C-Type Lectin Domain Family 2, Member A Proteine (CLEC2A)

CLEC2A belongs to the CLEC2 family of activation-induced, natural killer gene complex-encoded C-type lectin-like receptors (Spreu et al., 2007 [PubMed 18046548]).[supplied by OMIM, May 2008].. Zusätzlich bieten wir Ihnen C-Type Lectin Domain Family 2, Member A Antikörper (43) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CLEC2A 387836 Q6UVW9
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 46 bis 51 Tage
5.743,80 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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CLEC2A Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,

Weitere Proteine zu C-Type Lectin Domain Family 2, Member A (CLEC2A) Interaktionspartnern

Human C-Type Lectin Domain Family 2, Member A (CLEC2A) Interaktionspartner

  1. PDGF (zeige PDGFA Proteine) upregulates the expression of CLEC-2 (zeige CLEC1B Proteine) on dendritic cells to induce T regulatory cells.

  2. Key residues at the membrane-distal surface of KACL, but not glycosylation, determine the functional interaction of the keratinocyte-specific C-type lectin (zeige MBL2 Proteine)-like receptor KACL with its high-affinity receptor NKp65 (zeige KLRF2 Proteine)

  3. CLEC-2 (zeige CLEC1B Proteine), unlike platelet ITAM receptors, is not regulated by proteolysis and can be used to monitor platelet-derived microparticles

  4. Keratinocytes express KACL and are capable of stimulating NKp65 (zeige KLRF2 Proteine)-expressing cells in a KACL-dependent manner.

  5. T-cell PILAR signaling through CD161 (zeige KLRB1 Proteine) supports CD3 (zeige CD3 Proteine) antibody-dependent and antigen-specific T-cell proliferation by increasing the expression of antiapoptotic Bcl-xL (zeige BCL2L1 Proteine) and induces secretion of T helper type 1 cytokines

  6. CLEC-2 (zeige CLEC1B Proteine) is the receptor for podoplanin (zeige PDPN Proteine), a sialoglycoprotein implicated in tumor-induced platelet aggregation and tumor metastasis[review]

C-Type Lectin Domain Family 2, Member A (CLEC2A) Protein Überblick

Protein Überblick

CLEC2A belongs to the CLEC2 family of activation-induced, natural killer gene complex-encoded C-type lectin-like receptors (Spreu et al., 2007

Genbezeichner und Symbole assoziert mit CLEC2A

  • C-type lectin domain family 2, member A (CLEC2A)
  • KACL Protein
  • PILAR Protein
  • UNQ5792 Protein

Bezeichner auf Proteinebene für CLEC2A

C-type lectin domain family 2 member A , INPE5792 , keratinocyte-associated C-type lectin , proliferation-induced lymphocyte-associated receptor

GENE ID SPEZIES
387836 Homo sapiens
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