Chaperonin Containing TCP1, Subunit 5 (Epsilon) Proteine (CCT5)

The protein encoded by CCT5 is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). Zusätzlich bieten wir Ihnen CCT5 Antikörper (77) und CCT5 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CCT5 22948 P48643
Ratte CCT5 CCT5 294864 Q68FQ0
CCT5 12465 P80316
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$7,759.50
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$7,759.50
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$785.40
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CCT5 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Chaperonin Containing TCP1, Subunit 5 (Epsilon) (CCT5) Interaktionspartnern

Human Chaperonin Containing TCP1, Subunit 5 (Epsilon) (CCT5) Interaktionspartner

  1. CCT5 complex caps (zeige CAPS Proteine) mutant mHTT fibrils at their tips and encapsulates mHTT oligomers, providing a structural description of the inhibition of mHTTQ46-Ex1 (zeige FRMD6 Proteine) by CCT5 complex and a shared mechanism of mHTT inhibition between TRiC (zeige MARVELD2 Proteine) chaperonin (zeige HSPD1 Proteine) and the CCT5 complex

  2. H147R CCT5 was not as efficient in chaperoning these substrates as wild type CCT5.

  3. Both CCT4 (zeige CCT4 Proteine) and CCT5 homo-oligomers have the property of forming 8-fold double rings absent the other subunits, and these complexes carry out chaperonin (zeige HSPD1 Proteine) reactions without other partner subunits.

  4. introduction of the truncated human CCT epsilon subunit (zeige CHRNE Proteine) into yeast cells

  5. A missense mutation within the CCT5 gene is associated with autosomal recessive mutilating sensory neuropathy with spastic paraplegia.

  6. mRNA expression of CCT5, RGS3 (zeige RGS3 Proteine), and YKT6 (zeige YKT6 Proteine) was significantly up-regulated in p53 (zeige TP53 Proteine)-mutated tumors and associated with a low response rate to docetaxel.

CCT5 Protein Überblick

Protein Überblick

The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. In addition, three pseudogenes of this gene have been identified.

Genbezeichner und Symbole assoziert mit CCT5

  • chaperonin containing TCP1 subunit 5 (CCT5)
  • chaperonin containing TCP1 subunit 5 (Cct5)
  • chaperonin containing TCP1, subunit 5 (epsilon) (cct5)
  • chaperonin containing TCP1, subunit 5 (epsilon) (Cct5)
  • chaperonin containing TCP1, subunit 5 (epsilon) (CCT5)
  • chaperonin containing TCP1 subunit 5 S homeolog (cct5.S)
  • Chaperonin Containing TCP-1 (cct-5)
  • T-complex protein 1 subunit epsilon (LOC100632800)
  • chaperonin containing Tcp1, subunit 5 (epsilon) (Cct5)
  • CCT-epsilon Protein
  • Cct5 Protein
  • cct5a Protein
  • Ccte Protein
  • DKFZp469K0732 Protein
  • mKIAA0098 Protein
  • TCP-1-epsilon Protein
  • TCPE Protein
  • wu:fb54h08 Protein

Bezeichner auf Proteinebene für CCT5

T-complex protein 1 subunit epsilon , T-complex protein 1, epsilon subunit , CCT-epsilon , TCP-1-epsilon , chaperonin subunit 5 (epsilon) , TCP-1 epsilon , chaperonin containing TCP1, subunit 5 (epsilon) , chaperonin containing TCP1, subunit 5 (epsilon) a , T-complex protein 1 subunit epsilon-like , t-complex protein 1 subunit epsilon-like

GENE ID SPEZIES
22948 Homo sapiens
294864 Rattus norvegicus
322258 Danio rerio
420930 Gallus gallus
461721 Pan troglodytes
696640 Macaca mulatta
533784 Bos taurus
100169634 Acyrthosiphon pisum
606873 Canis lupus familiaris
100101123 Felis catus
100171594 Pongo abelii
380145 Xenopus laevis
100013512 Monodelphis domestica
100409570 Callithrix jacchus
100483094 Ailuropoda melanoleuca
175588 Caenorhabditis elegans
100070912 Equus caballus
100539807 Meleagris gallopavo
100627652 Sus scrofa
100632800 Amphimedon queenslandica
12465 Mus musculus
100733395 Cavia porcellus
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