anti-Chromodomain Helicase DNA Binding Protein 4 (CHD4) Antikörper

The product of CHD4 belongs to the SNF2/RAD54 helicase family. Zusätzlich bieten wir Ihnen CHD4 Proteine (8) und CHD4 Kits (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CHD4 1108 Q14839
CHD4 117535  
CHD4 107932 Q6PDQ2
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Top anti-CHD4 Antikörper auf antikoerper-online.de

Showing 10 out of 80 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-CHD4 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: OVCAR-3 cell lysate There is BioGPS gene expression data showing that CHD4 is expressed in OVCAR3 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using CHD4 Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of HepG2 cells, using CHD4 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert IP, PLA, WB Western Blot and Immunoprecipitation: CHD4/Mi2 beta Antibody [ABIN252858] - Detection of Human and Mouse CHD4/Mi2 beta by Western Blot (h&m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded), 293T (T, 50 mcg) and mouse NIH3T3 (M, 50 mcg) cells. Antibodies: Affinity purified rabbit anti-CHD4/Mi2 beta antibody ABIN252858 used for WB at 0.04 mcg/ml (A) and 0.1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. CHD4/Mi2 beta was also immunoprecipitated by rabbit anti-CHD4/Mi2 beta antibodies ABIN252857 and ABIN252859, which recognize other epitopes. . Detection: Chemiluminescence with exposure times of 10 seconds (A and B). Proximity Ligation Assay: CHD4 Antibody [ABIN2528580] - image shows representative results for PLA using three color fluorescence, including DAPI stained nuclei (blue), phalloidin stained cytoplasmic F-actin (green), and PLA positive signal (red). 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
Details
Human Kaninchen Unkonjugiert IP, WB Western Blot and Immunoprecipitation: CHD4/Mi2 beta Antibody [ABIN252859] - Detection of Human and Mouse CHD4/Mi2 beta by Western Blot (h&m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded), 293T (T, 50 mcg) and mouse NIH3T3 (M, 50 mcg) cells. Antibodies: Affinity purified rabbit anti-CHD4/Mi2 beta antibody ABIN252859 used for WB at 0.04 mcg/ml (A) and 0.1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. CHD4/Mi2 beta was also immunoprecipitated by rabbit anti-CHD4/Mi2 beta antibodies ABIN252858 and another anti-CHD4/Mi2 beta, which recognize other epitopes. Detection: Chemiluminescence with exposure times of 3 seconds (A and B). 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
Details
Human Kaninchen Unkonjugiert IP, WB Western Blot and Immunoprecipitation: CHD4/Mi2 beta Antibody [ABIN252857] - Detection of Human and Mouse CHD4/Mi2 beta by Western Blot (h&m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded), 293T (T, 50 mcg) and mouse NIH3T3 (M, 50 mcg) cells. Antibodies: Affinity purified rabbit anti-CHD4/Mi2 beta antibody ABIN252857 used for WB at 0.04 mcg/ml (A) and 0.1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. CHD4/Mi2 beta was also immunoprecipitated by rabbit anti-CHD4/Mi2 beta antibodies ABIN252858 and ABIN252859, which recognize downstream epitopes. Detection: Chemiluminescence with exposure times of 10 seconds (A and B). Western Blot: CHD4 Antibody  - Detection of Human CHD4/Mi2 beta by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-CHD4/Mi2 beta antibody  used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 100 μL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
Details
Fledermaus Kaninchen Unkonjugiert IHC (p), WB Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
801,43 €
Details
Human Maus Unkonjugiert WB Western Blot analysis of CHD4 expression in transfected 293T cell line by CHD4 monoclonal antibody (M01), clone 4H4. Lane 1: CHD4 transfected lysate(220 KDa). Lane 2: Non-transfected lysate. CHD4 monoclonal antibody (M01), clone 4H4 Western Blot analysis of CHD4 expression in HeLa NE. 100 μg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Details
Human Kaninchen Unkonjugiert IF, IHC, WB 100 μL Anmelden zum Anzeigen 12 Days
392,86 €
Details
Human Maus Unkonjugiert IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to CHD4 on formalin-fixed paraffin-embedded human transitional cell carcinoma. [antibody concentration 3 ug/ml] CHD4 monoclonal antibody (M01), clone 4H4 Western Blot analysis of CHD4 expression in Hela S3 NE . 100 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, WB Mi-2 beta antibody tested by immunofluorescence. Top left: HeLa cells stained with Mi-2 beta antibody (1:1,000). Top right: Same cells stained with alpha Tubulin mAb (Clone 5-B-1-2). Bottom left: Same cells stained with DAPI. Bottom right: Merge of all 3 images. Mi-2 beta antibody tested by Western blot. Whole-cell extract of mouse splenocytes stained with Mi-2 beta antibody (1:1,1000). 200 μL Anmelden zum Anzeigen 1 bis 3 Tage
497,22 €
Details

