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C19orf2 encodes member of the prefoldin family of molecular chaperones. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.
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This work uncovers that URI-regulated OGT (zeige OGT Antikörper) confers c-MYC (zeige MYC Antikörper)-dependent survival functions in response to glucose fluctuations.
Amplification of 19q12 CCNE1 (zeige CCNE1 Antikörper)/URI was found in 10.4% (28/270) and was significantly associated with type II endometrial cancer (EC) high grade, advanced FIGO stage, and aberrant tumor supressor p53 (zeige TP53 Antikörper) expression.
that KAP1 (zeige CDKN3 Antikörper) phosphorylation is decreased following recruitment of PP2A (zeige PPP2R4 Antikörper) by URI.
RMP (zeige ABCA4 Antikörper) status in tumors may be a useful marker in estimating prognosis in patients with hepatocellular carcinoma and in assisting in the selection of patients who are likely to benefit from adjuvant TACE (zeige ADAM17 Antikörper) to prevent relapse.
High URI1 expression is associated with epithelial ovarian cancer.
Results show that URI expression is essential for hepatocarcinogenesis and associated with poor survival.
URI may have an important role in the development of multiple myeloma and chemotherapeutic resistance through activation of the IL-6 (zeige IL6 Antikörper)/STAT3 (zeige STAT3 Antikörper) pathway.
Higher level of URI/RMP expression in high-grade endometrioid adenocarcinomas compared to tissues of adjacent endometrium or gland suggests a diagnostic and possibly, a prognostic value of URI/RMP in endometrioid adenocarcinoma.
Data show that while Art-27 (zeige UXT Antikörper) can bind AR directly, URI is bound to chromatin prior to hormone-dependent recruitment of AR, suggesting a role for URI in modulating AR recruitment to target genes.
Data show that URI is an "addicting" oncogene (zeige RAB1A Antikörper) selectively required for the survival of ovarian cancer cells with increased URI copy number.
Results show that RMP (zeige ABCA4 Antikörper) serves as a potent factor contributing to portal vein tumor thrombus by promoting IL-6 (zeige IL6 Antikörper) transcription.
This gene encodes member of the prefoldin family of molecular chaperones. The encoded protein functions as a scaffolding protein and plays roles in ubiquitination and transcription, in part though interactions with the RNA polymerase II subunit RPB5. This gene may play a role in multiple malignancies including ovarian cancer and hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 22.
chromosome 19 open reading frame 2
, RNA polymerase II subunit 5-mediating protein
, RPB5-mediating protein
, protein phosphatase 1 regulatory subunit 19
, protein phosphatase 1, regulatory subunit 19
, unconventional prefoldin RPB5 interactor 1
, unconventional prefoldin RPB5 interactor