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CDH16 is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Zusätzlich bieten wir Ihnen Cadherin-16 Antikörper (159) und und viele weitere Produktgruppen zu diesem Protein an.
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Our study expands the clinical and allelic spectrum of known Retinal dystrophies genes, and reveals AGBL5, CDH16, and DNAJC17 as novel disease candidates.
In thyroid carcinomas, as determined by quantitative RT-PCR, CDH16 expression decreases in papillary, follicular, and anaplastic thyroid carcinomas, and the decrease is more pronounced than that of CDH1.
These results indicated that LIF (zeige LIF Proteine) induced multi-lineage differentiation of adult stem-like cells in kidney via cadherin 16.
Ksp-cadherin expression downregulated inrenal cell carcinoma; this cell adhesion molecule (zeige MCAM Proteine) may have role in tumour suppression
Ksp-cad is a useful tumor type associated marker for distinguishing chromophobe renal cell carcinoma (zeige MOK Proteine) and renal oncocytoma from the wide range of nonintercalated cell-related adult renal epithelial neoplasms.
The interaction of Ksp-cadherin with alpha B-crystallin (zeige CRYAB Proteine) is important for the connection of Ksp-cadherin to the cytoskeleton and thus for maintaining tissue integrity in the kidney.
study concludes that Cadherin-16 is a novel downstream target of the transcription factor Pax8 (zeige PAX8 Proteine), likely since the early steps of thyroid development, and that its expression is associated with the fully differentiated state of the thyroid cell
In the developing thyroid, CDH16 is expressed at embryonic day 10.5, 1-2 d after the main thyroid-specific transcription factors involved in thyroid cell differentiation.
identify Ksp-cadherin as the first kidney-specific promoter that has been shown to be regulated by hepatocyte nuclear factor-1 (zeige HNF1A Proteine)
Ksp-cadherin induces homotypic and Ca2 (zeige CA2 Proteine)+-dependent cell-cell adhesion that can be specifically blocked with antibodies raised against the cadherin repeats EC1 and EC2 (zeige TCF15 Proteine)
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
, kidney-specific cadherin
, Kidney-specific cadherin
, cadherin 16, KSP-cadherin, kidney-specific cadherin