Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 1 Proteine (CITED1)

CITED1 encodes a member of the CREB-binding protein/p300-interacting transactivator with Asp/Glu-rich C-terminal domain (CITED) family of proteins. Zusätzlich bieten wir Ihnen CITED1 Antikörper (60) und CITED1 Kits (12) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CITED1 4435 Q99966
CITED1 12705 P97769
Ratte CITED1 CITED1 64466  
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Showing 5 out of 8 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,442.50
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,442.50
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$785.40
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,469.50
Details

CITED1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 1 (CITED1) Interaktionspartnern

Mouse (Murine) Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 1 (CITED1) Interaktionspartner

  1. Dicer (zeige DICER1 Proteine) ablation in the early metanephric mesenchyme results in severe renal dysgenesis despite normal initial specification of nephron progenitors and ureteric bud outgrowth.

  2. The data indicated that serine phosphorylation at position 79 in the 63-84 domain is associated with PKC activation, and is required for both CITED1 nuclear translocation induced by PTH (zeige PTH Proteine)

  3. Loss of placental Cited1 leads to intrauterine organ growth restriction with decreased IGF-I (zeige IGF1 Proteine) and IGF-II expression and in IR and Igf1r (zeige IGF1R Proteine) signaling.

  4. CBP (zeige CREBBP Proteine) inactivation in mouse thymocytes leads to lymphoma

  5. role for CITED1 in the modulation of transcriptional events mediated by steroid hormone and cytokine signaling pathways

  6. The expression pattern of Cited2 (zeige CITED2 Proteine) overlaps that of Cited1, but its deletion, either alone or in combination with Cited1, does not disrupt epithelial differentiation of the metanephric mesenchyme.

  7. These observations suggest that, in addition to an increased gene copy number and upregulation of EGR2 (zeige EGR2 Proteine) and CITED1, an elevated erbB2 (zeige ERBB2 Proteine) transcript level involves the loss of 14-3-3sigma, which sequesters a key transcriptional regulator of the erbB2 (zeige ERBB2 Proteine) promoter.

  8. CITED1 negatively regulates osteoblastic differentiation in vitro and inhibits the cAMP-dependent stimulation of differentiation by intermittent PTH (zeige PTH Proteine).

  9. Renal medullary dysplasia in Cited1 mutant mice is a direct consequence of decreased tissue oxygenation resulting from placental insufficiency.

Human Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 1 (CITED1) Interaktionspartner

  1. Forced nuclear enrichment of CITED1 in a human WT cell line appears to enhance tumorigenicity, whereas ectopic cytosolic expression confers stem-like properties and an embryonic phenotype.

  2. Thus deficiency of Cited1 leads to hyper-activation of Wnt (zeige WNT2 Proteine) signaling and an exaggerated Wnt (zeige WNT2 Proteine) phenotype including elevated cell death

  3. The CITED1 expression is correlated with lymph node metastasis in patients with colorectal cancer.

  4. CITED1 expression remains active across all disease characteristics of Wilms tumor. It is found in the nucleus & cytosol. It is not found in normal kidney.

  5. epigenetic regulation is involved in the overexpression of CITED1 in papillary thyroid cancer

  6. TOX3 (zeige TOX3 Proteine) induces transcription in neuron depending on the presence of CITED1 or phosphorylated CREB (zeige CREB1 Proteine) in the transcriptionally active complex.

  7. CITED1 functions as a cell cycle-dependent transcriptional cofactor whose activity is regulated by phosphorylation

  8. CITED1 could play a role in Wilms' tumor initiation and pathogenesis.

CITED1 Protein Überblick

Protein Überblick

This gene encodes a member of the CREB-binding protein/p300-interacting transactivator with Asp/Glu-rich C-terminal domain (CITED) family of proteins. The encoded protein, also known as melanocyte-specific gene 1, may function as a transcriptional coactivator and may play a role in pigmentation of melanocytes. Alternatively spliced transcript variants have been described.

Genbezeichner und Symbole assoziert mit CITED1

  • Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 (cited1)
  • Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 (CITED1)
  • similar to Cbp/p300-interacting transactivator 1 (Melanocyte-specific protein 1) (CITED1)
  • Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 (Cited1)
  • Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 (Cited1)
  • AI316840 Protein
  • AU019144 Protein
  • CITED1 Protein
  • fi05d05 Protein
  • Msg1 Protein

Bezeichner auf Proteinebene für CITED1

Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 , cbp/p300-interacting transactivator 1 , Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 , similar to Cbp/p300-interacting transactivator 1 (Melanocyte-specific protein 1) , melanocyte-specific gene 1 , melanocyte-specific protein 1 , transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 , melanocyte-specific gene 1 protein

GENE ID SPEZIES
793303 Danio rerio
654297 Sus scrofa
465711 Pan troglodytes
703041 Macaca mulatta
4435 Homo sapiens
282182 Bos taurus
12705 Mus musculus
64466 Rattus norvegicus
100855937 Canis lupus familiaris
100356232 Oryctolagus cuniculus
100722170 Cavia porcellus
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