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The protein encoded by CDC27 shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.
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Dog (Canine) Monoclonal CDC27 Primary Antibody für IF, IP - ABIN967980
Kramer, Scheuringer, Podtelejnikov, Mann, Peters: Mitotic regulation of the APC activator proteins CDC20 and CDH1. in Molecular biology of the cell 2000
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Human Monoclonal CDC27 Primary Antibody für IHC, ELISA - ABIN969035
Goto, Eddy: Speriolin is a novel spermatogenic cell-specific centrosomal protein associated with the seventh WD motif of Cdc20. in The Journal of biological chemistry 2004
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Dog (Canine) Polyclonal CDC27 Primary Antibody für EIA, WB - ABIN401299
Gabellini, Colaluca, Vodermaier, Biamonti, Giacca, Falaschi, Riva, Peverali: Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression. in The EMBO journal 2003
Data indicate that UBE2S and APC3 co-regulate the expression level of P21 at G2/M check point via the ubiquitin-proteasome system.
Cdc27 is a novel binding partner of Elmo1 (zeige ELMO1 Antikörper).Cdc27-Elmo1 (zeige ELMO1 Antikörper) has a cellular role independent from the Elmo-Dock1 (zeige DOCK1 Antikörper)-Rac (zeige AKT1 Antikörper) signal module.
miR (zeige MLXIP Antikörper)-27a could modulate proliferation and radiosensitivity of TNBC cells. CDC-27 is a direct target of miR (zeige MLXIP Antikörper)-27a and its downregulation conferred increased radioresistance of the cells.
These findings suggested that polymorphisms in cdc27 may contribute to the susceptibility of BC though functional studies are needed to further elucidate the underling mechanisms of the associations
The structures show how one APC16 binds asymmetrically to the symmetric APC3 dimer and, together with biochemistry and prior data, explain how APC16 recruits APC7 (zeige ANAPC7 Antikörper) to APC3.
Low cdc27 and high securin (zeige PTTG1 Antikörper) expression predict short survival for breast cancer patients.
Down-regulation of CDC27 protein is associated with radiation resistance.
Data indicate that additional density present in the anaphase-promoting complex (APC (zeige APC Antikörper)/C) structure, proximal to Apc3/Cdc27 of the (tetratricopeptide repeat) lobe, is assigned to the TPR subunit Apc7 (zeige ANAPC7 Antikörper), a subunit specific to vertebrate APC (zeige APC Antikörper)/C.
the biochemical, structural, and cellular determinants of the novel interaction between MCPH1 (zeige MCPH1 Antikörper) and Cdc27 and suggest that this interaction may occur within the larger context of MCPH1 (zeige MCPH1 Antikörper)-APC (zeige APC Antikörper)/C.
phosphorylation of Cdc27 by CKII (zeige CSNK2A1 Antikörper) is involved in TGF-beta (zeige TGFB1 Antikörper)-induced activation of APC (zeige APC Antikörper).
Cdc27 directs cyclin D1 (zeige CCND1 Antikörper) to alternative degradation by anaphase promoting complex/cyclosome.
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
cell division cycle 27 homolog (S. cerevisiae)
, cell division cycle 27 homolog
, cell division cycle protein 27 homolog
, CDC27 homolog
, anaphase promoting complex subunit 3
, anaphase-promoting complex subunit 3
, anaphase-promoting complex, protein 3
, nuc2 homolog