anti-Cartilage Oligomeric Matrix Protein (COMP) Antikörper

The protein encoded by COMP is a noncollagenous extracellular matrix (ECM) protein. Zusätzlich bieten wir Ihnen COMP Kits (70) und COMP Proteine (21) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
COMP 25304 P35444
COMP 1311 P49747
COMP 12845 Q9R0G6
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Top anti-COMP Antikörper auf antikoerper-online.de

Showing 10 out of 124 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Ratte Unkonjugiert EIA, IHC (fro), IHC (p), IP, WB   2 mL Anmelden zum Anzeigen 6 bis 8 Tage
$467.50
Details
Ratte Huhn Unkonjugiert WB 0.1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$544.50
Details
Human Kaninchen Unkonjugiert WB Raji cell lysates probed with Rabbit Anti-COMP Polyclonal Antibody, Unconjugated (ABIN2559644) at 1:300 in 4˚C. Followed by conjugation to secondary antibody at 1:5000 for 90min at 37˚C. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$306.90
Details
Human Kaninchen Unkonjugiert WB   0.1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$731.50
Details
Rind (Kuh) Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of COMP Antibody (Center) (ABIN390893) in Jurkat cell line lysates (35 µg/lane). COMP (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with COMP Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus Unkonjugiert WB Western Blot analysis of COMP expression in transfected 293T cell line by COMP MaxPab polyclonal antibody.<br><br>Lane 1: COMP transfected lysate(79.64 KDa).<br>Lane 2: Non-transfected lysate.<br> 50 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Kaninchen HRP WB   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Ratte Unkonjugiert IHC (fro), IHC (p), IP, IHC, ELISA, WB Western Blot: COMP/Thrombospondin-5 Antibody (MA37C94 (HC484D1)) [ABIN2557989] - Purifed COMP from conditioned media. Image from verified customer review. 1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$444.19
Details

COMP Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-COMP Antikörper

  1. Human Polyclonal COMP Primary Antibody für WB - ABIN947722 : Clement, Aphkhazava, Nieves, Callaway, Olszewski, Rotzschke, Santambrogio: Protein expression profiles of human lymph and plasma mapped by 2D-DIGE and 1D SDS-PAGE coupled with nanoLC-ESI-MS/MS bottom-up proteomics. in Journal of proteomics 2013 (PubMed)

Weitere Antikörper gegen COMP Interaktionspartner

Horse (Equine) Cartilage Oligomeric Matrix Protein (COMP) Interaktionspartner

  1. The aims of this study were to investigate the proteomic composition of injured tendons during early and late disease stages to identify disease-specific cleavage patterns of the extracellular matrix protein cartilage oligomeric matrix protein (COMP).

  2. The present results suggest that not only type III collagen (zeige COL3A1 Antikörper) but also cartilage oligomeric matrix protein is involved in the repair and remodeling processes of the digital flexor tendon.

  3. Within the limitations of the study design, production of COMP during healing of skin wounds does not appear to be influenced by wound type or anatomic site, nor does it appear to be correlated with TGF-beta1 (zeige TGFB1 Antikörper) concentrations.

  4. COMP concentrations in digital flexor tendon sheath synovial fluid were significantly greater than those in normal horses with noninfected tenosynovitis caused by intrathecal tendon/ligament tearing, but not by other lesions.

  5. The present study indicates that dynamic in vivo compression at high load and frequency lowers matrix content of COMP in the articular cartilage of the third carpal bone.

Human Cartilage Oligomeric Matrix Protein (COMP) Interaktionspartner

  1. Data show that a rare missense variant in the COMP gene (cartilage oligomeric matrix protein) and a frameshift variant in the CHADL gene (chondroadherin-like protein) strongly associate with osteoarthritis total hip replacement.

  2. COMP is a novel biomarker in breast cancer, which contributes to the severity of the disease by metabolic switching and increasing invasiveness and tumor cell viability, leading to reduced survival in animal models and human patients.

  3. The average sCOMP level was highest among the controls and lowest among the infected children. In the juvenile idiopathic arthritis patients, the level of sCOMP was not associated with the level of CRP (zeige CRP Antikörper) or with clinical signs of disease activity.

  4. COMT (zeige COMT Antikörper) Val158Met polymorphism may influence responses to dextromethorphan (30 mg/d) by decreasing depressive symptoms in BD patients.

  5. The serum COMP level has the potential to be used as a biological marker for differentiating between patients with rheumatoid arthritis and healthy individuals.

  6. The current study expanded the mutation spectrum of the COMP gene, and contributes to the understanding of phenotype/genotype of COMPassociated diseases.

