Chemokine (C-C Motif) Ligand 17 Proteine (CCL17)

CCL17 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Zusätzlich bieten wir Ihnen CCL17 Antikörper (187) und CCL17 Kits (65) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CCL17 6361 Q92583
CCL17 20295  
CCL17 117518  
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Top CCL17 Proteine auf antikoerper-online.de

Showing 10 out of 51 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 56 bis 61 Tage
5.753,97 €
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Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 56 bis 61 Tage
8.202,81 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert 4 pack Anmelden zum Anzeigen 6 bis 8 Tage
82,82 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert   10 μg Anmelden zum Anzeigen 6 bis 8 Tage
98,35 €
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HOST_Escherichia coli (E. coli) Maus Unkonjugiert   10 μg Anmelden zum Anzeigen 6 bis 8 Tage
108,71 €
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HOST_Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 11 bis 15 Tage
303,81 €
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HOST_Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
640,00 €
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HOST_Escherichia coli (E. coli) Maus His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
688,57 €
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HOST_Escherichia coli (E. coli) Ratte His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
716,19 €
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CCL17 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, ,
Mouse (Murine) , ,
,
Rat (Rattus)

Am meisten referenzierte CCL17 Proteine

  1. Mouse (Murine) CCL17 Protein expressed in Escherichia coli (E. coli) - ABIN2666602 : Stutte, Quast, Gerbitzki, Savinko, Novak, Reifenberger, Homey, Kolanus, Alenius, Förster: Requirement of CCL17 for CCR7- and CXCR4-dependent migration of cutaneous dendritic cells. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Zeige alle 6 Referenzen für 2666602

  2. Human CCL17 Protein expressed in Escherichia coli (E. coli) - ABIN2667385 : Oo, Weston, Lalor, Curbishley, Withers, Reynolds, Shetty, Harki, Shaw, Eksteen, Hubscher, Walker, Adams: Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Zeige alle 5 Referenzen für 2667385

  3. Human CCL17 Protein expressed in Escherichia coli (E. coli) - ABIN2666600 : Yogo, Fujishima, Inoue, Saito, Shiomi, Yamaguchi, Ishizaka: Macrophage derived chemokine (CCL22), thymus and activation-regulated chemokine (CCL17), and CCR4 in idiopathic pulmonary fibrosis. in Respiratory research 2009 (PubMed)
    Zeige alle 5 Referenzen für 2666600

  4. Human CCL17 Protein expressed in Escherichia coli (E. coli) - ABIN666786 : Imai, Yoshida, Baba, Nishimura, Kakizaki, Yoshie: Molecular cloning of a novel T cell-directed CC chemokine expressed in thymus by signal sequence trap using Epstein-Barr virus vector. in The Journal of biological chemistry 1996 (PubMed)
    Zeige alle 2 Referenzen für 666786

Weitere Proteine zu Chemokine (C-C Motif) Ligand 17 (CCL17) Interaktionspartnern

Human Chemokine (C-C Motif) Ligand 17 (CCL17) Interaktionspartner

  1. Low CCL17 expression is a potential independent adverse prognostic biomarker for recurrence and survival of patients with clear cell renal cell carcinoma (zeige MOK Proteine) after nephrectomy.

  2. IP-10 (zeige CXCL10 Proteine) serum increase or TARC/IP-10 (zeige CXCL10 Proteine) ratio decrease along with abnormal hepatic enzymatic alteration could signify early rejection of the transplanted liver.

  3. elevated pre-treatment levels of sGal-1, sCD163 (zeige CD163 Proteine), sCD30 and TARC can be found in patients with classic Hodgkin lymphoma. However, only plasma TARC accurately reflects disease activity and correlates with clinical treatment response.

  4. levels elevated in rheumatoid arthritis synovial fluid, due to production by mononuclear cells, particularly CD1c (zeige CD1C Proteine) classical dendritic cells

  5. Serum TARC levels are well correlated with blood eosinophil counts in patients with generalized drug eruptions, indicating that Th2-type immune reactions underlie TARC production. Serum TARC measurements also have potent diagnostic value for DIHS, with high sensitivity and specificity.

  6. Data suggest that Th1 (zeige TH1L Proteine) (IFN-gamma (zeige IFNG Proteine)-inducible protein-10 IP-10/CXCL10 (zeige CXCL10 Proteine)) and Th2 (thymus and activation regulated chemokine TARC/CCL17) and (macrophage derived chemokine MDC/CCL22 (zeige CCL22 Proteine)) cooperatively play a role in the development of ankylosing spondylitis (AS).

