Chromodomain Helicase DNA Binding Protein 2 (CHD2) ELISA Kits

The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. Zusätzlich bieten wir Ihnen CHD2 Antikörper (35) und und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Human CHD2 CHD2 1106 O14647
Anti-Maus CHD2 CHD2 244059  
Anti-Ratte CHD2 CHD2 308738  
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Weitere ELISA Kits für CHD2 Interaktionspartner

Human Chromodomain Helicase DNA Binding Protein 2 (CHD2) Interaktionspartner

  1. study reports monozygotic twins with a global neurodevelopmental delay associated with an autism spectrum disorder, hypotonia, postnatal microcephaly, stereotypic movements and circadian rhythm alterations in association with late-onset epilepsy; identified a CHD2 mutation, previously described in association with a phenotypic spectrum overlapping our patients' phenotype

  2. Results indicate a PARP1 (zeige PARP1 ELISA Kits)-dependent mechanism that regulates non-homologous end-joining through localized chromatin expansion and deposition of the histone variant H3.3 by CHD2 at DNA breaks promoting DNA repair.

  3. CHD2 mutations are responsible in rare cases for generalized epilepsy with myoclonic-atonic seizures.

  4. CHD2 is a cancer driver and has a role as chromatin remodeler in chronic lymphocytic leukemia.

  5. CHD2 mutation is the first identified cause of the archetypal generalized photosensitive epilepsy syndrome

  6. CHD1 (zeige CHD1 ELISA Kits) and CHD2 act as positive regulators of HIV-1 gene expression.

  7. The phenotypic spectrum of CHD2 encephalopathy has distinctive features of myoclonic epilepsy with marked photosensitivity.

  8. Human CHD2 is a chromatin assembly ATPase (zeige DNAH8 ELISA Kits) regulated by its chromatin- and DNA-binding domains.

  9. Our findings suggest that CHD2 mutations are important in the etiological spectrum of Lennox-Gastaut syndrome.

  10. Genetic variants of BCL2 (zeige BCL2 ELISA Kits), GNAO1 (zeige GNAO1 ELISA Kits), and CHD2 are associated with non-obstructive azoospermia risk.

Mouse (Murine) Chromodomain Helicase DNA Binding Protein 2 (CHD2) Interaktionspartner

  1. Chd2 is essential in preventing suppressive chromatin formation for developmentally regulated genes and determines subsequent effects on developmental processes in the undifferentiated state.

  2. inactivation of CHD2 during neurogenesis might contribute to abnormal neurodevelopment

  3. The data indicated that MyoD determines cell fate and facilitates differentiation- dependent gene expression through Chd2-dependent deposition of H3.3 at myogenic loci prior to differentiation.

  4. Study present evidence that the Chd2 mutant cells are defective in their ability to repair DNA damage induced by ionizing and ultraviolet radiation.

  5. Our results demonstrate that mutation of Chd2 dramatically affects mammalian development and long-term survival.

  6. Chd2 heterozygous mutant mice exhibit increased extramedullary hematopoiesis and susceptibility to lymphomas.

  7. Chd2-mutant mice present with glomerulopathy, proteinuria, and significantly impaired kidney function.

CHD2 Antigen-Profil

Beschreibung des Gens

The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit CHD2

  • microRNA 3175 (MIR3175) Antikörper
  • chromodomain helicase DNA binding protein 2 (CHD2) Antikörper
  • chromodomain helicase DNA binding protein 2 (Chd2) Antikörper
  • 2810013C04Rik Antikörper
  • 2810040A01Rik Antikörper
  • 5630401D06Rik Antikörper
  • AI851092 Antikörper
  • BC029703 Antikörper
  • CHD2 Antikörper
  • DKFZp469E1718 Antikörper
  • EEOC Antikörper
  • MGC148727 Antikörper
  • MGC159952 Antikörper

Bezeichner auf Proteinebene für CHD2

chromodomain helicase DNA binding protein 2 , ATP-dependent helicase CHD2 , CHD-2 , chromodomain-helicase-DNA-binding protein 2

GENE ID SPEZIES
415507 Gallus gallus
453666 Pan troglodytes
535026 Bos taurus
100049803 Equus caballus
100174351 Pongo abelii
100550760 Meleagris gallopavo
1106 Homo sapiens
479028 Canis lupus familiaris
244059 Mus musculus
308738 Rattus norvegicus
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