CHD4 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-CHD4 Antikörper

  1. Human Polyclonal CHD4 Primary Antibody für ICC, IF - ABIN2668534 : Curtis, Griffin: The chromatin-remodeling enzymes BRG1 and CHD4 antagonistically regulate vascular Wnt signaling. in Molecular and cellular biology 2012 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal CHD4 Primary Antibody für IP, PLA - ABIN252858 : Ma, Lin, Bartolomei, Schultz: Metastasis tumor antigen 2 (MTA2) is involved in proper imprinted expression of H19 and Peg3 during mouse preimplantation development. in Biology of reproduction 2010 (PubMed)

  3. Human Polyclonal CHD4 Primary Antibody für IP, WB - ABIN252859 : Gu, Hu, Ebrahem, Crabb, Mahfouz, Radivoyevitch, Crabb, Saunthararajah: Runx1 regulation of Pu.1 corepressor/coactivator exchange identifies specific molecular targets for leukemia differentiation therapy. in The Journal of biological chemistry 2014 (PubMed)

  4. Fruit Fly (Drosophila melanogaster) Monoclonal CHD4 Primary Antibody für IP, WB - ABIN2668526 : Murawska, Kunert, van Vugt, Längst, Kremmer, Logie, Brehm: dCHD3, a novel ATP-dependent chromatin remodeler associated with sites of active transcription. in Molecular and cellular biology 2008 (PubMed)

  5. Human Monoclonal CHD4 Primary Antibody für IHC (p), ELISA - ABIN560357 : Nishibuchi, Shibata, Hayakawa, Hayakawa, Ohtani, Sinmyozu, Tagami, Nakayama: Physical and functional interactions between the histone H3K4 demethylase KDM5A and the nucleosome remodeling and deacetylase (NuRD) complex. in The Journal of biological chemistry 2014 (PubMed)

  6. Human Polyclonal CHD4 Primary Antibody für IP, WB - ABIN252857 : Shakya, Kang, Chumley, Williams, Tantin: Oct1 is a switchable, bipotential stabilizer of repressed and inducible transcriptional states. in The Journal of biological chemistry 2011 (PubMed)

Weitere Antikörper gegen CHD4 Interaktionspartner

Human Chromodomain Helicase DNA Binding Protein 4 (CHD4) Interaktionspartner

  1. CHD3 (zeige CHD3 Antikörper) and CHD4 exhibit distinct nuclear localization patterns in unperturbed cells, revealing a subset of specific target genes.

  2. The findings identify that CHD4 deficiency preferentially impairs cell survival via increasing the level of p21 (zeige CDKN1A Antikörper).

  3. Mutation in CHD4 gene is associated with congenital heart defects.

  4. this work identifies CHD4 as an epigenetic coregulator of PAX3 (zeige PAX3 Antikörper)-FOXO1 (zeige FOXO1 Antikörper) activity, providing rational evidence for CHD4 as a potential therapeutic target in alveolar rhabdomyosarcoma.

  5. CHD4 recruits repressive chromatin proteins to sites of DNA damage repair, including DNA methyltransferases where it imposes de novo DNA methylation (zeige HELLS Antikörper). At TSGs, CHD4 retention helps maintain DNA hypermethylation-associated transcriptional silencing.

  6. this study identifies the Chd4-Tbx3 (zeige TBX3 Antikörper) axis in controlling ESC fate and a role of H2A.Z (zeige H2AFZ Antikörper) in maintaining the stability of Chd4 proteins.

  7. report provides evidence for the role of CHD4 in human development and expands an increasingly recognized group of Mendelian disorders involving chromatin remodeling and modification

  8. complex lacking CHD4 that has HDAC (zeige HDAC3 Antikörper) activity can exist as a stable species. The addition of recombinant CHD4 to this nucleosome deacetylase complex reconstitutes a NuRD complex with nucleosome remodeling activity.

  9. CHD4 plays a pivotal role in chemoresistance and the maintenance of stemness in liver cancer stem cells and is therefore a good target for the eradication of hepatocellular carcinoma.