  7. CCL17 positively regulates the tumorigenesis of hepatocellular carcinoma.Higher levels of intratumoral CCL17 expression are associated with poorer survival of hepatocellular carcinoma patients.

  8. CCL17 and CCL18 (zeige CCL18 Proteine) dermal expression is associated with leprosy polarity.

  9. The SNP rs223895 in TARC/CCL17 gene is associated with the susceptibility to Kawasaki disease.

  10. Serum CCL17 levels are associated with coronary artery disease and atherosclerosis severity independently of traditional cardiovascular risk factors.

Mouse (Murine) Chemokine (C-C Motif) Ligand 17 (CCL17) Interaktionspartner

  1. the M2 macrophage chemokine CCL17 was identified as an essential factor for enhanced survival in the absence of CB2, because CCL17 x Cnr2 double-deficient mice were fully susceptible to experimental cerebral malaria.

  2. Aged mice had similar levels of IL-1beta (zeige IL1B Proteine), TNF (zeige TNF Proteine), IFN-gamma (zeige IFNG Proteine), IL-17 (zeige IL17A Proteine), and granulocyte colony-stimulating factor (zeige CSF3 Proteine) following S. pneumoniae infection, compared with young mice, but increased levels of the chemokines CXCL9 (zeige CXCL9 Proteine), CXCL12 (zeige CXCL12 Proteine), CCL3 (zeige CCL3 Proteine), CCL4 (zeige CCL4 Proteine), CCL5 (zeige CCL5 Proteine), CCL11, and CCL17.

  3. that effective engagement of CCR4 (zeige CCR4 Proteine) by CCL17 involves two distinct binding domains and interaction with both is required for signaling

  4. murine tumor-associated neutrophils secrete significant amounts of CCL17. Migration assays showed recruitment of T-regs by tumor-associated neutrophils, which was inhibited with anti-CCL17 monoclonal antibodies.

  5. TSLP (zeige TSLP Proteine) activated a subset of CD11b (zeige ITGAM Proteine)(+) DCs in the skin to produce CCL17, upregulate CCR7 (zeige CCR7 Proteine), and migrate to the draining lymph node to initiate Th2 differentiation.

  6. CCL17 is required for induction of intestinal inflammation in mice and has an autocrine effect on dendritic cells that promotes production of inflammatory cytokines and activation of Th1 (zeige HAND1 Proteine) and Th17 cells and reduces expansion of Treg cells.

  7. Kinetics of CCL17 mRNA expression in an allergic contact dermatitis model.

  8. Thymus and activation-regulated chemokine (TARC)/CC chemokine (zeige CCL1 Proteine) ligand (CCL) 17 accelerates wound healing by enhancing fibroblast migration.

  9. Data identify DC-derived CCL17 as a central regulator of Treg homeostasis, implicate DCs and their effector functions in atherogenesis, and suggest that CCL17 might be a target for vascular therapy.

  10. Data show that mice deficient for CCL17 had an up to 4-fold higher worm burden compared with controls by day 10 of infection with the murine filaria Litomosoides sigmodontis.

CCL17 Protein Überblick

Protein Überblick

This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.

Genbezeichner und Symbole assoziert mit CCL17

  • chemokine (C-C motif) ligand 17 (CCL17)
  • chemokine (C-C motif) ligand 17 (Ccl17)
  • A-152E5.3 Protein
  • Abcd-2 Protein
  • CCL17 Protein
  • Scya17 Protein
  • Scya17l Protein
  • Tarc Protein

Bezeichner auf Proteinebene für CCL17

chemokine (C-C motif) ligand 17 , C-C motif chemokine 17 , CC chemokine TARC , T cell-directed CC chemokine , small inducible cytokine subfamily A (Cys-Cys), member 17 , small-inducible cytokine A17 , thymus and activation-regulated chemokine , small inducible cytokine subfamily A17 , chemokine ligand 17-like protein , chemokine CCL17/TARC , small inducible cytokine A17

GENE ID SPEZIES
467985 Pan troglodytes
6361 Homo sapiens
20295 Mus musculus
493832 Felis catus
100140488 Bos taurus
403586 Canis lupus familiaris
415652 Gallus gallus
100715805 Cavia porcellus
780408 Sus scrofa
117518 Rattus norvegicus
101120186 Ovis aries
574180 Macaca mulatta
Ausgewählte Anbieter für CCL17 Proteine (CCL17)
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