Chromobox Homolog 2 (CBX2) ELISA Kits

CBX2 encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Zusätzlich bieten wir Ihnen CBX2 Antikörper (73) und CBX2 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Maus CBX2 CBX2 12416 P30658
Anti-Human CBX2 CBX2 84733 Q14781
Anti-Ratte CBX2 CBX2 303730  
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Weitere ELISA Kits für CBX2 Interaktionspartner

Mouse (Murine) Chromobox Homolog 2 (CBX2) Interaktionspartner

  1. the compaction region of CBX2 plays a key role in establishing proper axial patterning, thereby expanding the functional regions of this protein.

  2. We find that the N-terminus of Cbx2 is needed for its recruitment to mitotic chromosomes, whereas the C-terminus is required for its immobilization.

  3. Cbx2 targets PRC1 (zeige PRC1 ELISA Kits) to constitutive heterochromatin in mouse zygotes in a parent-of-origin-dependent manner.

  4. This study implicates Cbx2 in testis differentiation through regulating Sry (zeige SRY ELISA Kits) gene expression.

  5. Data show that Polycomb repressive complex 2 is necessary to maintain normal levels of OGT and for the correct cellular distribution of O-GlcNAc.

  6. Zfp277 in the transcriptional regulation of the Ink4a/Arf locus and the recruitment of PRC1 to the Ink4a/Arf locus

  7. these results suggest that the binding specificity of Cbx2 protein for methylated histones is regulated by phosphorylation.

  8. murine geminin (zeige GMNN ELISA Kits) associates transiently with members of the Hox (zeige MSH2 ELISA Kits)-repressing polycomb complex, with the chromatin of Hox (zeige MSH2 ELISA Kits) regulatory DNA elements and with Hox (zeige MSH2 ELISA Kits) proteins

  9. Polycomb protein M33 controls critical expansion of B- and T-lymphocyte precursors

  10. The Polycomb M33 gene is an essential upstream regulator of Ad4BP/SF1 (zeige NR5A1 ELISA Kits).

Human Chromobox Homolog 2 (CBX2) Interaktionspartner

  1. Data show that basal-like subgroup was enriched for aggressive tumors and somatic mutations in trithorax-group genes and it overexpressed polycomb genes EZH2 (zeige EZH2 ELISA Kits) and CBX2.

  2. CBX2 role in the sex development cascade is to stimulate the male pathway and concurrently inhibit the female pathway.

  3. CBX2 upregulation and amplification significantly correlated with metastatic progression and lower overall survival in many cancer types, particularly those of the breast

  4. This study does not support CBX2 gene disruption as a common cause of gonadal gonadal disorders of sex development.

  5. Two distinct mechanisms are involved in CBX2-mediated gene silencing. The short CBX2-2 isoform would repress the transcription in a PRC1 (zeige PRC1 ELISA Kits)-independent fashion, whereas gene repression by the long CBX2-1 isoform is mediated by the PRC1 (zeige PRC1 ELISA Kits) protein complex.

  6. CDYL (zeige CDYL ELISA Kits) functions as a molecular bridge between PRC2 and the repressive chromatin mark H3K27me3, forming a positive feedback loop to facilitate the establishment and propagation of H3K27me3 modifications along the chromatin

  7. hPc2 (zeige ELAC2 ELISA Kits) serves as a SUMO E3 ligase (zeige PIAS1 ELISA Kits) for cystathionine beta-synthase (zeige CBS ELISA Kits), increasing the efficiency of sumoylation.

CBX2 Antigen-Profil

Beschreibung des Gens

This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Genbezeichner und Symbole assoziert mit Chromobox Homolog 2 (CBX2) ELISA Kits

  • chromobox homolog 2 (cbx2) Antikörper
  • chromobox homolog 2 (CBX2) Antikörper
  • chromobox homolog 2 (Drosophila Pc class) (cbx2) Antikörper
  • chromobox 2 (Cbx2) Antikörper
  • chromobox homolog 2 (Cbx2) Antikörper
  • cbx2 Antikörper
  • cdca6 Antikörper
  • m33 Antikörper
  • MOD2 Antikörper
  • pc Antikörper
  • pc1 Antikörper
  • SRXY5 Antikörper
  • wu:fd20e09 Antikörper
  • zgc:103563 Antikörper

Bezeichner auf Proteinebene für Chromobox Homolog 2 (CBX2) ELISA Kits

chromobox homolog 2 , modifier 3 protein , chromobox protein homolog 2-like , chromobox homolog 2 (Pc class homolog, Drosophila) , chromobox protein homolog 2 , M33 polycomb-like protein , hromobox homolog 2 , polycomb , Pc class homolog , cell division cycle associated 6 , modifier 3 , Polycomb homolog Pc1 , chromobox homolog 2 (Pc class homolog)

GENE ID SPEZIES
100125497 Oryzias latipes
100410455 Callithrix jacchus
327291 Danio rerio
12416 Mus musculus
84733 Homo sapiens
398110 Xenopus laevis
426248 Gallus gallus
483349 Canis lupus familiaris
303730 Rattus norvegicus
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