.de

Showing 10 out of 60 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of CPSF4 Antibody (Center) in Jurkat cell line l... 0.4 mL Anmelden zum Anzeigen 8 bis 10 Tage
407,00 €
Details
Huhn Kaninchen Unkonjugiert WB WB Suggested Anti-CPSF4 Antibody Titration: 0.2-1 ug/mlPositive Contro... 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of CPSF4 Antibody (Center) (ABIN653570) in Jurka... 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
600,64 €
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Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human gastric carcinoma labeled w... Lane 1: rat brain lysates Lane 2: human colon carcinoma lysates probed... 100 μL Anmelden zum Anzeigen 5 bis 7 Tage
277,90 €
Details
Human Maus Unkonjugiert DB 50 μg Anmelden zum Anzeigen 10 bis 13 Tage
281,63 €
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Human Kaninchen Unkonjugiert IP, WB 0.1 mL Anmelden zum Anzeigen 6 bis 8 Tage
484,00 €
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Human Kaninchen Unkonjugiert IP, WB 0.1 mL Anmelden zum Anzeigen 6 bis 8 Tage
484,00 €
Details
Hund Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
459,65 €
Details

CPSF4 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Rat (Rattus) , ,

Mouse (Murine) , , ,

Human , , , ,
,

Am meisten referenzierte anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa Antikörper

  1. Human Polyclonal CPSF4 Primary Antibody für EIA, WB - ABIN951684 : Twu, Kuo, Marklund, Krug: The H5N1 influenza virus NS genes selected after 1998 enhance virus replication in mammalian cells. in Journal of virology 2007 (PubMed)
    Zeige alle 4 Referenzen für ABIN951684

Weitere Antikörper gegen Cleavage and Polyadenylation Specific Factor 4, 30kDa Interaktionspartner

Human Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) Interaktionspartner

  1. unexpectedly found that CPSF (zeige CPSF3 Antikörper) subunits CPSF30 and Wdr33 (zeige WDR33 Antikörper) directly contact AAUAAA

  2. CPSF4 upregulates human TERT (zeige TERT Antikörper) promoter activity, human TERT (zeige TERT Antikörper) expression and telomerase activity.

  3. Data show that 4 drug-like compounds from traditional Chinese Medicine (TCM) database were selected as potential inhibitors for the cleavage and polyadenylation specific factor CPSF30-binding site of influenza A virus of non-structural protein 1 (NS1A).

  4. CPSF4 plays a critical role in regulating lung cancer cell proliferation and survival and may be a potential prognostic biomarker and therapeutic target for lung adenocarcinoma.

  5. Data show that the NS1A protein of the pathogenic H5N1 influenza A/Hong Kong/483/97 (HK97) virus isolated from humans has an intrinsic defect in CPSF30 binding.

Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) Antigen-Profil

Protein Überblick

Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs. Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Genbezeichner und Symbole assoziert mit CPSF4

  • cleavage and polyadenylation specific factor 4, 30kDa (CPSF4) Antikörper
  • cleavage and polyadenylation specific factor 4, 30kDa (Cpsf4) Antikörper
  • cleavage and polyadenylation specific factor 4 (LOC733099) Antikörper
  • cleavage and polyadenylation specific factor 4 (LOC100360200) Antikörper
  • cleavage and polyadenylation specific factor 4, 30kDa (cpsf4) Antikörper
  • cleavage and polyadenylation specific factor 4, 30kDa (LOC100224162) Antikörper
  • cleavage and polyadenylation specific factor 4 (Cpsf4) Antikörper
  • 30kDa Antikörper
  • C79664 Antikörper
  • CPSF30 Antikörper
  • NAR Antikörper
  • NEB1 Antikörper

Bezeichner auf Proteinebene für CPSF4

no arches , GLEAN_10339 , cleavage and polyadenylation specific factor 4 , cleavage and polyadenylation specificity factor subunit 4 , cleavage and polyadenylation specific factor 4, 30kDa , CPSF 30 kDa subunit , cleavage and polyadenylation specific factor 4, 30kD subunit , cleavage and polyadenylation specificity factor 30 kDa subunit , clipper homolog , clipper/CPSF 30K , musculus clipper/cleavage and polyadenylation specificity factor 30 kDa subunit , NS1 effector domain-binding protein 1 , cleavage-polyadenylation specificity factor, 30kD , neb-1 , no arches homolog , no arches-like zinc finger protein , cleavage-polyadenylation specificity factor, 30 kD

GENE ID SPEZIES
463572 Pan troglodytes
660072 Tribolium castaneum
733099 Bombyx mori
100360200 Rattus norvegicus
444766 Xenopus laevis
493312 Xenopus (Silurana) tropicalis
708119 Macaca mulatta
100224162 Taeniopygia guttata
54188 Mus musculus
304277 Rattus norvegicus
10898 Homo sapiens
416494 Gallus gallus
489859 Canis lupus familiaris
280875 Bos taurus
Ausgewählte Anbieter für anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) Antikörper
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