Charged Multivesicular Body Protein 5 (CHMP5) ELISA Kits

CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. Zusätzlich bieten wir Ihnen CHMP5 Antikörper (58) und CHMP5 Proteine (13) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Human CHMP5 CHMP5 51510 Q9NZZ3
Anti-Maus CHMP5 CHMP5 76959 Q9D7S9
Anti-Ratte CHMP5 CHMP5 297995 Q4QQV8
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Weitere ELISA Kits für CHMP5 Interaktionspartner

Human Charged Multivesicular Body Protein 5 (CHMP5) Interaktionspartner

  1. CHMP5 might be involved in the homeostatic regulation of TCR on the cell surface, presumably through TCR recycling or degradation. Thus CHMP5 is implicated in TCR-mediated signaling.

  2. ESCRT-III protein CHMP5 inhibits LIP5-mediated VPS4 activation by inducing a moderate conformational change within LIP5.

  3. after CHMP5 inhibition, both Granzyme B (zeige Gzmb ELISA Kits)/Perforin (zeige PRF1 ELISA Kits) apoptotic pathway and apoptosis-inducing factor (zeige AIFM1 ELISA Kits)-mediated necrotic pathway were activated, while autophagic pathway was not activated

  4. PNAS-2 was shown to be anti-apoptotic and may participate in leukemogenesis

  5. pnas-2 is specifically up-regulated in acute leukemia patients.

  6. The pnas-2 gene may be closely related with apotosis of arsenic sulfide treated APL (zeige FASL ELISA Kits) cells.

Mouse (Murine) Charged Multivesicular Body Protein 5 (CHMP5) Interaktionspartner

  1. CHMP5 is a key sensor of thresholds for signaling via the T cell antigen receptor (TCR) that is essential for T cell development. CHMP5 enabled positive selection by promoting post-selection thymocyte survival in part through stabilization of the pro-survival protein Bcl-2 (zeige BCL2 ELISA Kits).

  2. CHMP5 tunes NF-kappaB (zeige NFKB1 ELISA Kits) signaling downstream of RANK in osteoclasts to dampen osteoclast differentiation, osteoblast coupling and bone turnover rates.

  3. CHMP5 regulates late endosome function downstream of MVB formation, and the loss of CHMP5 enhances signal transduction by inhibiting lysosomal degradation of activated receptors.

CHMP5 Antigen-Profil

Beschreibung des Gens

CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006

Genbezeichner und Symbole assoziert mit CHMP5

  • charged multivesicular body protein 5 (chmp5-b) Antikörper
  • charged multivesicular body protein 5b (chmp5b) Antikörper
  • charged multivesicular body protein 5 (CHMP5) Antikörper
  • charged multivesicular body protein 5 (chmp5-a) Antikörper
  • charged multivesicular body protein 5 (chmp5) Antikörper
  • chromatin modifying protein 5 (chmp5) Antikörper
  • chromatin modifying protein 5 (LOC100345211) Antikörper
  • charged multivesicular body protein 5 (Chmp5) Antikörper
  • 2210412K09Rik Antikörper
  • AW545668 Antikörper
  • C9orf83 Antikörper
  • cgi-34 Antikörper
  • chmp5 Antikörper
  • HSPC177 Antikörper
  • PNAS-2 Antikörper
  • RGD1305968 Antikörper
  • SNF7DC2 Antikörper
  • Vps60 Antikörper
  • zgc:64125 Antikörper

Bezeichner auf Proteinebene für CHMP5

chromatin modifying protein 5 , charged multivesicular body protein 5 , chromatin-modifying protein 5 , Chromatin-modifying protein 5 , Charged multivesicular body protein 5 , SNF7 domain containing 2 , SNF7 domain-containing protein 2 , apoptosis-related protein PNAS-2 , hVps60 , vacuolar protein sorting-associated protein 60 , likely ortholog of H. sapiens SNF7 domain containing 2

GENE ID SPEZIES
380303 Xenopus laevis
393351 Danio rerio
420968 Gallus gallus
446761 Xenopus laevis
549502 Xenopus (Silurana) tropicalis
703191 Macaca mulatta
746713 Pan troglodytes
100172361 Pongo abelii
100305259 Oncorhynchus mykiss
100345211 Oryctolagus cuniculus
100528648 Ictalurus punctatus
51510 Homo sapiens
539781 Bos taurus
76959 Mus musculus
297995 Rattus norvegicus
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