  10. Acetyltransferase p300 (zeige EP300 Antikörper) collaborates with chromodomain helicase DNA-binding protein 4 (CHD4) to facilitate DNA double-strand break repair

Mouse (Murine) Chromodomain Helicase DNA Binding Protein 4 (CHD4) Interaktionspartner

  1. Chd4 mutant embryos died before birth and exhibited severe edema, blood-filled lymphatics, and liver hemorrhage. CHD4-deficient embryos developed normal lymphovenous (LV) valves, which regulate the return of lymph to the blood circulation; however, these valves lacked the fibrin-rich thrombi that prevent blood from entering the lymphatic system.

  2. This secreted effector, toxoplasma inhibitor of STAT1 (zeige STAT1 Antikörper)-dependent transcription (TgIST), translocates to the host cell nucleus, where it recruits mouse Mi-2/NuRD to STAT1 (zeige STAT1 Antikörper)-dependent promoters, resulting in altered chromatin and blocked transcription.

  3. this study shows that the chromatin remodeler Mi-2beta controls epidermal homeostasis by regulating the genes involved in keratinocyte and immune-cell activation to maintain an inactive state

  4. preservation of the identity of the two striated (zeige NSDHL Antikörper) muscle types depends on epigenetic repression of the alternate lineage gene program by the chromatin remodeling complex Chd4/NuRD.

  5. complex lacking CHD4 that has HDAC (zeige HDAC3 Antikörper) activity can exist as a stable species. The addition of recombinant CHD4 to this nucleosome deacetylase complex reconstitutes a NuRD complex with nucleosome remodeling activity.

  6. CHD4 depletion modulates expression of acute myeloid leukemia (zeige BCL11A Antikörper) cell genes that regulate tumor formation in vivo and colony formation in vitro.

  7. CHD4 allows cells to undertake lineage commitment in vivo by modulating the frequency with which lineage-specification genes are expressed.

  8. Chromatin immunoprecipitation assays showed that CHD4-containing NuRD complexes directly bound the promoters of these genes in endothelial cells

  9. Chd4, interacting with Hdac1 (zeige HDAC1 Antikörper)/2, cooperates with its related proteins Kap1 (zeige TRIM28 Antikörper) and Cbx1 (zeige CBX1 Antikörper) to bind at -207/-148 of the Sox9 (zeige SOX9 Antikörper) promoter.

  10. NuRD negatively regulates TIP5 (zeige BAZ2A Antikörper) expression, thereby inhibiting ribosomal DNA (rDNA) methylation and maintaining demethylation state of rDNA promoters.

Xenopus laevis Chromodomain Helicase DNA Binding Protein 4 (CHD4) Interaktionspartner

  1. CHD4 functions as a MAP required for MT stabilization and is involved in generating spindle bipolarity.

CHD4 Antigen-Profil

Protein Überblick

The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein.

Genbezeichner und Symbole assoziert mit CHD4

  • chromodomain helicase DNA binding protein 4 (CHD4) Antikörper
  • chromodomain helicase DNA binding protein 4a (chd4a) Antikörper
  • chromodomain helicase DNA binding protein 4b (chd4b) Antikörper
  • chromodomain helicase DNA binding protein 4 (chd4) Antikörper
  • chromodomain helicase DNA binding protein 4 (Chd4) Antikörper
  • 9530019N15Rik Antikörper
  • AA617397 Antikörper
  • b230399n07 Antikörper
  • BC005710 Antikörper
  • CHD4 Antikörper
  • D6Ertd380e Antikörper
  • im:7143343 Antikörper
  • MGC145363 Antikörper
  • Mi-2 Antikörper
  • Mi-2b Antikörper
  • Mi-2beta Antikörper
  • Mi2-BETA Antikörper
  • mKIAA4075 Antikörper
  • si:ch211-51m24.3 Antikörper
  • si:ch211-57k11.10 Antikörper
  • wu:fb44b12 Antikörper
  • wu:fd12d03 Antikörper

Bezeichner auf Proteinebene für CHD4

chromodomain helicase DNA binding protein 4 , chromodomain-helicase-DNA-binding protein 4 , ATP-dependent helicase CHD4 , CHD-4 , Mi-2 autoantigen 218 kDa protein , Mi-2 autoantigen , Mi-2 beta

GENE ID SPEZIES
418278 Gallus gallus
451788 Pan troglodytes
558344 Danio rerio
560622 Danio rerio
100059817 Equus caballus
100124711 Xenopus (Silurana) tropicalis
100515610 Sus scrofa
100539798 Meleagris gallopavo
100566510 Anolis carolinensis
1108 Homo sapiens
117535 Rattus norvegicus
107932 Mus musculus
380196 Xenopus laevis
477714 Canis lupus familiaris
506402 Bos taurus
Ausgewählte Anbieter für anti-CHD4 (CHD4) Antikörper
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