C-Type Lectin Domain Family 1, Member B (CLEC1B) ELISA Kits

Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1\\\\; MIM 602894) and NKG2D (KLRC4\\\\; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit o. Zusätzlich bieten wir Ihnen C-Type Lectin Domain Family 1, Member B Antikörper (124) und C-Type Lectin Domain Family 1, Member B Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Ratte CLEC1B CLEC1B 500336  
CLEC1B 51266 Q9P126
Anti-Maus CLEC1B CLEC1B 56760 Q9JL99
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Katalog Nr. Reaktivität Sensitivität Bereich Menge Anbieter Lieferzeit Preis Details
Human 1.22 ng/mL 1.229-300 ng/mL 96 Tests Anmelden zum Anzeigen 6 bis 8 Tage
479,81 €
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Weitere ELISA Kits für C-Type Lectin Domain Family 1, Member B Interaktionspartner

Human C-Type Lectin Domain Family 1, Member B (CLEC1B) Interaktionspartner

  1. Data (including data from studies using cells from knockout mice) suggest that CLEC2/CLEC2R signaling is dependent on thromboxane A2 generation and is potentiated by co-stimulation with different GNAQ (zeige GNAQ ELISA Kits) agonists. (CLEC2 = C-type lectin (zeige MBL2 ELISA Kits) CLEC2; CLEC2R = CLEC2 receptor; GNAQ (zeige GNAQ ELISA Kits) = guanine nucleotide-binding protein (zeige COASY ELISA Kits) G[q] subunit alpha)

  2. NZ-1 inhibits the hPDPN-CLEC-2 interaction and is also useful for anti-PA tag MAb.The minimum epitope of LpMab-13 was identified as Ala42-Asp49 of hPDPN using Western blot and flow cytometry. The combination of different epitope-possessing MAbs could be advantageous for the hPDPN-targeting diagnosis and therapy

  3. CLEC2 prevents expression of PI3K (zeige PIK3CA ELISA Kits) subunits, in a SYK (zeige SYK ELISA Kits)-dependent manner, to suppress the invasive activities of gastric cancer cells.

  4. CLEC-2 regulates Akt and MAPK downstream of PI3K and PKC, leading to phosphorylation and inhibition of GSK3alpha/beta, and enhanced platelet aggregation and secretion.

  5. Data (including data from studies using recombinant proteins) suggest that a diverse range of ligands activate platelets through activation/phosphorylation (zeige CD36 ELISA Kits) of C (zeige GP6 ELISA Kits)D36/GPVI (glycoprotein VI) and/or CLEC-2 (C-type lectin-like receptor-2).

  6. PI3K (zeige PIK3CA ELISA Kits) and Tec (zeige NR4A3 ELISA Kits) family kinases play a crucial role in the regulation of platelet activation and Syk (zeige SYK ELISA Kits) phosphorylation downstream of the CLEC-2 receptor

  7. fucoidan is a novel CLEC-2 receptor agonist that activates platelets through a SFK-dependent signaling pathway

  8. Dimerization of two phosphorylated CLEC-2 molecules leads to recruitment of the tyrosine kinase Syk via its tandem SH2 domains and initiation of a downstream signaling cascade

  9. A differential proteomic analysis of basal and rhodocytin-activated platelets with the aim of providing novel clues on CLEC-2 signaling regulation.

  10. The glycosylation sites (N120 and N134) are necessary for the surface expression of CLEC-2.

Mouse (Murine) C-Type Lectin Domain Family 1, Member B (CLEC1B) Interaktionspartner

  1. a novel mechanism of Deep vein thrombosis, whereby CLEC-2 and upregulation of podoplanin (zeige PDPN ELISA Kits) expression in the venous wall trigger thrombus formation

  2. A reciprocal interaction between CLEC-2 on megakaryocytes and PDPN (zeige PDPN ELISA Kits) on Bone marrow (BM) Fibroblastic reticular cell-like cells contributes to the periarteriolar megakaryopoietic microenvironment in mouse BM.

  3. A role for CLEC2 as a regulator of macrophage polarity and Kupffer cell polarity, lipid and glucose homeostasis

  4. Data indicate that C-type lectin-like receptor-2 (CLEC-2) is highly expressed on bone marrow megakaryocytes (Mks (zeige MKKS ELISA Kits)).

  5. Data (including data from studies in transgenic mice) suggest that a diverse range of ligands activate platelets through activation/phosphorylation of Cd36 (zeige CD36 ELISA Kits)/GPVI (zeige GP6 ELISA Kits) (glycoprotein VI) and/or Clec-2 (C-type lectin-like receptor-2).

  6. Podoplanin (zeige PDPN ELISA Kits) and CLEC-2 critically drive the formation and integrity of developing cerebral blood vessels.

  7. PI3K and Tec (zeige NR4A3 ELISA Kits) family kinases play a crucial role in the regulation of platelet activation and Syk (zeige SYK ELISA Kits) phosphorylation downstream of the CLEC-2 receptor

  8. CLEC-2 signaling promotes adhesion to Podoplanin (zeige PDPN ELISA Kits) and regulation of Podoplanin (zeige PDPN ELISA Kits) signaling, thereby contributing to lymphatic vasculature development.

  9. Under resting conditions, when FRCs are unlikely to encounter mature DCs expressing the PDPN (zeige PDPN ELISA Kits) receptor CLEC-2, PDPN (zeige PDPN ELISA Kits) endowed FRCs with contractile function and exerted tension within the reticulum.

  10. Functional studies of platelets from Ceacam2(-/-)-deficient mice (Cc2 (zeige TSG101 ELISA Kits)(-/-)) revealed that CEACAM2 serves to negatively regulate collagen glycoprotein VI (platelet) (GPVI (zeige GP6 ELISA Kits))-FcRgamma (zeige FCER1G ELISA Kits)-chain and the C-type lectinlike receptor 2 (CLEC-2) signaling

C-Type Lectin Domain Family 1, Member B (CLEC1B) Antigen-Profil

Beschreibung des Gens

Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1\; MIM 602894) and NKG2D (KLRC4\; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000

Genbezeichner und Symbole assoziert mit CLEC1B

  • C-type lectin domain family 1, member B (CLEC1B) Antikörper
  • C-type lectin domain family 1, member B (Clec1b) Antikörper
  • C-type lectin domain family 1, member B (LOC100346882) Antikörper
  • C-type lectin domain family 1, member b (Clec1b) Antikörper
  • 1810061I13Rik Antikörper
  • Clec-2 Antikörper
  • CLEC1B Antikörper
  • Clec2 Antikörper
  • CLEC2B Antikörper
  • PRO1384 Antikörper
  • QDED721 Antikörper
  • RGD1563517 Antikörper

Bezeichner auf Proteinebene für CLEC1B

C-type lectin domain family 1, member B , C-type lectin domain family 1 member B , c-type lectin domain family 1 member B-like , C-type lectin-like receptor 2 , C-type lectin-like receptor-2 , CLEC-2

GENE ID SPEZIES
465283 Pan troglodytes
486696 Canis lupus familiaris
500336 Rattus norvegicus
717404 Macaca mulatta
784092 Bos taurus
100346882 Oryctolagus cuniculus
51266 Homo sapiens
56760 Mus musculus
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