C-Type Lectin Domain Family 12, Member A Proteine (CLEC12A)

CLEC12A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Zusätzlich bieten wir Ihnen CLEC12A Antikörper (68) und CLEC12A Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CLEC12A 160364 Q5QGZ9
CLEC12A 232413 Q504P2
Ratte CLEC12A CLEC12A 680338  
Direkt bei antikoerper-online bestellen
  • +49 (0)241 95 163 153
  • +49 (0)241 95 163 155
  • Online bestellen
  • orders@antikoerper-online.de

Top CLEC12A Proteine auf antikoerper-online.de

Showing 5 out of 7 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Human Cells Human His tag 50 μg Anmelden zum Anzeigen 18 bis 20 Tage
650,00 €
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 46 bis 51 Tage
4.032,65 €
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Wheat germ Human Unkonjugiert   10 μg Anmelden zum Anzeigen 7 bis 8 Tage
576,00 €
Details
HOST_Wheat germ Human GST tag   10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details

CLEC12A Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)
,

Am meisten referenzierte CLEC12A Proteine

  1. Human CLEC12A Protein expressed in Human Cells - ABIN3216398 : Chen, Floyd, Olson, Magaletti, Li, Draves, Clark: Dendritic-cell-associated C-type lectin 2 (DCAL-2) alters dendritic-cell maturation and cytokine production. in Blood 2006 (PubMed)
    Zeige alle 5 Referenzen für 3216398

Weitere Proteine zu C-Type Lectin Domain Family 12, Member A (CLEC12A) Interaktionspartnern

Human C-Type Lectin Domain Family 12, Member A (CLEC12A) Interaktionspartner

  1. Due to the absence of CLEC12A on normal haematopoietic stem cells, CLEC12A stem cell immunophenotyping may contribute to diagnosing and monitoring MDS (zeige PAFAH1B1 Proteine) patients and could furthermore add knowledge about disease propagating cells in MDS (zeige PAFAH1B1 Proteine).

  2. We propose the hypothesis that decreased expression of CLEC12A is a common denominator in the hyperinflammatory responses observed in Behcet's syndrome and gout.

  3. Antibacterial autophagy is impaired in CLEC12A-deficient cells, and this effect is exacerbated in the presence of the ATG16L1( *)300A risk allele.

  4. Upon CLL1 (zeige COLEC10 Proteine)-selective binding of this fusion protein, granulocytes acquire additional TRAIL-mediated cytotoxic activity that, importantly, potentiates antibody-mediated cytotoxicity of clinically used therapeutic antibodies

  5. We conclude the hMICL/CD123 (zeige IL3RA Proteine)-based MFC assay is a promising MRD tool in AML (zeige RUNX1 Proteine).

  6. There is a potential genetic association of CLEC12A with rheumatoid arthritis (RA). Since CLEC12A encodes for the myeloid inhibitory C-type lectin-like receptor that modulates cytokine synthesis, this receptor may contribute to the pathogenesis of RA.

  7. For production of cytotoxic T cells, transgenic DEC-205 (zeige LY75 Proteine) and Clec9A (zeige CLEC9A Proteine), but not Clec12A, are effective targets for antibody-mediated delivery of antigens for vaccination, although only in the presence of adjuvants.

  8. MICL is a negative regulator of granulocyte and monocyte function

  9. the molecular cloning, tissue distribution, and functional characterization of a novel NK cell receptor (zeige KIR2DL4 Proteine), KLRL1, from human and mouse dendritic cells [KLRL1]

  10. Expression cloning identified the antigen recognized as C-type lectin-like molecule-1, a previously undescribed transmembrane glycoprotein

Mouse (Murine) C-Type Lectin Domain Family 12, Member A (CLEC12A) Interaktionspartner

  1. Clec9A and Clec12A exhibit different intrinsic capacities to elicit MHC I and MHC II presentation following direct antigen targeting

  2. Clec12a(-/-) mice are more susceptible to Salmonella infection, supporting a role for CLEC12A in antibacterial defense pathways in vivo.

  3. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death.

  4. the molecular cloning, tissue distribution, and functional characterization of a novel NK cell receptor (zeige KLRD1 Proteine), KLRL1, from human and mouse dendritic cells [KLRL1]

  5. CLL-1 expression is also present on the CD34 (zeige CD34 Proteine)(+)CD38(-) stem- cell compartment in acute myeloid leukemia (zeige BCL11A Proteine)

  6. Anti-Clec12A mAb alone produced only moderate responses, but these were amplified by coinjecting only small amounts of LPS (zeige TLR4 Proteine) as a dendritic cell activation agent

CLEC12A Protein Überblick

Protein Überblick

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13.

Genbezeichner und Symbole assoziert mit CLEC12A

  • C-type lectin domain family 12, member A (CLEC12A)
  • C-type lectin domain family 12, member a (Clec12a)
  • C-type lectin domain family 12, member A (Clec12a)
  • CLL-1 Protein
  • CLL1 Protein
  • D230024O04 Protein
  • DCAL-2 Protein
  • KLRL1 Protein
  • MGC179455 Protein
  • Micl Protein

Bezeichner auf Proteinebene für CLEC12A

C-type lectin domain family 12, member A , C-type lectin domain family 12 member A , C-type lectin protein CLL-1 , C-type lectin superfamily , C-type lectin-like molecule-1 , dendritic cell-associated lectin 2 , myeloid inhibitory C-type lectin-like receptor , C-type lectin-like molecule 1

GENE ID SPEZIES
477697 Canis lupus familiaris
508740 Bos taurus
100053711 Equus caballus
160364 Homo sapiens
232413 Mus musculus
680338 Rattus norvegicus
Ausgewählte Anbieter für CLEC12A Proteine (CLEC12A)
Haben Sie etwas anderes gesucht?