C-Type Lectin Domain Family 10, Member A Proteine (CLEC10A)

CLEC10A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Zusätzlich bieten wir Ihnen CLEC10A Antikörper (147) und CLEC10A Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CLEC10A 10462 Q8IUN9
CLEC10A 17312 P49300
CLEC10A 64195  
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Top CLEC10A Proteine auf antikoerper-online.de

Showing 10 out of 22 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$4,244.78
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,442.50
Details
HEK-293 Cells Human Fc Tag Human CLEC10A, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$275.00
Details
Human Cells Human Fc Tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
Details
Mammalian Cells Human His tag   50 μg Anmelden zum Anzeigen 4 Days
$280.50
Details
HEK-293 Cells Human His tag Validation with Western Blot 10 μg Anmelden zum Anzeigen 12 bis 15 Tage
$345.35
Details
Human Cells Maus His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
Details
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$672.00
Details
Escherichia coli (E. coli) Maus His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$704.00
Details
Human Human His tag   10 μg Anmelden zum Anzeigen 15 bis 16 Tage
$187.50
Details

CLEC10A Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , , , ,
, , , , ,
Mouse (Murine) , ,
, , ,
Rat (Rattus)

Weitere Proteine zu C-Type Lectin Domain Family 10, Member A (CLEC10A) Interaktionspartnern

Human C-Type Lectin Domain Family 10, Member A (CLEC10A) Interaktionspartner

  1. this paper shows that key gene of intermediate proinflammatory monocytes, such as CLEC10A, is expressed three- to fourfold more in juvenile idiopathic arthritis-enthesitis-related arthritis

  2. BRAF (zeige BRAF Proteine)(V600E) mutation induces MGL ligand expression, thereby providing a direct link between oncogenic transformation and aberrant expression of immunosuppressive glycans in colorectal neoplasms.

  3. These results indicate a role of MGL as an immunomodulator within the tumour microenvironment interfering with Treg functions, suggesting its possible use in the design of anticancer vaccines.

  4. expression of GalNAc moieties mirrors the T cell activation status, and thus only highly stimulated T cells are prone to the suppressive action of MGL.

  5. MGL triggering synergized with TLR2-induced pathways, leading to elevated IL-10 (zeige IL10 Proteine) mRNA levels & enhanced TNF-alpha (zeige TNF Proteine) mRNA stability. It promoted phosphorylation of the ERK (zeige EPHB2 Proteine) & CREB (zeige CREB1 Proteine), fine-tuning the DC maturation phenotype.

  6. Described is the use of recombinant CLEC10A (CD301), a human glycoreceptor of the C-type lectin (zeige MBL2 Proteine) family, for the detection of ligands in sections from formalin-fixed, paraffin-embedded normal and cancerous mammary tissues.

  7. MGL engagement improved DC performance as antigen-presenting cells, promoting the upregulation of maturation markers, a decrease in phagocytosis, an enhancement of motility, and most importantly an increase in antigen-specific CD8 (zeige CD8A Proteine)(+) T-cell activation.

Mouse (Murine) C-Type Lectin Domain Family 10, Member A (CLEC10A) Interaktionspartner

  1. Macrophage Galactose-Type Lectin-1 Deficiency Is Associated with Increased Neutrophilia and Hyperinflammation in Gram-Negative Pneumonia

  2. Mgl1 (zeige LLGL1 Proteine)-deficient mice displayed accelerated colonic propulsion and were hypersensitive to mu receptor-mediated inhibition of colonic motility.

  3. MGL1 (zeige LLGL1 Proteine) is involved in T. crassiceps recognition and subsequent innate immune activation and resistance.

  4. The MGL1 (zeige LLGL1 Proteine) functions as an attachment and entry receptor for influenza A virus.

  5. Syk (zeige SYK Proteine) was involved in the CLR (zeige CALCR Proteine)-mediated activation of mast cells by BP

  6. Hoxc8 (zeige HOXC8 Proteine) downregulates Mgl1 (zeige LLGL1 Proteine) tumor suppressor gene expression and reduces its concomitant function on cell adhesion.

  7. The authors conclude that lectin-mediated interactions of influenza virus with the MMR (zeige MRC1 Proteine) or the MGL are required for the endocytic uptake of the virus into macrophages.

  8. mMGL1 preferentially binds Lewis X (zeige FUT4 Proteine)-conjugated soluble polyacrylamides

  9. Generation of mice deficient for macrophage galactose- and N-acetylgalactosamine-specific lectin: limited role in lymphoid and erythroid homeostasis and evidence for multiple lectins.

  10. sialoadhesin (zeige SIGLEC1 Proteine) acts as an endogenous counter-receptor for MGL1 (zeige LLGL1 Proteine)

CLEC10A Protein Überblick

Protein Überblick

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene.

Genbezeichner und Symbole assoziert mit CLEC10A

  • C-type lectin domain family 10 member A (LOC607405)
  • C-type lectin domain containing 10A (CLEC10A)
  • C-type lectin domain family 10, member A (Clec10a)
  • C-type lectin domain containing 10A (Clec10a)
  • CD301 Protein
  • CD301a Protein
  • CLEC10A Protein
  • CLECSF13 Protein
  • CLECSF14 Protein
  • HML Protein
  • HML2 Protein
  • M-ASGP-BP-1 Protein
  • Mgl Protein
  • Mgl1 Protein
  • Mgll Protein

Bezeichner auf Proteinebene für CLEC10A

C-type lectin domain family 10, member A , C-type lectin, superfamily member 14 , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 13 (macrophage-derived) , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 14 (macrophage-derived) , C-type lectin domain family 10 member A , macrophage lectin 2 (calcium dependent) , macrophage asialoglycoprotein-binding protein 1 , macrophage galactose N-acetyl-galactosamine specific lectin 1 , Gal/GalNAc-specific lectin , M-ASGP-BP , M-ASGP-BP-1 , MMGL , macrophage galactose/N-acetylgalactosamine-specific lectin , monoglyceride lipase

GENE ID SPEZIES
607405 Canis lupus familiaris
748824 Pan troglodytes
10462 Homo sapiens
17312 Mus musculus
64195 Rattus norvegicus
Ausgewählte Anbieter für CLEC10A Proteine (CLEC10A)
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