anti-Cathepsin C (CTSC) Antikörper

The protein encoded by CTSC, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. Zusätzlich bieten wir Ihnen Cathepsin C Kits (32) und Cathepsin C Proteine (19) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CTSC 1075 P53634
CTSC 13032 P97821
CTSC 25423 P80067
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Top anti-Cathepsin C Antikörper auf antikoerper-online.de

Showing 10 out of 87 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-CTSC Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: PANC1 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from Jurkat cells, treated with etoposide 25uM 1h, using Dipeptidyl-peptidase 1 (heavy chain,Cleaved-Arg394) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 16 Days
$175.80
Details
Rind (Kuh) Kaninchen Biotin DB, EIA, ID, IF, IP, RIA, WB   1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$434.50
Details
Human Ziege Unkonjugiert IHC (p), ELISA Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cells, using CTSC antibody. Immunohistochemistry of paraffin-embedded human stomach using CTSC antibody at dilution of 1:100 (x40 lens). 100 μL Anmelden zum Anzeigen 16 Days
$323.13
Details
Human Maus Unkonjugiert IHC (p), ELISA, WB Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Anmelden zum Anzeigen 7 bis 9 Tage
$595.83
Details
Human Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$350.00
Details

CTSC Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Weitere Antikörper gegen Cathepsin C Interaktionspartner

Human Cathepsin C (CTSC) Interaktionspartner

  1. CTSC gene missense mutation is responsible for Papillo- Lefevre syndrome in a Turkish family.

  2. analysis of fluorescent substrates provides a detailed S' specificity study of cathepsin C

  3. Mutation screening of the CTSC gene from the two patients revealed the presence of the same homozygous nonsense mutation in Papillon-Lefevre syndrome and Haim-Munk syndromes. Phenotypic variants of the same rare disease caused by mutations of the cathepsin C (CTSC) gene.

  4. Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases.

  5. CTSC was associated with albuminuria in type 2 diabetes patients.

  6. Homozygous mutation 901G>A in exon 7 of CTSC gene is associated with Papillon-Lefevre syndrome.

  7. Results identify a missense mutation in CTSC gene that segregate within a family with Papillon-Lefevre syndrome.

  8. Papillon-Lefevre syndrome cause by homozygous nonsense mutation of cathepsin C gene.

  9. CatC has a role in the selective tuning of innate and adaptive immune responses, relevant to a chronic immune disease, such as atherosclerosis.

  10. cathepsin C in GCF (zeige GUCY2F Antikörper) does not seem to have an effect on the pathogenesis of periodontal diseases.

Mouse (Murine) Cathepsin C (CTSC) Interaktionspartner

  1. During the active remyelinating phase, both CysF knockdown (CysFKD) and microglial-selective CatC overexpression (CatCOE) showed a worsening of the demyelination in Plp (zeige C3 Antikörper)(4e/-) transgenic mice. Conversely, during the chronic demyelinating phase, CatC knockdown (CatCKD) ameliorated the demyelination. Our results suggest that the balance between CatC and CysF expression controls the demyelination and remyelination process.

  2. Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases.

  3. Double immunofluorescence analysis showed that CTLA-2alpha was co-localized with cathepsin L (zeige CTSL1 Antikörper), cathepsin C, and TINAGL1 (zeige TINAGL1 Antikörper) in placenta.

  4. CatC has a role in the selective tuning of innate and adaptive immune responses, relevant to a chronic immune disease, such as atherosclerosis.

  5. Data indicate that all-trans retinoic acid (ATRA), which induces miR (zeige MLXIP Antikörper)-23a expression, decreases cathepsin C (CTSC) expression and granzyme B (zeige Gzmb Antikörper) activity leading to impaired NK cell cytotoxicity.

  6. These results establish that DPPI is a major determinant of survival following Klebsiella pneumoniae lung infection and suggest that the survival disadvantage in DPPI(+/+) mice is in part due to processing of surfactant protein D (zeige SFTPD Antikörper) by DPPI.

  7. found no significant role for CtsC during mammary carcinogenesis but revealed squamous carcinogenesis to be functionally dependent on CtsC

  8. Late stage cathepsin C, CXCL13 (zeige CXCL13 Antikörper) and Ki-67 (zeige MKI67 Antikörper) overexpression correlate with regional neuropathology in a bovine spongiform encephalopathy transgenic murine model.

  9. Proinflammatory cytokines induce expression and release of cathepsin C in microglial cells during neuroinflammatory progression.

  10. The production of IL-1beta (zeige IL1B Antikörper) by macrophages, neutrophils, and mast cells in vitro is dependent on caspase-1 (zeige CASP1 Antikörper) but not on cathepsin C.

Cathepsin C (CTSC) Antigen-Profil

Protein Überblick

The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit anti-Cathepsin C (CTSC) Antikörper

  • cathepsin C L homeolog (ctsc.L) Antikörper
  • cathepsin C (ctsc) Antikörper
  • cathepsin C (CTSC) Antikörper
  • cathepsin C (TP03_0357) Antikörper
  • cathepsin C (CMU_003360) Antikörper
  • cathepsin CPC1 (CPC1) Antikörper
  • cathepsin C (NAEGRDRAFT_80477) Antikörper
  • cathepsin C (NAEGRDRAFT_37577) Antikörper
  • cathepsin C (Ctsc) Antikörper
  • cathepsin C (Smp_183330) Antikörper
  • cathepsin J (Ctsj) Antikörper
  • AI047818 Antikörper
  • CATC Antikörper
  • CATP Antikörper
  • CatRLP Antikörper
  • CPPI Antikörper
  • Ctsp Antikörper
  • DPP-I Antikörper
  • DPP1 Antikörper
  • DPPI Antikörper
  • HMS Antikörper
  • JP Antikörper
  • JPD Antikörper
  • MGC69126 Antikörper
  • MGC107782 Antikörper
  • PALS Antikörper
  • PDON1 Antikörper
  • PLS Antikörper

Bezeichner auf Proteinebene für anti-Cathepsin C (CTSC) Antikörper

cathepsin C , dipeptidyl peptidase 1 , dipeptidyl peptidase 1 isoform a preproprotein , DPPI , DPP-I , cathepsin J , Dipeptidyl-peptidase 1 , dipeptidyl peptidase I , dipeptidyl transferase , dipeptidyl-peptidase I , dipeptidyl-peptidase 1 , dipeptidylpeptidase 1 , Cat P , cathepsin L-related protein , cathepsin P , catlrp-p , gene/Cathepsin L-related protein

GENE ID SPEZIES
380203 Xenopus laevis
407938 Xenopus (Silurana) tropicalis
451469 Pan troglodytes
705320 Macaca mulatta
3500364 Theileria parva strain Muguga
6997925 Cryptosporidium muris RN66
7899372 Toxoplasma gondii ME49
8851692 Naegleria gruberi strain NEG-M
8855504 Naegleria gruberi strain NEG-M
100172530 Pongo abelii
352958 Bos taurus
1075 Homo sapiens
13032 Mus musculus
25423 Rattus norvegicus
100101594 Oryctolagus cuniculus
100714387 Cavia porcellus
403458 Canis lupus familiaris
419014 Gallus gallus
101112686 Ovis aries
8346758 Schistosoma mansoni
26898 Mus musculus
29174 Rattus norvegicus
Ausgewählte Anbieter für anti-Cathepsin C (CTSC) Antikörper
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