Calpain 5 Proteine (CAPN5)

Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. Zusätzlich bieten wir Ihnen Calpain 5 Antikörper (48) und Calpain 5 Kits (8) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CAPN5 726 O15484
CAPN5 12337 O08688
CAPN5 171495 Q8R4C0
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Top Calpain 5 Proteine auf antikoerper-online.de

Showing 5 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
Details
HOST_Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 7 bis 8 Tage
235,20 €
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
3.670,16 €
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HOST_Escherichia coli (E. coli) Maus T7 tag,His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
588,57 €
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CAPN5 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine) ,
,
Rat (Rattus)

Weitere Proteine zu Calpain 5 (CAPN5) Interaktionspartnern

Human Calpain 5 (CAPN5) Interaktionspartner

  1. CAPN5 localization at the photoreceptor synapse and with mitochondria explains the neural circuitry phenotype in human CAPN5 disease alleles.

  2. A novel CAPN5 (c.750G>T, p.Lys250Asn) missense mutation causes uveitis and neovascular retinal detachment.

  3. CAPN5 mutation in hereditary uveitis: the R243L mutation increases calpain catalytic activity and triggers intraocular inflammation

  4. CAPN5 expression can be suppressed by shRNA-based RNA interference

  5. autosomal dominant neovascular inflammatory vitreoretinopathy is due to CAPN5 gain-of-function rather than haploinsufficiency.

  6. Calpain-5 mutations cause autoimmune uveitis, retinal neovascularization, and photoreceptor degeneration.

  7. Results describe the cloning and characterization of rat calpain-5, which is highly homologous to human and mouse sequences.

  8. CAPN5 polymorphisms are associated with a risk of polycystic ovary syndrome.

  9. CAPN5 seems to influence traits related to increased risk for cardiovascular diseases and play a role as a candidate gene for metabolic syndrome

  10. We have found significant interaction between CAPN5 and PPARD (zeige PPARD Proteine) genes that reduces risk for obesity in 55%. CAPN5 and PPARD (zeige PPARD Proteine) gene products may also interact in vivo.

Mouse (Murine) Calpain 5 (CAPN5) Interaktionspartner

  1. CAPN5 mutation in hereditary uveitis: the R243L mutation increases calpain catalytic activity and triggers intraocular inflammation

  2. CAPN5 is found in punctate domains associated with promyelocytic leukemia (PML (zeige PML Proteine)) protein within the nucleus.

  3. Despite the numerous expression sites of Capn5, the majority of Capn5-null mice were viable and fertile and appeared healthy

  4. calpain-derived Htt (zeige HTT Proteine) fragmentation has a role in Huntington's disease and aberrant activation of calpains may play a role in HD pathogenesis

Calpain 5 (CAPN5) Protein Überblick

Protein Überblick

Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3.

Genbezeichner und Symbole assoziert mit Calpain 5 Proteine (CAPN5)

  • calpain 5 (capn5)
  • calpain 5 (CAPN5)
  • calpain 5a (capn5a)
  • calpain 5 (Bm1_30735)
  • calpain 5 (Bm1_30740)
  • calpain 5 (LOAG_10085)
  • calpain 5 (LOC100351053)
  • calpain 5 (Capn5)
  • CAPN5 Protein
  • Htra3 Protein
  • MGC53448 Protein
  • MGC89353 Protein
  • nCL-3 Protein
  • zgc:153446 Protein

Bezeichner auf Proteinebene für Calpain 5 Proteine (CAPN5)

calpain 5 , calpain-5-like , calpain htra-3 , calpain-5 , new calpain 3 , nCL-3 , high-temperature requirement factor A3

GENE ID SPEZIES
380502 Xenopus laevis
419086 Gallus gallus
448405 Xenopus (Silurana) tropicalis
485175 Canis lupus familiaris
536988 Bos taurus
100394779 Callithrix jacchus
100448228 Pongo abelii
563346 Danio rerio
6101039 Brugia malayi
6101040 Brugia malayi
9947526 Loa loa
100351053 Oryctolagus cuniculus
100524513 Sus scrofa
726 Homo sapiens
12337 Mus musculus
171495 Rattus norvegicus
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