anti-Carbonyl Reductase 1 (CBR1) Antikörper

Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. Zusätzlich bieten wir Ihnen CBR1 Proteine (22) und CBR1 Kits (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CBR1 873 P16152
CBR1 12408 P48758
CBR1 29224 P47727
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Top anti-CBR1 Antikörper auf antikoerper-online.de

Showing 10 out of 119 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-CBR1 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>OVCAR-3 cell lysate WB Suggested Anti-CBR1 <br /> Antibody Titration: 0.2-1 µg/mL <br /> Positive Control: OVCAR-3 cell lysate <br /> CBR1 is supported by BioGPS gene expression data to be expressed in OVCAR3 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-CBR1 Antibody Titration: </b>1.25ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Ziege Unkonjugiert IHC, ELISA, WB ABIN184784 (3 µg/mL) staining of paraffin embedded Human Kidney. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining. ABIN184784 staining (0.2 µg/mL) of Human Liver lysate (RIPA buffer, 30 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from HeLa cells, using CBR1 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using CBR1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Ziege Unkonjugiert IHC (p), WB   0.1 mg Anmelden zum Anzeigen 10 bis 12 Tage
$411.13
Details
Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged CBR1 is approximately 1ng/ml as a capture antibody. Western Blot detection against Immunogen (56.21 KDa) . 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Human Kaninchen Unkonjugiert IC, IF, IHC, WB Immunofluorescent analysis of CBR1 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of CBR1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Ziege Unkonjugiert IHC (p), ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details

CBR1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Rat (Rattus)


Am meisten referenzierte anti-CBR1 Antikörper

  1. Cow (Bovine) Polyclonal CBR1 Primary Antibody für IHC, WB - ABIN2782364 : Lim, Shin, Jo, Jyothi, Nguyen, Choi, Kim, Park, Eun, Yoon, Ha, Kim: Carbonyl reductase 1 is an essential regulator of skeletal muscle differentiation and regeneration. in The international journal of biochemistry & cell biology 2013 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal CBR1 Primary Antibody für ELISA, WB - ABIN560201 : Bains, Karkling, Grigliatti, Reid, Riggs: Two nonsynonymous single nucleotide polymorphisms of human carbonyl reductase 1 demonstrate reduced in vitro metabolism of daunorubicin and doxorubicin. in Drug metabolism and disposition: the biological fate of chemicals 2009 (PubMed)
    Show all 2 Pubmed References

  3. Cow (Bovine) Polyclonal CBR1 Primary Antibody für WB - ABIN2782365 : Cheon, Shim, Kim, Hara, Lubec: Protein levels of genes encoded on chromosome 21 in fetal Down syndrome brain: Challenging the gene dosage effect hypothesis (Part IV). in Amino acids 2003 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal CBR1 Primary Antibody für ELISA, WB - ABIN560202 : Lakhman, Chen, Gonzalez-Covarrubias, Schuetz, Blanco: Functional characterization of the promoter of human carbonyl reductase 1 (CBR1). Role of XRE elements in mediating the induction of CBR1 by ligands of the aryl hydrocarbon receptor. in Molecular pharmacology 2007 (PubMed)

Weitere Antikörper gegen CBR1 Interaktionspartner

Human Carbonyl Reductase 1 (CBR1) Interaktionspartner

  1. The ability of human carbonyl reductase 1 to efficiently catalyze the reduction of glutathionylated aldehydes derived from lipid peroxidation, that in the case of glutathionylated-4-hydroxyalkanals is associated to the ability to oxidize the hemiacetal hydroxyl group

  2. Data suggest that fatty acids and acyl-CoAs bind competitively with respect to substrate binding to carbonyl reductase 1 (CBR1), an enzyme involved in first-pass drug metabolism in intestinal mucosa; inhibition of CBR1 by these products of digestion may lead to food-drug interactions.

  3. AKR1C3 (zeige AKR1C3 Antikörper) is the primary enzyme and CBR1 is a minor enzyme responsible for warfarin reduction in human liver cytosol.

  4. These results suggest that CR1 (zeige CR1 Antikörper) induces apoptosis by activating the caspase (zeige CASP3 Antikörper) pathway via binding to TNFR1 (zeige TNFRSF1A Antikörper).

