Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) ELISA Kits

human homolog may play a role in regulation of transcription and splicing [RGD, Feb 2006].. Zusätzlich bieten wir Ihnen Cdc2-Related Kinase, Arginine/serine-Rich Antikörper (37) und Cdc2-Related Kinase, Arginine/serine-Rich Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
CRKRS 51755 Q9NYV4
CRKRS 69131 Q14AX6
CRKRS 192350 Q3MJK5
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Top Cdc2-Related Kinase, Arginine/serine-Rich ELISA Kits auf antikoerper-online.de

Showing 4 out of 8 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 34 pg/mL 78-5000 pg/mL   96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
$867.90
Details
Maus 78-5000 pg/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$1,029.60
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Ratte
0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$1,029.60
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Rind (Kuh)
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$1,029.60
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Weitere ELISA Kits für Cdc2-Related Kinase, Arginine/serine-Rich Interaktionspartner

Fruit Fly (Drosophila melanogaster) Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) Interaktionspartner

  1. Cdk12 suppresses genes that support metabolic functions in stressed conditions. Cdk12 is not a generally essential Pol II kinase and is not required for the transcription of essential and housekeeping genes at least in adult tissues.

  2. CDK12 plays a role in controlling the epigenetic transition between euchromatin and heterochromatin, suggesting a chromatin regulatory mechanism in neuronal behaviors.

  3. The phosphorylation of the C-terminal domain of the RNA polymerase II by Cdk12 provides an elegant mechanism in regulating timed splicing of newly synthesized mRNA molecules.

Human Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) Interaktionspartner

  1. CDK12 gene amplification can contribute to the pathogenesis of breast cancer.

  2. BRCA1 downregulation combined with CHK1 (zeige CHEK1 ELISA Kits) inhibition induced excessive amounts of DNA damage, resulting in an inability to complete the S-phase. Therefore, we suggest CHK1 (zeige CHEK1 ELISA Kits) inhibition as a strategy for targeting BRCA1- or CDK12-deficient tumors.

  3. In Ovarian Cancer patients CDK12 loss is consistently associated with a particular genomic instability pattern characterized by hundreds of tandem duplications

  4. Structures of CDK12/CycK (zeige CCNK ELISA Kits) complexes solved in the presence of AMP (zeige APRT ELISA Kits)-PNP (zeige NP ELISA Kits).

  5. Data show that most mutations prevent formation of the cyclin-dependent kinase 12 (Cdk12)/cyclin K (CycK (zeige CCNK ELISA Kits)) complex, rendering the kinase inactive.

  6. CDK12 affects RNA processing events in two distinct ways: Indirectly through generating factor-binding phospho-epitopes on the CTD of elongating RNAPII and directly through binding to specific factors

  7. CDK12 and CDK13 (zeige CDK13 ELISA Kits) losses in HCT116 cells preferentially affect expression of DNA damage response.

  8. CDK12 plays an important role in cotranscriptional processing of c-FOS transcripts

  9. CDK12 has properties that should confirm interest in its use as a biomarker.

  10. many CDK12 mutations are an unrecognized cause of HR defects in ovarian cancers

Mouse (Murine) Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) Interaktionspartner

  1. Report on the functions of Cdk12 during neural development in vivo, proposes a dual role for Cdk12 in neurogenesis and late stage neuronal migration via 2 distinct pathways

  2. The findings of this study suggest that Cdk12 and Cdk13 (zeige CDK13 ELISA Kits) regulate axonal elongation through a common signaling pathway that modulates Cdk5 (zeige CDK5 ELISA Kits) expression.

Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) Antigen-Profil

Beschreibung des Gens

human homolog may play a role in regulation of transcription and splicing

Genbezeichner und Symbole assoziert mit CRKRS

  • Cyclin-dependent kinase 12 (Cdk12) Antikörper
  • cyclin dependent kinase 12 (CDK12) Antikörper
  • cyclin-dependent kinase 12 (Cdk12) Antikörper
  • 1810022J16Rik Antikörper
  • AC017581 Antikörper
  • AI646528 Antikörper
  • anon-WO0140519.165 Antikörper
  • cg7597 Antikörper
  • Crk7 Antikörper
  • CRKR Antikörper
  • Crkrs Antikörper
  • D11Ertd752e Antikörper
  • dCDK12 Antikörper
  • Dmel\\CG7597 Antikörper
  • gi24668141 Antikörper
  • hCDK12 Antikörper
  • Pksc Antikörper

Bezeichner auf Proteinebene für CRKRS

CG7597-PA , CG7597-PB , CG7597-PC , Cdk12-PA , Cdk12-PB , Cdk12-PC , Cdc2-related kinase, arginine/serine-rich , CDC2-related protein kinase 7 , cell division cycle 2-related protein kinase 7 , cell division protein kinase 12 , CDC2-related kinase 7 , CDC2-related kinase, arginine/serine-rich , protein kinase for splicing component , cyclin-dependent kinase 12 isoform , cyclin-dependent kinase 12 , Cell division protein kinase 12

GENE ID SPEZIES
40385 Drosophila melanogaster
100354313 Oryctolagus cuniculus
51755 Homo sapiens
69131 Mus musculus
192350 Rattus norvegicus
511513 Bos taurus
100467815 Ailuropoda melanoleuca
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