Chemokine (C Motif) Receptor 1 Proteine (XCR1)

The protein encoded by XCR1 is a chemokine receptor belonging to the G protein-coupled receptor superfamily. Zusätzlich bieten wir Ihnen XCR1 Antikörper (90) und XCR1 Kits (18) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
XCR1 2829 P46094
XCR1 23832  
Ratte XCR1 XCR1 301086  
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Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 46 bis 51 Tage
5.743,80 €
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HOST_Wheat germ Human Unkonjugiert   2 μg Anmelden zum Anzeigen 7 bis 8 Tage
406,59 €
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HOST_Escherichia coli (E. coli) Maus T7 tag,His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
670,48 €
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XCR1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,

Mouse (Murine)

Weitere Proteine zu Chemokine (C Motif) Receptor 1 (XCR1) Interaktionspartnern

Cow (Bovine) Chemokine (C Motif) Receptor 1 (XCR1) Interaktionspartner

  1. The distribution characters of cattle XCR1 and XCL1 (zeige XCL1 Proteine) suggested a vital role in regulation of acquired immune responses and indicated a potential for a DC targeted veterinary vaccine in cattle using XCL1 (zeige XCL1 Proteine) fused antigens.

Rhesus Monkey Chemokine (C Motif) Receptor 1 (XCR1) Interaktionspartner

  1. The complete cDNA sequence of XCR1 was obtained, containing 415 bp 5'UTR, 1003 bp coding region and 248 bp 3'UTR.

  2. TLR3 (zeige TLR3 Proteine)-responsive, XCR1+, CD141(BDCA-3 (zeige THBD Proteine))+/CD8alpha+-equivalent dendritic cells uncovered in healthy and simian immunodeficiency virus-infected rhesus macaques.

Human Chemokine (C Motif) Receptor 1 (XCR1) Interaktionspartner

  1. Demonstrate equivalence between human and mouse XCR1(+) dendritic cells and human and mouse Langerhans cells.

  2. results indicate that XCR1 is a new potential therapeutic target for the treatment of lung cancer bone metastasis

  3. Induction of potent CD8 (zeige CD8A Proteine) T cell cytotoxicity by specific targeting of antigen to cross-presenting dendritic cells in vivo via murine or human XCR1.

  4. XCR1 is expressed early during the course of tumorigenic transformation and contributes towards increased cell migration and proliferation, which can facilitate the prometastatic behavior of epithelial ovarian cancer cells.

  5. CD8alpha-positive dendritic cells (DCs) and CD103 (zeige ITGAE Proteine)-positive DCs belong to a common DC subset which is unequivocally identified by XCR1 transgene expression despite their different anatomical locations.

  6. Our findings argue against the hypothesis that genetic variability in the G-Protein-Coupled Receptor Kinase 5 and Casein Kinase 2 genes modifies Parkinson disease susceptibility

  7. XCR1 expression and biased VH gene usage are distinct features of diffuse large B-cell lymphoma initially manifesting in the bone marrow.

  8. The expression patterns of XCR1 and XCL1 (zeige XCL1 Proteine) were conserved in human and mice blood cells, including certain dendritic cell subsets.

  9. CD141 (zeige THBD Proteine)+ dendritic cells are the only cells in human blood that express the chemokine receptor (zeige CCR1 Proteine) XCR1 and respond to the specific ligand XCL1 (zeige XCL1 Proteine) by Ca2 (zeige CA2 Proteine)+ mobilization and potent chemotaxis.

  10. XCR1 constitutes the first conserved specific marker for cell subsets homologous to mouse CD8alpha+ dendritic cells in higher vertebrates.

Mouse (Murine) Chemokine (C Motif) Receptor 1 (XCR1) Interaktionspartner

  1. The interaction between XCL1 (zeige XCL1 Proteine) and XCR1 plays a crucial role in the classical immunology response.

  2. Data show that mice lacking either XCL1 (zeige XCL1 Proteine) or XCR1 exhibit similar specific defects in intestinal T cell populations as XCR1-dendritic cells (DC)-deficient mice. Therefore it is possible that the XCR1-XCL1 (zeige XCL1 Proteine) axis itself is directly involved in intestinal T cell homeostasis, via a mechanism that might either involve interaction with XCR1+ DCs or be independent of this pathway.

  3. Demonstrate equivalence between human and mouse XCR1(+) dendritic cells and human and mouse Langerhans cells.

  4. Vaccine molecules targeting Xcr1 on cross-presenting DCs induce protective CD8 (zeige CD8A Proteine)+ T-cell responses against influenza virus.

  5. Induction of potent CD8 (zeige CD8A Proteine) T cell cytotoxicity by specific targeting of antigen to cross-presenting dendritic cells in vivo via murine or human XCR1.

  6. The expression patterns of XCR1 and XCL1 (zeige XCL1 Proteine) were conserved in human and mice blood cells, including certain dendritic cell subsets.

  7. XCR1 constitutes the first conserved specific marker for cell subsets homologous to mouse CD8alpha+ dendritic cells in higher vertebrates.

XCR1 Protein Überblick

Protein Überblick

The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Genbezeichner und Symbole assoziert mit XCR1

  • chemokine (C motif) receptor 1 (XCR1)
  • chemokine (C motif) receptor 1 (xcr1a)
  • chemokine (C motif) receptor 1 (Xcr1)
  • XC chemokine receptor 1 (LOC100352332)
  • Ccxcr1 Protein
  • CCXCR1-L Protein
  • Gpr5 Protein
  • mXcr1 Protein
  • XCR1 Protein

Bezeichner auf Proteinebene für XCR1

chemokine XC receptor 1 , chemokine C motif receptor 1 , CCXC chemokine receptor 1 like , XC chemokine receptor 1 , chemokine (C motif) receptor 1 , G protein-coupled receptor 5 , G-protein coupled receptor 5 , chemokine (C motif) XC receptor 1 , lymphotactin receptor , C motif-1/lymphotactin receptor , SCM1 receptor

GENE ID SPEZIES
414375 Sus scrofa
428452 Gallus gallus
460321 Pan troglodytes
484792 Canis lupus familiaris
553500 Danio rerio
617880 Bos taurus
713622 Macaca mulatta
100579780 Nomascus leucogenys
2829 Homo sapiens
23832 Mus musculus
301086 Rattus norvegicus
100352332 Oryctolagus cuniculus
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