anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) Antikörper

Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. Zusätzlich bieten wir Ihnen Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase Proteine (7) und Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CILP 8483 O75339
CILP 214425 Q66K08
CILP 315761  
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Top anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase Antikörper auf antikoerper-online.de

Showing 10 out of 45 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Ratte Ziege Unkonjugiert ELISA, WB ABIN185679 (0.03µg/ml) staining of rat spinal cord lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Ratte Ziege Unkonjugiert IHC (p), ELISA, WB ABIN251581(0.03ug/ml) staining of Rat Spinal Cord lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Immunohistochemistry-Paraffin: CILP-1 Antibody [ABIN2515816] - CILP using ABIN2515816 in Rat Spinal Cord lysate (35ug protein in RIPA buffer) at 0.03ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Hund Ziege Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$455.40
Details
Human Kaninchen Unkonjugiert WB MCF-7 lysate probed with Rabbit Anti-CILP Polyclonal Antibody, Unconjugated  at 1:5000 for 90min at 37˚C. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$306.90
Details
Maus Kaninchen Unkonjugiert ICC, IHC, IP, WB Used in DAB staining on fromalin fixed paraffin-embedded Brain tissue 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$360.00
Details
Human Kaninchen HRP WB   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Maus Unkonjugiert ELISA Detection limit for recombinant GST tagged CILP is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Ratte Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details

CILP Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Rat (Rattus)
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Am meisten referenzierte anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase Antikörper

  1. Rat (Rattus) Polyclonal CILP Primary Antibody für IHC (p), ELISA - ABIN251581 : Seki, Kawaguchi, Chiba, Mikami, Kizawa, Oya, Mio, Mori, Miyamoto, Masuda, Tsunoda, Kamata, Kubo, Toyama, Kimura, Nakamura, Ikegawa: A functional SNP in CILP, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease. in Nature genetics 2005 (PubMed)

Weitere Antikörper gegen Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase Interaktionspartner

Human Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) Interaktionspartner

  1. Meta-analysis. Our results confirm the positive association between CILP and intervertebral disc degeneration, providing novel clues for clarifying the role of CILP in the development of IVD (zeige IVD Antikörper).

  2. CILP is involved in the etiology of intervertebral disc degeneration among young adults.

  3. The researchers found that the single nucleotide polymorphism (1184T/C) of the CILP gene is associated an increased risk of lumbar disc degeneration in male athletes.

  4. CILP regulates TGF-beta (zeige TGFB1 Antikörper) signaling and that this regulation has a crucial role in the etiology and pathogenesis of LDD.

  5. These observations, together with the finding that CILP protein binds and inhibits TGF-beta1 (zeige TGFB1 Antikörper), suggest that CILP and TGF-beta1 (zeige TGFB1 Antikörper) may form a functional feedback loop that controls chondrocyte metabolism.

  6. SNP analysis suggested that the CILP gene is not a major risk factor for symptoms of lumbar disc disease in Finnish or Chinese populations.

  7. the CILP gene 1184T/C polymorphism is a significant risk factor for lumbar disc degeneration occurrence in Japanese collegiate judo athletes

Mouse (Murine) Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) Interaktionspartner

  1. Overexpression of CILP in the nucleus pulposus cells promotes disc degeneration, indicating that CILP plays a direct role in the pathogenesis of lumbar disc disease.

Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) Antigen-Profil

Protein Überblick

Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins\; an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease.

Genbezeichner und Symbole assoziert mit CILP

  • cartilage intermediate layer protein (CILP) Antikörper
  • cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (Cilp) Antikörper
  • cartilage intermediate layer protein (Cilp) Antikörper
  • caseinolytic mitochondrial matrix peptidase chaperone subunit (CLPX) Antikörper
  • cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (cilp) Antikörper
  • cartilage intermediate layer protein 1 (LOC100336614) Antikörper
  • 9830114D16 Antikörper
  • C130036G17Rik Antikörper
  • CILP Antikörper
  • CILP-1 Antikörper
  • HsT18872 Antikörper
  • im:7137994 Antikörper
  • NTPPH Antikörper

Bezeichner auf Proteinebene für CILP

cartilage intermediate layer protein 1 , cartilage intermediate layer protein 1 C1 , cartilage intermediate layer protein 1 C2 , cartilage intermediate-layer protein , CILP-1 , nucleotide pyrophosphohydrolase , cartilage intermediate layer protein, nucleotide pyrophosphohydrolase , ClpX caseinolytic protease X homolog , cartilage intermediate layer protein 1-like , CILP protein

GENE ID SPEZIES
8483 Homo sapiens
214425 Mus musculus
315761 Rattus norvegicus
397672 Sus scrofa
415533 Gallus gallus
453514 Pan troglodytes
487603 Canis lupus familiaris
100138870 Bos taurus
100224477 Taeniopygia guttata
100390902 Callithrix jacchus
100475451 Ailuropoda melanoleuca
100541878 Meleagris gallopavo
100586830 Nomascus leucogenys
553329 Danio rerio
100336614 Bos taurus
100053337 Equus caballus
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