anti-Chromobox Homolog 8 (CBX8) Antikörper

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. Zusätzlich bieten wir Ihnen CBX8 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CBX8 30951 Q9QXV1
CBX8 57332 Q9HC52
CBX8 303731  
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Top anti-CBX8 Antikörper auf antikoerper-online.de

Showing 10 out of 154 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-CBX8 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:12500<br><b>Positive Control: </b>COLO205 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-CBX8 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-CBX8 Antibody Titration: </b>2.5ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Jurkat cell lysate WB Suggested Anti-CBX8 <br /> Antibody Titration: 2.5 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert EIA, WB <span>CBX8 Antibody (Center) western blot analysis in mouse liver tissue lysates (35µg/lane).This demonstrates the CBX8 antibody detected the CBX8 protein (arrow).</span> 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB The anti-CBX8 C-term Pab (ABIN389089) is used in Western blot to detect CBX8 in mouse kidney tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Ziege Unkonjugiert ELISA, WB ABIN334369 (0.1µg/ml) staining of K562 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$326.89
Details
Human Maus Unkonjugiert FACS, ELISA, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$430.10
Details
Human Kaninchen Unkonjugiert IP, WB Western Blot: Cbx8 Antibody  - Detection of Human CBX8 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa and 293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-CBX8 antibody  used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$486.94
Details
Maus Kaninchen Unkonjugiert WB CBX8 Antibody (Center) (ABIN658577) western blot analysis in mouse liver tissue lysates (35 µg/lane). This demonstrates the CBX8 antibody detected the CBX8 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details

CBX8 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine)
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Am meisten referenzierte anti-CBX8 Antikörper

  1. Human Polyclonal CBX8 Primary Antibody für IP, WB - ABIN258057 : Maertens, El Messaoudi-Aubert, Elderkin, Hiom, Peters: Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor. in The EMBO journal 2010 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal CBX8 Primary Antibody für FACS, ELISA - ABIN1724765 : Dietrich, Bracken, Trinh, Schjerling, Koseki, Rappsilber, Helin, Hansen: Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus. in The EMBO journal 2007 (PubMed)

Weitere Antikörper gegen CBX8 Interaktionspartner

Mouse (Murine) Chromobox Homolog 8 (CBX8) Interaktionspartner

  1. Cbx8 associates with non-PRC1 (zeige PRC1 Antikörper) complexes containing the H3K4 methyltransferase complex component WDR5 (zeige WDR5 Antikörper), which together regulate Notch (zeige NOTCH1 Antikörper) gene expression.

  2. CBX8 plates roles in epigenetic regulation in DNA damage response.

  3. Cbx8 is upregulated and recruited to activated genes during embryonic stem cell differentiation.

  4. CBX8 plays an essential role in MLL (zeige MLL Antikörper)-AF9 (zeige MLLT3 Antikörper) transcriptional regulation and leukemogenesis.

  5. Pcl2 (zeige MTF2 Antikörper)-PRC2 facilitates both PRC2 recruitment to the inactive X chromosome in differentiating XX ES cells and PRC2 recruitment to target genes in undifferentiated ES cells.

  6. Huntingtin (zeige HTT Antikörper) is a novel stimulator of polycomb (zeige CBX2 Antikörper) repressive complex 2.

Human Chromobox Homolog 8 (CBX8) Interaktionspartner

  1. The data suggest that high expression of CBX8 plays a critical oncogenic role in aggressiveness of urothelial carcinoma cells of the bladder through promoting cancer cell proliferation by repressing the p53 (zeige TP53 Antikörper) pathway, and CBX8 could be used as a novel predictor for muscle invasive bladder cancer patients.

  2. CBX8 binds to H3K27me3 at bivalent promoters during germinal center formation, and recruits a novel PRC1 (zeige PRC1 Antikörper)-BCOR (zeige BCOR Antikörper) complex at BCL6 (zeige BCL6 Antikörper) binding sites to specifically silence genes in the germinal center and promote lymphomagenesis

  3. CBX8 plates roles in epigenetic regulation in DNA damage response.

  4. IGF1 (zeige IGF1 Antikörper) can promote the colon cancer cell line, HCT116 cell, proliferation via promoting Cbx8 expression

  5. The difference in the SUZ12 and CBX8 genes expression were significantly divergent between tumors and their marginal tissues.

  6. These data suggest that CBX8 modulates SIPS through the RB-E2F1 pathway in CML cells and provide important insight into its application in CML treatment.

  7. Low CBX8 expression was associated with distant metastasis in colorectal cancer.

  8. CBX8 might emerge as an oncogene (zeige RAB1A Antikörper) for promoting the proliferation of tumor cells and raising the resistance of neoplasms to chemotherapy.

  9. The presence of CBX8-GFP in the same focus had a minor impact on BMI1 and RING1 recovery kinetics.

  10. Interaction with CBX8 precludes AF9 (zeige MLLT3 Antikörper)-DOT1L (zeige DOT1L Antikörper) binding.

CBX8 Antigen-Profil

Protein Überblick

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones\; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Genbezeichner und Symbole assoziert mit CBX8

  • chromobox 8 (cbx8) Antikörper
  • chromobox 8 (CBX8) Antikörper
  • chromobox 8 (Cbx8) Antikörper
  • chromobox 8 S homeolog (cbx8.S) Antikörper
  • chromobox homolog 8a (Pc class homolog, Drosophila) (cbx8a) Antikörper
  • cbx8 Antikörper
  • MGC147589 Antikörper
  • PC3 Antikörper
  • RC1 Antikörper

Bezeichner auf Proteinebene für CBX8

chromobox homolog 8 , chromobox protein homolog 8 , mPc3 , polycomb 3 homolog , Pc class 3 homolog , chromobox homolog 8 (Pc class homolog, Drosophila) , polycomb 3 , rectachrome 1 , chromobox-like protein 8 , chromobox homolog 8 (Pc class homolog) , chromobox homolog 8a

GENE ID SPEZIES
779897 Xenopus (Silurana) tropicalis
100604409 Nomascus leucogenys
30951 Mus musculus
57332 Homo sapiens
608591 Canis lupus familiaris
506458 Bos taurus
303731 Rattus norvegicus
496172 Xenopus laevis
100514536 Sus scrofa
422084 Gallus gallus
100150672 Danio rerio
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