anti-Cell Death-Inducing DFFA-Like Effector A (CIDEA) Antikörper

CIDEA encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. Zusätzlich bieten wir Ihnen CIDEA Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CIDEA 1149 O60543
CIDEA 12683 O70302
CIDEA 291541  
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Showing 10 out of 98 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB CIDEA Antibody (C-term) (ABIN657978) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the CIDEA antibody detected the CIDEA protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, IHC (p), WB Western Blot: CIDEA Antibody [NBP1-76950] - Mouse heart tissue lysate with CIDE-A antibody at 1:500 dilution. Immunohistochemistry-Paraffin: CIDEA Antibody [NBP1-76950] - Mouse heart tissue with CIDE-A antibody at 5 ug/ml. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
341,00 €
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Maus Kaninchen Unkonjugiert IHC (p), WB 0.1 mg Anmelden zum Anzeigen 4 bis 5 Tage
283,41 €
Details
Human Maus Unkonjugiert IP, ELISA, WB Immunoprecipitation of CIDEA transfected lysate using anti-CIDEA monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with CIDEA MaxPab rabbit polyclonal antibody. Western Blot analysis of CIDEA expression in transfected 293T cell line by CIDEA monoclonal antibody (M01), clone 4B9.Lane 1: CIDEA transfected lysate(28.3 KDa).Lane 2: Non-transfected lysate. 100 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
517,00 €
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Human Kaninchen Unkonjugiert IHC (p), WB 50 μg Anmelden zum Anzeigen 8 bis 10 Tage
456,00 €
Details
Maus Kaninchen Unkonjugiert IHC, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
635,55 €
Details
Human Kaninchen Unkonjugiert IF, WB Immunofluorescence analysis of A549 cell using CIDEA antibody. Blue: DAPI for nuclear staining. Immunofluorescence analysis of A549 cell using CIDEA antibody. 100 μL Anmelden zum Anzeigen 12 Days
261,90 €
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, IHC (p), WB Western Blot: CIDEA Antibody [NBP1-76951] - Human brain tissue lysate in the absence (A) or presence (B) of peptide (2085P) with CIDE-A antibody at 1:2000 dilution. Immunohistochemistry-Paraffin: CIDEA Antibody [NBP1-76951] - Human brain tissue with CIDE-A antibody at 5 ug/ml. 0.1 mg Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
Details
Maus Kaninchen Unkonjugiert ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 15 Tage
377,14 €
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CIDEA Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-CIDEA Antikörper

  1. Human Monoclonal CIDEA Primary Antibody für IP, ELISA - ABIN514417 : Puri, Ranjit, Konda, Nicoloro, Straubhaar, Chawla, Chouinard, Lin, Burkart, Corvera, Perugini, Czech: Cidea is associated with lipid droplets and insulin sensitivity in humans. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
    Zeige alle 4 Referenzen für 514417

  2. Human Polyclonal CIDEA Primary Antibody für WB - ABIN657978 : Laurencikiene, Stenson, Arvidsson Nordström, Agustsson, Langin, Isaksson, Permert, Rydén, Arner: Evidence for an important role of CIDEA in human cancer cachexia. in Cancer research 2008 (PubMed)

  3. Human Polyclonal CIDEA Primary Antibody für ELISA, ICC - ABIN4298761 : Rohm, Schäfer, Laurent, Üstünel, Niopek, Algire, Hautzinger, Sijmonsma, Zota, Medrikova, Pellegata, Ryden, Kulyte, Dahlman, Arner, Petrovic, Cannon, Amri, Kemp, Steinberg, Janovska, Kopecky, Wolfrum et al.: An AMP-activated protein kinase-stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice. ... in Nature medicine 2016 (PubMed)

  4. Mouse (Murine) Polyclonal CIDEA Primary Antibody für IHC (p), WB - ABIN2472992 : Inohara, Koseki, Chen, Wu, Núñez: CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor. in The EMBO journal 1998 (PubMed)

Weitere Antikörper gegen CIDEA Interaktionspartner

Human Cell Death-Inducing DFFA-Like Effector A (CIDEA) Interaktionspartner

  1. Cidea, unexpectedly, functions molecularly as an indirect inhibitor of thermogenesis via inhibition of UCP1 (zeige UCP1 Antikörper) activity.

  2. These data establish a functional role for Cidea and suggest that, in humans, the association between Cidea levels in white fat and metabolic health is not only correlative but also causative.

  3. Since Cide-A protein plays a role in the development of metabolic diseases such as obesity, metabolic syndrome, type 2 diabetes and their vascular complications, CIDE -A gene and protein are potential therapeutic targets for these diseases.