  7. In the absence of ultrasonographic knee cartilage deformation, the response of serum lubricin (zeige PRG4 Antikörper) and COMP following acute vigorous exercise indicates an increase in joint lubrication and cartilage metabolism, respectively, which appears largely independent of exercise modality.

  8. Running appears to decrease knee intra-articular pro-inflammatory cytokine concentration and facilitates the movement of COMP from the joint space to the serum.

  9. Results suggest that serum oligomeric matrix protein and hyaluronic acid (COMP and HA) concentrations can be used to predict early cartilage lesions in the knee.

  10. Serum COMP levels are predictive of subsequent structural changes and incidence of painful knee osteoarthritis.

Mouse (Murine) Cartilage Oligomeric Matrix Protein (COMP) Interaktionspartner

  1. COMP could normally have a protective role against PASMC phenotype switching

  2. these findings revealed the essential role of COMP in retarding the development of vascular aging and vascular smooth muscle cell senescence.

  3. COMP deficiency drove macrophages toward the atherogenic phenotype and thereby aggravated atherosclerotic calcification.

  4. COMP forms a complex with collagens intracellularly that is a prerequisite for collagen secretion.

  5. COMP-Ang1 (zeige ANGPT1 Antikörper) can enhance BMP2 (zeige BMP2 Antikörper)-induced cranial bone regeneration with increased pericyte recruitment. Combined delivery of the proteins might be a therapeutic strategy to repair cranial bone damage.

  6. COMP deficiency shortened tail-bleeding and clotting time and accelerated ferric-chloride-induced thrombosis. COMP specifically inhibited thrombin-induced platelet aggregation, activation, and retraction and the thrombin-mediated cleavage of fibrinogen.

  7. COMP immunoreactivity was observed in about half of the investigated plaques from the ApoE (zeige APOE Antikörper) null mice, mainly located along the intima-medial border. Plaques in the brachiocephalic artery from ApoE (zeige APOE Antikörper) mice lacking COMP were increased in size with 54%.

  8. study will facilitate better awareness of the differential diagnoses that might be associated with the PSACH/MED spectrum and subsequent care of PSACH/MED patients

  9. The lack of arthritis, together with high levels of COMP-specific antibodies, in COMP-deficient mice indicates that susceptibility to arthritis is COMP specific and that endogenous expression of COMP in wild-type mice tolerizes B cells in vivo.

  10. results imply that COMP is not a key upstream mediator of the anabolic effects of ML on the skeleton.

Cow (Bovine) Cartilage Oligomeric Matrix Protein (COMP) Interaktionspartner

  1. COMP synthesis is differentially regulated by TGFbeta1 (zeige TGFB1 Antikörper) in the surface and middle zones of bovine articular cartilage.

  2. role for proteinases other than MMPs in the degradation of COMP in cartilage

  3. COMP mutant expression in tendon fibroblasts leads to increased apoptotic cell death irrespective of the secretory characteristics of mutant COMP

  4. COMP mRNA expression level was markedly increased by ball oscillation.

  5. COMP acts as a catalyst in collagen fibrillogenesis.

COMP Antigen-Profil

Protein Überblick

The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).

Genbezeichner und Symbole assoziert mit COMP

  • cartilage oligomeric matrix protein (COMP) Antikörper
  • cartilage oligomeric matrix protein (sce3551) Antikörper
  • cartilage oligomeric matrix protein (CJA_1292) Antikörper
  • cartilage oligomeric matrix protein (Comp) Antikörper
  • COMP Antikörper
  • EDM1 Antikörper
  • EPD1 Antikörper
  • MED Antikörper
  • PSACH Antikörper
  • THBS5 Antikörper
  • TSP5 Antikörper

Bezeichner auf Proteinebene für COMP

cartilage oligomeric matrix protein , TSP5 , cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple) , cartilage oligomeric matrix protein(pseudoachondroplasia, epiphyseal dysplasia 1, multiple) , pseudoachondroplasia (epiphyseal dysplasia 1, multiple) , thrombospondin-5 , putative cartilage oligomeric matrix protein

GENE ID SPEZIES
469068 Pan troglodytes
5808591 Sorangium cellulosum So ce56
6415089 Cellvibrio japonicus Ueda107
100033911 Equus caballus
25304 Rattus norvegicus
1311 Homo sapiens
12845 Mus musculus
281088 Bos taurus
100720040 Cavia porcellus
396554 Sus scrofa
476665 Canis lupus familiaris
420120 Gallus gallus
101107864 Ovis aries
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