Cation Channel, Sperm Associated 1 Proteine (CATSPER1)

Calcium ions play a primary role in the regulation of sperm motility. Zusätzlich bieten wir Ihnen CATSPER1 Antikörper (27) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CATSPER1 117144 Q8NEC5
CATSPER1 225865 Q91ZR5
Ratte CATSPER1 CATSPER1 689349  
Direkt bei antikoerper-online bestellen
  • +49 (0)241 95 163 153
  • +49 (0)241 95 163 155
  • Online bestellen
  • orders@antikoerper-online.de

Top CATSPER1 Proteine auf antikoerper-online.de

Showing 5 out of 8 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 56 bis 61 Tage
5.753,97 €
Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 56 bis 61 Tage
8.202,81 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details

CATSPER1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine) ,
,

Weitere Proteine zu Cation Channel, Sperm Associated 1 (CATSPER1) Interaktionspartnern

Horse (Equine) Cation Channel, Sperm Associated 1 (CATSPER1) Interaktionspartner

  1. The CatSper channel is present in equine sperm but that the relationship of hyperactivated motility to calcium influx is weak.

Human Cation Channel, Sperm Associated 1 (CATSPER1) Interaktionspartner

  1. Electrophysiological studies showed a significant increase in Cd(2 (zeige CD2 Proteine)+) and manganese (Mn(2+)) currents through the CaV3.1 (zeige CACNA1G Proteine) mutants as well as a reduction in the inhibitory effect of Cd(2 (zeige CD2 Proteine)+) on the Ca(2 (zeige CA2 Proteine)+) current.

  2. Sperm with a near absence of CatSper current failed to respond to activation of CatSper by progesterone and there was fertilization failure at IVF (zeige SCN5A Proteine).

  3. The role of CATSPER1 in idiopathic asthenospermia pathogenesis: exonal SNP rs1893316 in CATSPER1 significantly correlated with idiopathic asthenospermia risk

  4. Sox5 (zeige SOX5 Proteine) and Sox9 (zeige SOX9 Proteine) cause a significant increase in transactivation of the Catsper1 promoter.

  5. Progesterone via CatSper activates the PI3K (zeige PIK3CA Proteine)-AKT (zeige AKT1 Proteine) pathway required for motility and hyperactivation but not for acrosome reaction.

  6. This work reports the cloning and characterization of the promoter regions in the human and murine Catsper1 genes. The immediate upstream region and the first exon in the human CATSPER1 gene negatively regulate transcriptional activity. The mouse Catsper1 promoter exhibited transcriptional activity in both orientations and displayed significant expression levels in mouse testis in vivo.

  7. CatSper is indeed the principal Ca2 (zeige CA2 Proteine)+ channel of human spermatozoa, and that it is strongly potentiated by progesterone.

  8. CatSper activation can elicit functionally different behaviors according to the sensitivity of the Ca(2 (zeige CA2 Proteine)+) store, which may be regulated by capacitation and NO from the cumulus.

  9. It was shown that odorants directly activate CatSper without involving G protein-coupled receptors and cAMP. Membrane-permeable analogues of cyclic nucleotides activated CatSper directly via an extracellular site.

  10. The decreased or abnormal expression of the CatSper1 protein may be a factor involved in the pathogenesis of idiopathic asthenozoospermia.

Mouse (Murine) Cation Channel, Sperm Associated 1 (CATSPER1) Interaktionspartner

  1. patch clamping of sperm revealed that CRISP1 (zeige CRISP1 Proteine) has the ability to regulate CatSper, the principal sperm Ca(2 (zeige CA2 Proteine)+) channel involved in hyperactivation and essential for fertility

  2. Catsper transports the Ca(2 (zeige CA2 Proteine)+) involved in the regulation of cAMP-dependent and tyrosine phosphorylation pathways required for sperm capacitation.

  3. These results establish a critical role of LRRC52 in KSPER channels and demonstrate that loss of a non-pore-forming auxiliary subunit results in severe fertility impairment.

  4. SLO3 (zeige KCNU1 Proteine) K+ channels have a role in controlling calcium entry through CATSPER channels in sperm

  5. Using mice lacking both SLO3 (zeige KCNU1 Proteine) and CATSPER1 subunits, the results show conclusively that the voltage-activated outward current present in Slo3 (zeige KCNU1 Proteine) (-/-) sperm is abolished when CATSPER is also deleted.

  6. The mouse Catsper1 promoter exhibited transcriptional activity in both orientations and displayed significant expression levels in the mouse testis in vivo.

  7. Immunization with B-cell epitopes in transmembrane domains and pore region of CatSper1 can cause significant antifertility effects in male mice.

  8. Yijingfang can increase the sperm count and the expression of CatSper1.

  9. KSper/Slo3 (zeige KCNU1 Proteine) is the primary spermatozoan K(+) channel (zeige KCNC4 Proteine),and KSper may play a critical role in acquisition of normal morphology and sperm motility when faced with hyperosmotic challenges.

  10. The initial phase of the increases in intracellular calcium concentration induced by BSA requires the CATSPER channel, but not the voltage-gated calcium channel.

CATSPER1 Protein Überblick

Protein Überblick

Calcium ions play a primary role in the regulation of sperm motility. This gene belongs to a family of putative cation channels that are specific to spermatozoa and localize to the flagellum. The protein family features a single repeat with six membrane-spanning segments and a predicted calcium-selective pore region.

Genbezeichner und Symbole assoziert mit CATSPER1

  • cation channel, sperm associated 1 (CATSPER1)
  • cation channel, sperm associated 1 (Catsper1)
  • Catsper Protein
  • KSper Protein
  • SPGF7 Protein

Bezeichner auf Proteinebene für CATSPER1

cation channel, sperm associated 1 , cation channel sperm-associated protein 1 , hCatSper , sperm ion channel , sperm-associated cation channel 1 , cation channel of sperm 1 , sperm protein CATSPER1

GENE ID SPEZIES
476016 Canis lupus familiaris
523556 Bos taurus
721869 Macaca mulatta
100058005 Equus caballus
100392349 Callithrix jacchus
100448226 Pongo abelii
100595887 Nomascus leucogenys
117144 Homo sapiens
225865 Mus musculus
689349 Rattus norvegicus
Ausgewählte Anbieter für CATSPER1 Proteine (CATSPER1)
Haben Sie etwas anderes gesucht?