Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A) ELISA Kits

Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50, p60 (CHAF1B\; MIM 601245), and p150 (CHAF1A) subunits that assembles histone octamers onto replicating DNA in vitro (Kaufman et al., 1995 [PubMed 7600578]).[supplied by OMIM, Mar 2008].. Zusätzlich bieten wir Ihnen CHAF1A Antikörper (55) und CHAF1A Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Ratte CHAF1A CHAF1A 363333  
Anti-Human CHAF1A CHAF1A 10036 Q13111
Anti-Maus CHAF1A CHAF1A 27221 Q9QWF0
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Weitere ELISA Kits für CHAF1A Interaktionspartner

Human Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A) Interaktionspartner

  1. Data show that the high expression of chromatin assembly factor 1 (zeige RBBP4 ELISA Kits), subunit A (p150) (CHAF1A) promotes cell proliferation and inhibits cell apoptosis, suggesting that CHAF1A may be developed as a prognosis biomarker and potential therapeutic target of epithelial ovarian cancer (EOC).

  2. CHAF1A inhibits NEIL1 (zeige NEIL1 ELISA Kits) initiated repair in vitro Subsequent restoration of the chaperone-BER complex in cell, presumably after completion of repair, suggests that histone chaperones sequester the repair complex for oxidized bases in non-replicating chromatin, and allow repair when oxidized bases are induced in the genome.

  3. Loss of CAF1 is associated with increased motility and invasive phenotypes seen in transformed cells.

  4. These data suggest that CAF-1 (zeige CHAF1B ELISA Kits)- and ASF1A (zeige ASF1A ELISA Kits)-H3-H4-dependent deposition of the histone (H3 (zeige HIST3H3 ELISA Kits)-H4)2 tetramers is compatible with MMR (zeige MRC1 ELISA Kits) and protects the discontinuous daughter strand from unnecessary degradation by MMR (zeige MRC1 ELISA Kits) machinery.

  5. Taken together, these results show that CHAF1A contributes to the proliferation of glioblastoma cells and may be developed as a de novo drug target and prognosis biomarker of glioblastoma.

  6. Novel functions for a separable domain of the p150 (zeige ABL1 ELISA Kits) protein, regulating protein and DNA interactions at the nucleolus.

  7. The frequency of positive CHAF1A staining in primary tumor mucosa (45.8% of 203 samples) was significantly elevated compared to normal mucosa (18.7% of samples). Increased expression was associated with cancer stage, tumor invasion and histological grade.

  8. Histone chaperone CHAF1A inhibits differentiation and promotes aggressive neuroblastoma (zeige ARHGEF16 ELISA Kits).

  9. CAF1 was hijacked by IE2 to facilitate the replication of the HCMV genome, suggesting chromatin assembly plays an important role in herpesviral DNA synthesis, but also provide a model of the virus-induced chromatin instability through CAF1.

  10. CAF (zeige KAT2B ELISA Kits)-I-dependent control of degradation of the discontinuous strands during mismatch repair.

Mouse (Murine) Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A) Interaktionspartner

  1. CAF-1 (zeige CNOT7 ELISA Kits) is an essential guardian of the genome in preimplantation mouse embryos.

  2. the histone chaperone CAF-1 (zeige CNOT7 ELISA Kits) to be a novel regulator of somatic cell identity during transcription-factor-induced cell-fate transitions and provide a potential strategy to modulate cellular plasticity in a regenerative setting

  3. Findings suggest that p150 may link the DNA-bound Gfi1 repressor complex to histones enabling modifications required for transcriptional silencing.

  4. This recruitment is strictly dependent on p150CAF-1, the largest subunit of chromatin assembly factor 1 (CAF-1 (zeige RBBP4 ELISA Kits)), and its ability to interact with HP1alpha (zeige CBX5 ELISA Kits).

  5. during DNA replication, the interaction of HP1 (zeige CBX5 ELISA Kits) with p150CAF-1 is essential to promote delivery of HP1 (zeige CBX5 ELISA Kits) molecules to heterochromatic sites

  6. findings suggest that CAF-1 (zeige CNOT7 ELISA Kits) is required for the maturation of heterochromatin during preimplantation development (zeige MTA2 ELISA Kits) and that CAF-1 (zeige CNOT7 ELISA Kits) is specifically required for heterochromatin organization in pluripotent embryonic cells

  7. Data show that human CAF-1 (p150) contains two PCNA (zeige PCNA ELISA Kits) interaction peptides, and suggest that these peptides are part of the mechanism that enables CAF-1 (zeige CNOT7 ELISA Kits) to function behind replication forks without interfering with other PCNA (zeige PCNA ELISA Kits)-mediated processes.

CHAF1A Antigen-Profil

Beschreibung des Gens

Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50, p60 (CHAF1B\; MIM 601245), and p150 (CHAF1A) subunits that assembles histone octamers onto replicating DNA in vitro (Kaufman et al., 1995

Genbezeichner und Symbole assoziert mit CHAF1A

  • chromatin assembly factor 1, subunit A (p150) (Chaf1a) Antikörper
  • chromatin assembly factor 1, subunit A (p150) (CHAF1A) Antikörper
  • chromatin assembly factor 1, subunit A (p150) (LOC100231993) Antikörper
  • chromatin assembly factor 1, subunit A (p150) (chaf1a) Antikörper
  • AL023013 Antikörper
  • AL024058 Antikörper
  • Cac1p Antikörper
  • CAF-1 Antikörper
  • CAF-1P150 Antikörper
  • CAF-I-p150 Antikörper
  • CAF-Ip150 Antikörper
  • CAF1 Antikörper
  • CAF1B Antikörper
  • CAF1P150 Antikörper
  • caip150 Antikörper
  • CHAF1A Antikörper
  • chaf1a-b Antikörper
  • P150 Antikörper
  • wu:fd14g10 Antikörper
  • xp150 Antikörper
  • zgc:153930 Antikörper

Bezeichner auf Proteinebene für CHAF1A

chromatin assembly factor 1, subunit A (p150) , chromatin assembly factor 1 subunit A-like , CAF-1 subunit A , CAF-I 150 kDa subunit , CAF-I p150 , chromatin assembly factor 1 subunit A , chromatin assembly factor I (150 kDa) , chromatin assembly factor I p150 subunit , hp150 , CAF-Ip150 , chromatin assembly factor-1p150 , Chromatin assembly factor I p150 subunit , CAF-I 150 kDa subunit B , CAF-I p150-B , CAF-Ip150-B , Chromatin assembly factor I p150 subunit B , chromatin assembly factor 1 subunit A-B

GENE ID SPEZIES
363333 Rattus norvegicus
455603 Pan troglodytes
485038 Canis lupus familiaris
100231993 Taeniopygia guttata
100447657 Pongo abelii
100590477 Nomascus leucogenys
10036 Homo sapiens
27221 Mus musculus
504535 Bos taurus
770217 Gallus gallus
563212 Danio rerio
733264 Xenopus laevis
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