  4. The lowest mean relative of the gene expression for CIDE-A was observed in the group of obese patients with aortic aneurysm and lipid disorders

  5. the association of tag-single nucleotide polymorphisms and haplotype structures of the CIDEA gene with obesity in a Han Chinese population, was investigated.

  6. CIDE proteins expression correlate with tumor and survival characteristics in patients with renal cell carcinoma (zeige MOK Antikörper).

  7. Insulin (zeige INS Antikörper) regulates CIDEA and CIDEC (zeige CIDEC Antikörper) expression via PI3K (zeige PIK3CA Antikörper), and it regulates expression of each protein via Akt1 (zeige AKT1 Antikörper)/2-and JNK2 (zeige MAPK9 Antikörper)-dependent pathways, respectively, in human adipocytes.

  8. The proportion of subjects with CIDEA) gene V115F (G/T) polymorphism with phenotypes of metabolic syndrome in a Chinese population was significantly higher based on genotype, in the order: GG

  9. CIDEA binds to liver X receptors and regulates their activity in vitro.

  10. These data indicate that the carboxy-terminal domain of Cidea directs lipid droplet targeting, lipid droplet clustering, and triglyceride accumulation, whereas the amino terminal domain is required for Cidea-mediated development of enlarged lipid droplets

Mouse (Murine) Cell Death-Inducing DFFA-Like Effector A (CIDEA) Interaktionspartner

  1. results suggest that FSP27beta negatively regulates CideA-promoted enlargement of lipid droplet size in brown adipocytes.

  2. The authors show demonstrate an essential role of an amphipathic helix in CIDEA, which facilitates embedding in the lipid droplet phospholipid monolayer and binds phosphatidic acid (PA).

  3. Data (including data from studies in knockout mice) suggest Cideb (zeige CIDEB Antikörper) promotes lipid storage as droplets in hepatocytes under normal diet conditions; Cidea/Cidec (zeige CIDEC Antikörper) promote fusion of lipid droplets leading to liver steatosis in fasting (16h) and obese mice.

  4. Cidea is highly associated with adiposity and insulin (zeige INS Antikörper) resistance, whereas Cidec (zeige CIDEC Antikörper) is related to insulin (zeige INS Antikörper) sensitivity

  5. data reveal an important role of Cidea in controlling lipid droplet fusion, lipid storage in brown and white adipose tissue, and the development of obesity

  6. maternal diet modulates the age-associated changes in Cidea expression leading to the development of fatty liver

  7. Cidea is a crucial regulator of sebaceous gland lipid storage and sebum lipid secretion in mice.

  8. acts as transcriptional coactivator of C/EBPbeta (zeige CEBPB Antikörper) in mammary glands to control lipid secretion

  9. Cidea is a critical regulator of free fatty acid-induced apoptosis as a novel downstream target for Foxo1 (zeige FOXO1 Antikörper) in pancreatic beta-cells

  10. These data indicate that the carboxy-terminal domain of Cidea directs lipid droplet targeting, lipid droplet clustering, and triglyceride accumulation, whereas the amino terminal domain is required for Cidea-mediated development of enlarged lipid droplets

Cow (Bovine) Cell Death-Inducing DFFA-Like Effector A (CIDEA) Interaktionspartner

  1. These results suggest that CIDE-A and UCP1 (zeige UCP1 Antikörper) are regulated by insulin (zeige INS Antikörper) and/or fatty acids in mammary epithelial cells and lactating mammary glands, and thereby play an important role in lipid and energy metabolism.

CIDEA Antigen-Profil

Protein Überblick

This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.

Genbezeichner und Symbole assoziert mit CIDEA

  • cell death-inducing DFFA-like effector a (CIDEA) Antikörper
  • cell death-inducing DNA fragmentation factor, alpha subunit-like effector A (Cidea) Antikörper
  • cell death-inducing DFFA-like effector a (Cidea) Antikörper
  • cell death-inducing DFFA-like effector a (cidea) Antikörper
  • AW212747 Antikörper
  • cide-a Antikörper
  • CIDEA Antikörper
  • MGC89985 Antikörper

Bezeichner auf Proteinebene für CIDEA

cell death activator CIDE-A , cell death-inducing DFFA-like effector A , cell death-inducing DFFA-like effector a , cell death-inducing DNA fragmentation factor, alpha subunit-like effector A

GENE ID SPEZIES
1149 Homo sapiens
12683 Mus musculus
468605 Pan troglodytes
490559 Canis lupus familiaris
527051 Bos taurus
768659 Gallus gallus
291541 Rattus norvegicus
703318 Macaca mulatta
493350 Xenopus (Silurana) tropicalis
495322 Xenopus laevis
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