  5. Critical insights into the substrate selectivity of hCBR1 and the interaction between hCBR1 and glutathione.

  6. Up-Regulation of Carbonyl Reductase 1 Renders Development of Doxorubicin Resistance in Human Gastrointestinal Cancers

  7. CBR1 decreases promoted tumor proliferation and growth as well as invasion and metastasis; CBR1 has potential to become a new candidate for molecular targeting therapy.

  8. Inhibition of CBR1 may increase the efficacy of daunorubicin in cancer tissue.

  9. Protein products of AKR1C1 (zeige DDH Antikörper), AKR1C2 (zeige AKR1C2 Antikörper), AKR7A3 (zeige AKR7A3 Antikörper), CYP3A4 (zeige CYP3A4 Antikörper), and carbonyl reductase (CBR1) were found in tumors and those of AKR1C1 (zeige DDH Antikörper), AKR7A3 (zeige AKR7A3 Antikörper), and CBR1 correlated with their transcript levels.

  10. we suggest that PEP-1-CBR1 protein may be a therapeutic agent for the treatment of ischemic injuries as well as oxidative-stress-induced (zeige SQSTM1 Antikörper) cell damage and death.

Pig (Porcine) Carbonyl Reductase 1 (CBR1) Interaktionspartner

  1. two Cys residues, Cys 149 and Cys 226, are involved in the enzyme activity; Cys 226 is involved in binding of the cofactor NADPH.

Cow (Bovine) Carbonyl Reductase 1 (CBR1) Interaktionspartner

  1. results indicate that the disturbances in 9-KPR activity in bovine retained placenta exist but their reasons still require further experiments

Mouse (Murine) Carbonyl Reductase 1 (CBR1) Interaktionspartner

  1. CBR1 plays a critical role in controlling redox balance and detoxifying lipid peroxidation during muscle differentiation and regeneration.

  2. CBR1 attenuates apoptosis and promotes cell survival in pancreatic beta-cell lines under glucotoxic and glucolipotoxic conditions via reducing ROS (zeige ROS1 Antikörper) generation

CBR1 Antigen-Profil

Protein Überblick

Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q.

Genbezeichner und Symbole assoziert mit CBR1

  • carbonyl reductase 1 (cbr1) Antikörper
  • carbonyl reductase 1 (CBR1) Antikörper
  • carbonyl reductase [NADPH] 1 (LOC100222525) Antikörper
  • carbonyl reductase 1 S homeolog (cbr1.S) Antikörper
  • carbonyl reductase (Smp_033530.3) Antikörper
  • carbonyl reductase [NADPH] 1 (LOC610164) Antikörper
  • carbonyl reductase 1 (Cbr1) Antikörper
  • 9-KPR Antikörper
  • AW261796 Antikörper
  • Cbr Antikörper
  • CR Antikörper
  • hCBR1 Antikörper
  • LOC100222525 Antikörper
  • MGC131152 Antikörper
  • SDR21C1 Antikörper

Bezeichner auf Proteinebene für CBR1

carbonyl reductase [NADPH] 1 , carbonyl reductase 1 , 15-hydroxyprostaglandin dehydrogenase , 20-beta-hydroxysteroid dehydrogenase , NADPH-dependent carbonyl reductase 1 , prostaglandin 9-ketoreductase , prostaglandin-E(2) 9-reductase , carbonyl reductase , carbonyl reductase (NADPH) 1 , short chain dehydrogenase/reductase family 21C, member 1 , 20-hydroxysteroid dehydrogenase , prostaglandin E(2) 9-keto reductase , NADPH:secondary-alcohol oxidoreductase , Carbonyl reductase [NADPH] 1 (NADPH-dependent carbonyl reductase 1) , Cbr 1

GENE ID SPEZIES
373866 Danio rerio
496612 Xenopus (Silurana) tropicalis
100172097 Pongo abelii
100222525 Taeniopygia guttata
734804 Xenopus laevis
8353921 Schistosoma mansoni
873 Homo sapiens
418512 Gallus gallus
610164 Canis lupus familiaris
397143 Sus scrofa
515946 Bos taurus
100009528 Oryctolagus cuniculus
12408 Mus musculus
29224 Rattus norvegicus
Ausgewählte Anbieter für anti-CBR1 (CBR1) Antikörper
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