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The protein encoded by CCR9 is a member of the beta chemokine receptor family. Zusätzlich bieten wir Ihnen Chemokine (C-C Motif) Receptor 9 Antikörper (297) und Chemokine (C-C Motif) Receptor 9 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
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study found that the inflammatory chemokine (zeige CCL1 ELISA Kits) CCL5 (zeige CCL5 ELISA Kits) is mostly retained (75%) during the resolution of zymosan A peritonitis in mice; CCL5 (zeige CCL5 ELISA Kits) exerts a novel proresolving role on macrophages when acting in concert with apoptotic PMN (zeige TBCE ELISA Kits)-expressed D6.
CCR9 and CCL25 (zeige CCL25 ELISA Kits) expressions are induced in the early stages of airway inflammation and they have an important role modulating eosinophils and lymphocytes recruitment at the first stages of inflammatory process
CCR9 and Integrin-beta7 expression has a differential effect on graft fate during acute graft-versus-host disease (GVHD) of the liver depending on the GVHD target tissue.
data indicate that in addition to acting as a gut (zeige GUSB ELISA Kits)-homing molecule, CCR9 signaling shapes immune responses by inhibiting Treg cell development
Data suggest that blocking CC chemokine receptor 9 (CCR9) may represent a novel safe therapy for rheumatoid arthritis (RA).
activation of Notch1 (zeige NOTCH1 ELISA Kits) has a dominant-negative effect on Ccr9 transcription and that Notch1 (zeige NOTCH1 ELISA Kits) and E proteins control the dynamic expression of Ccr9 during T cell development.
ACKR2 can regulate fetal (zeige CCL1 ELISA Kits) growth, placental structure, and neonatal mortality in mice.
Further examination revealed that proximity of pro-lymphangiogenic macrophages to developing lymphatic vessel surfaces is increased in ACKR2-deficient mice and reduced in CCR2-deficient mice.
some cells, including plasmacytoid dendritic cells, can express both CCR2 (zeige CCR2 ELISA Kits) and ACKR2; that Ly6C(high) monocytes have particularly strong CCL2 (zeige CCL2 ELISA Kits)-scavenging potential in vitro and in vivo; and that CCR2 (zeige CCR2 ELISA Kits) is a much more effective CCL2 (zeige CCL2 ELISA Kits) scavenger than ACKR2.
CCR9/CCL25 (zeige CCL25 ELISA Kits) is involved in acute skin transplantation rejection and anti-CCL25 (zeige CCL25 ELISA Kits) strategies might be useful in preventing acute rejection.
this study showed that CCR7 (zeige CCR7 ELISA Kits) are overexpressed in CD4 (zeige CD4 ELISA Kits)(-) CD8 (zeige CD8A ELISA Kits)(-) thymocytes of myasthenia gravis patients.
Results indicated that the expression levels of CCR9 in lesional skin may be a useful biologic marker of the clinical efficacy of infliximab therapy in psoriasis patients.
Xray crystal structure of the CCR9 receptor in complex with vercirnon at 2.8 A resolution
that CCL25 (zeige CCL25 ELISA Kits)/CCR9 signal may provide cancer cells with chemotactic abilities through influencing several epithelial-mesenchymal transitionmarkers
Studies indicate important roles played by chemokine ligand 25 (CCL25 (zeige CCL25 ELISA Kits))/chemokine receptor 9 (CCR9) in tumorigenesis, tumor chemoresistance and metastasis.
CCR9 mRNA and protein levels were significantly increased in the nasopharyngeal carcinoma group compared with the control group.
CCR9-CCL25 (zeige CCL25 ELISA Kits) interaction promoted proliferation and suppressed apoptosis of non-small cell lung cancer cells by activating the PI3K (zeige PIK3CA ELISA Kits)/Akt (zeige AKT1 ELISA Kits) pathway.
CCR9 could be beneficial in predicting lymph node metastasis, and it might act as a novel prognostic biomarker for lung adenocarcinoma.
We also show that primary tumors can be modeled in immunocompetent mice by microinjecting CCR9-expressing cancer cell lines into early-stage mouse blastocysts, which induces central immune tolerance
The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described. Multiple transcript variants encoding different isoforms have been found for this gene.
C-C chemokine receptor type 9
, G protein-coupled receptor 28
, C-C CKR-9
, chemokine C-C receptor 10
, chemokine C-C motif receptor 9