anti-Chromobox Homolog 8 (CBX8) Antikörper

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. Zusätzlich bieten wir Ihnen CBX8 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CBX8 30951 Q9QXV1
CBX8 57332 Q9HC52
CBX8 303731  
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Top anti-CBX8 Antikörper auf antikoerper-online.de

Showing 10 out of 137 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-CBX8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-CBX8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: COLO205 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-CBX8 Antibody Titration: 2.5ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate WB Suggested Anti-CBX8  Antibody Titration: 2.5 µg/mL ELISA Titer: 1:1562500  Positive Control: Jurkat cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
288,68 €
Details
Human Kaninchen Unkonjugiert EIA, WB CBX8 Antibody (Center) western blot analysis in mouse liver tissue lysates (35µg/lane).This demonstrates the CBX8 antibody detected the CBX8 protein (arrow). 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB The anti-CBX8 C-term Pab (ABIN389089) is used in Western blot to detect CBX8 in mouse kidney tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Ziege Unkonjugiert ELISA, WB ABIN334369 (0.1µg/ml) staining of K562 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
Details
Human Kaninchen Unkonjugiert IP, WB 100 μL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
Details
Human Maus Unkonjugiert FACS, ELISA, WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
494,23 €
Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
Details

CBX8 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine)
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Am meisten referenzierte anti-CBX8 Antikörper

  1. Human Polyclonal CBX8 Primary Antibody für EIA, WB - ABIN951075 : Obuse, Yang, Nozaki, Goto, Okazaki, Yoda et al.: Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the ... in Genes to cells : devoted to molecular & cellular mechanisms 2004 (PubMed)
    Zeige alle 5 Referenzen für 951075

  2. Human Polyclonal CBX8 Primary Antibody für EIA, IHC (p) - ABIN357753 : Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003 (PubMed)
    Zeige alle 3 Referenzen für 357753

  3. Human Polyclonal CBX8 Primary Antibody für IHC (p), WB - ABIN389089 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Zeige alle 3 Referenzen für 389089

  4. Human Polyclonal CBX8 Primary Antibody für IP, WB - ABIN258057 : Maertens, El Messaoudi-Aubert, Elderkin, Hiom, Peters: Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor. in The EMBO journal 2010 (PubMed)
    Zeige alle 2 Referenzen für 258057

  5. Human Monoclonal CBX8 Primary Antibody für FACS, ELISA - ABIN1724766 : Dietrich, Bracken, Trinh, Schjerling, Koseki, Rappsilber, Helin, Hansen: Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus. in The EMBO journal 2007 (PubMed)

  6. Cow (Bovine) Polyclonal CBX8 Primary Antibody für WB - ABIN2775902 : Bárdos, Saurin, Tissot, Duprez, Freemont: HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties. in The Journal of biological chemistry 2000 (PubMed)

Weitere Antikörper gegen CBX8 Interaktionspartner

Mouse (Murine) Chromobox Homolog 8 (CBX8) Interaktionspartner

  1. CBX8 plates roles in epigenetic regulation in DNA damage response.

  2. Cbx8 is upregulated and recruited to activated genes during embryonic stem cell differentiation.

  3. CBX8 plays an essential role in MLL (zeige MLL Antikörper)-AF9 (zeige MLLT3 Antikörper) transcriptional regulation and leukemogenesis.

  4. Pcl2 (zeige MTF2 Antikörper)-PRC2 facilitates both PRC2 recruitment to the inactive X chromosome in differentiating XX ES cells and PRC2 recruitment to target genes in undifferentiated ES cells.

  5. Huntingtin (zeige HTT Antikörper) is a novel stimulator of polycomb (zeige CBX2 Antikörper) repressive complex 2.

Human Chromobox Homolog 8 (CBX8) Interaktionspartner

  1. CBX8 plates roles in epigenetic regulation in DNA damage response.

  2. IGF1 (zeige IGF1 Antikörper) can promote the colon cancer cell line, HCT116 cell, proliferation via promoting Cbx8 expression

  3. The difference in the SUZ12 (zeige SUZ12 Antikörper) and CBX8 genes expression were significantly divergent between tumors and their marginal tissues.

  4. These data suggest that CBX8 modulates SIPS through the RB-E2F1 pathway in CML cells and provide important insight into its application in CML treatment.

  5. Low CBX8 expression was associated with distant metastasis in colorectal cancer.

  6. CBX8 might emerge as an oncogene (zeige RAB1A Antikörper) for promoting the proliferation of tumor cells and raising the resistance of neoplasms to chemotherapy.

  7. The presence of CBX8-GFP in the same focus had a minor impact on BMI1 and RING1 recovery kinetics.

  8. Interaction with CBX8 precludes AF9 (zeige MLLT3 Antikörper)-DOT1L (zeige DOT1L Antikörper) binding.

  9. CBX8 cooperated with SIRT1 (zeige SIRT1 Antikörper) for suppressing p53 (zeige TP53 Antikörper) acetylation induced by Sirtinol and etoposide/TSA (zeige PRDX2 Antikörper). Upon ectopic expression, CBX8 or SIRT1 (zeige SIRT1 Antikörper) repressed the expression of p21(WAF1 (zeige CDKN1A Antikörper)) by inhibiting p53 (zeige TP53 Antikörper) binding to the promoter.

  10. CBX8 plays an essential role in MLL (zeige MLL Antikörper)-AF9 (zeige MLLT3 Antikörper) transcriptional regulation and leukemogenesis.

CBX8 Antigen-Profil

Protein Überblick

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones\; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Genbezeichner und Symbole assoziert mit CBX8

  • chromobox homolog 8 (cbx8) Antikörper
  • chromobox homolog 8 (CBX8) Antikörper
  • chromobox 8 (Cbx8) Antikörper
  • chromobox homolog 8 (Cbx8) Antikörper
  • chromobox homolog 8a (Pc class homolog, Drosophila) (cbx8a) Antikörper
  • cbx8 Antikörper
  • MGC147589 Antikörper
  • PC3 Antikörper
  • RC1 Antikörper

Bezeichner auf Proteinebene für CBX8

chromobox homolog 8 , chromobox protein homolog 8 , mPc3 , polycomb 3 homolog , Pc class 3 homolog , chromobox homolog 8 (Pc class homolog, Drosophila) , polycomb 3 , rectachrome 1 , chromobox-like protein 8 , chromobox homolog 8 (Pc class homolog) , chromobox homolog 8a

GENE ID SPEZIES
779897 Xenopus (Silurana) tropicalis
100604409 Nomascus leucogenys
30951 Mus musculus
57332 Homo sapiens
608591 Canis lupus familiaris
506458 Bos taurus
303731 Rattus norvegicus
496172 Xenopus laevis
100514536 Sus scrofa
422084 Gallus gallus
100150672 Danio rerio
Ausgewählte Anbieter für anti-CBX8 (CBX8) Antikörper
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