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May indirectly participate in activation of the NF- kappa-B and MAPK pathways. Zusätzlich bieten wir Ihnen CXXC Finger Protein 5 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.
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recruits DNA demethylase (zeige MBD2 Antikörper) Tet2 (zeige TET2 Antikörper) to regulate TLR7 (zeige TLR7 Antikörper)/9-elicited interferon (zeige IFNA Antikörper) response in plasmacytoid dendritic cells
Data show that the peptide binding pocket of the Dishevelled 1 (Dvl1 (zeige DVL1 Antikörper)) PDZ domain (zeige INADL Antikörper) is stabilized upon CXXC finger 5 protein (CXXC5) binding.
The finding of this study indicate that the regulation of myelin genes expression by CXXC5 is important for forming myelin structure involved with axonal electrical signal transfer in the corpus callosum.
The Dishevelled (zeige DVL2 Antikörper)-binding protein CXXC5 negatively regulates cutaneous wound healing.
CXXC5 is a transcriptional activator for Flk-1, mediating BMP signaling for differentiation and migration of endothelial cell and vessel formation.
High CXXC5 expression seems to affect several steps in human leukemogenesis, including intracellular events as well as extracellular communication.
Findings suggest that overexpression of CXXC5 in C2C12 myoblasts facilitated myocyte differentiation, while RNAi interference of CXXC5 significantly inhibited the differentiation of C2C12 myoblasts.
Low CXXC5 expression is associated with acute myeloid leukemia (zeige BCL11A Antikörper).
targeting of CXXC5/RINF should be considered as a possible therapeutic strategy, especially in high-risk patients who show increased expression in AML (zeige RUNX1 Antikörper) cells compared with normal hematopoietic cells
Lack of promoter hypermethylation or somatic mutations are found in the potential tumor suppressor CXXC5 in myelodysplastic syndromes or acute myeloid leukemia (zeige BCL11A Antikörper) with deletion 5q.
RINF overexpression represents an independent molecular marker for poor prognosis in breast tumors.
RINF expression correlates with retinoid-induced differentiation of leukemic cells and with cytokine-induced myelopoiesis of normal CD34 (zeige CD34 Antikörper)(+) progenitors.
These findings suggest that CF5 plays a crucial role in ATM (zeige ATM Antikörper)-p53 (zeige TP53 Antikörper) signaling in response to DNA damage.
May indirectly participate in activation of the NF- kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells (By similarity).
CXXC-type zinc finger protein 5
, CXXC finger 5 protein
, WT1-induced Inhibitor of Dishevelled
, putative MAPK-activating protein PM08
, putative NF-kappa-B-activating protein 102
, retinoid-inducible nuclear factor
, CXXC finger 5