Chromobox Homolog 5 Proteine (CBX5)

CBX5 encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. Zusätzlich bieten wir Ihnen CBX5 Antikörper (272) und CBX5 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CBX5 23468 P45973
Ratte CBX5 CBX5 300266  
CBX5 12419 Q61686
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Top CBX5 Proteine auf

Showing 7 out of 8 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 11 bis 15 Tage
303,81 €
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
HOST_Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
218,90 €
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
HOST_Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 6 bis 8 Tage
374,15 €

CBX5 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Chromobox Homolog 5 (CBX5) Interaktionspartnern

Human Chromobox Homolog 5 (CBX5) Interaktionspartner

  1. Identify a nucleosome interaction module within KDM2A (zeige KDM2A Proteine) consisting of a CXXC type zinc finger, a PHD (zeige PDC Proteine) domain and a newly identified Heterochromatin Protein 1 (HP1 (zeige DEFA1 Proteine)) interaction motif that mediates direct binding between KDM2A (zeige KDM2A Proteine) and HP1 (zeige DEFA1 Proteine). This nucleosome interaction module enables KDM2A (zeige KDM2A Proteine) to decode nucleosomal H3K9me3 modification in addition to CpG methylation signals.

  2. These data suggests that up-regulated HP1A (zeige TFF1 Proteine) and H3K9me3 in glioma cells are functionally associated with glioma pathogenesis and progression.

  3. Loss of HP1alpha and gamma isoforms inhibits the upregulation of Suv39h1 (zeige SUV39H1 Proteine) and H3K9me3 that is observed under stress conditions.

  4. we showed the essential role of HP1 (zeige DEFA1 Proteine) in regulating HR through BRCA1/BARD1 (zeige BARD1 Proteine)-mediated accumulation of FANCJ and CtIP (zeige RBBP8 Proteine) at DSB sites. This mechanism may affect tumorigenesis and chemosensitivity and is thus of high clinical significance.

  5. We demonstrate that an hnRNPA1 (zeige HNRNPA1 Proteine) and CBX5 bi-directional core promoter fragment does not comprise intrinsic capacity for specific CBX5 down-regulation in metastatic cells

  6. HP1alpha plays an important role in the differentiation and angiogenic function of Endothelial Progenitor Cells.

  7. Jra recruits the HP1a (zeige TFF1 Proteine)/KDM4A (zeige KDM4A Proteine) complex to its gene body region upon osmotic stress to reduce H3K36 methylation levels and disrupt H3K36 methylation-dependent histone deacetylation

  8. SET interacts with the Kruppel-associated box (KRAB)-associated co-repressor KAP1 (zeige CDKN3 Proteine), and its overexpression results in the sustained retention of KAP1 (zeige CDKN3 Proteine) and Heterochromatin protein 1 (HP1 (zeige DEFA1 Proteine)) on chromatin

  9. HP1 (zeige DEFA1 Proteine) regulates this gene's alternative splicing in a methylation-dependent manner by recruiting splicing factors to its methylated form.

  10. PIP5K1A (zeige PIP5K1A Proteine) modulates ribosomal RNA gene silencing through its interaction with histone H3 (zeige HIST3H3 Proteine) lysine 9 trimethylation and heterochromatin protein HP1-alpha.

Mouse (Murine) Chromobox Homolog 5 (CBX5) Interaktionspartner

  1. HP1-alpha oligomerization is critical to the maintenance of heterochromatin and the tunable dynamics of this HP1 isoform.

  2. demonstrate an actin-driven differential modulation of core histone H2B and heterochromatin HP1alpha protein dynamics with chromatin

  3. the molecular behavior of HP1alpha throughout the cell cycle

  4. There is a functional link between prelamin A, HP1alpha, chromatin remodeling, DNA repair, and early senescence in Zmpste24 (zeige Zmpste24 Proteine)-deficient mice, suggesting a potential therapeutic strategy for laminopathy-based premature aging via the intervention of HP1alpha.

  5. the TIF1beta (zeige TRIM28 Proteine)-HP1 system functions as a critical repressive machinery that targets genes not normally activated in the hematopoietic compartment, thereby maintaining the transcriptional signature specific to HSCs.

  6. HP1 mobility in apoptotic cells appeared to be unique.

  7. Elimination of HP1alpha by siRNA interfered with centromere relocation from heterochromatin surrounding NPBs to pro-chromocenters at the two-cell stage but did not affect preimplantation develoment to the blastocyst stage.

  8. Depletion of Senp7 (zeige SENP7 Proteine) delocalizes HP1 alpha from pericentric heterochromatin without affecting H3K9me3 levels.

  9. The interplay between MU2 (zeige AP2M1 Proteine) and HP1a is dynamic and may be different in euchromatin and heterochromatin during DNA break recognition and repair.

  10. KAP1 (zeige TRIM28 Proteine) and HP1 tether activation-induced cytidine deaminase (zeige AICDA Proteine) (AID) to H3K9me3 residues at the donor switch region, thus linking AID to epigenetic modifications during class switch recombination.

CBX5 Protein Überblick

Protein Überblick

Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.

Genbezeichner und Symbole assoziert mit Chromobox Homolog 5 Proteine (CBX5)

  • chromobox homolog 5 (CBX5)
  • chromobox homolog 5 (HP1 alpha homolog, Drosophila) (cbx5)
  • chromobox homolog 5 (HP1 alpha homolog, Drosophila) (CBX5)
  • chromobox homolog 5 (Cbx5)
  • chromobox homolog 5 (cbx5)
  • defensin, alpha 1B (DEFA1B)
  • chromobox 5 (Cbx5)
  • 2610029O15Rik Protein
  • C75991 Protein
  • cbx5 Protein
  • HNP-1 Protein
  • HP-1 Protein
  • HP1 Protein
  • Hp1a Protein
  • Hp1alpha Protein
  • id:ibd2026 Protein
  • MGC64354 Protein
  • wu:fc63e02 Protein
  • wu:fe47g12 Protein
  • wu:fi03h05 Protein
  • zgc:158601 Protein

Bezeichner auf Proteinebene für Chromobox Homolog 5 Proteine (CBX5)

HP1 alpha homolog , HP1-ALPHA , HP1Hs alpha , antigen p25 , chromobox homolog 5 (HP1 alpha homolog, Drosophila) , chromobox protein homolog 5 , heterochromatin protein 1 homolog alpha , heterochromatin protein 1-alpha , fc63e02 , chromobox-like protein 5 , chromobox-like protein 5 (HP1 alpha homolog, Drosophila) , neutrophil defensin 1 , HP1 alpha , chromobox homolog 5 , heterochromatin protein 1 alpha , mHP1(alpha) , chromobox homolog 5 tv3

23468 Homo sapiens
563396 Danio rerio
538885 Bos taurus
477593 Canis lupus familiaris
467011 Pan troglodytes
300266 Rattus norvegicus
100307036 Ovis aries
380557 Xenopus laevis
394502 Xenopus (Silurana) tropicalis
728358 Homo sapiens
12419 Mus musculus
100519426 Sus scrofa
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