anti-CD2-Associated Protein (Cd2ap) Antikörper

Cd2ap encodes a scaffolding molecule that regulates the actin cytoskeleton. Zusätzlich bieten wir Ihnen CD2-Associated Protein Proteine (7) und CD2-Associated Protein Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
Cd2ap 23607 Q9Y5K6
Cd2ap 12488 Q9JLQ0
Cd2ap 316258  
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Top anti-CD2-Associated Protein Antikörper auf antikoerper-online.de

Showing 10 out of 47 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat lung tissue labeled with Anti-CD2AP Polyclonal Antibody (ABIN669486), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat lung tissue labeled with Anti-CD2AP Polyclonal Antibody  , Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$295.90
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB WB Image CD2AP antibody detects CD2AP protein by Western blot analysis. A. 30 µg Rat2 whole cell lysate/extract 7.5 % SDS-PAGE CD2AP antibody , dilution: 1:1000 WB Image CD2AP antibody detects CD2AP protein by Western blot analysis. A. 30 µg 293T whole cell lysate/extract B. 30 µg A431 whole cell lysate/extract C. 30 µg HeLa whole cell lysate/extract D. 30 µg HepG2 whole cell lysate/extract E. 30 µg A375 whole cell lysate/extract 7.5 % SDS-PAGE CD2AP antibody , dilution: 1:1000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of CD2AP expression in MCF7 (A), SW480 (B), mouse kidney (C), rat kidney (D) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IHC, ELISA 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of various cells, using CD2AP antibody. 100 μL Anmelden zum Anzeigen 16 Days
$323.13
Details
Human Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$384.00
Details
Ratte Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$418.00
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: CD2AP Antibody [NBP1-90626] - Staining of human cell line U-251MG shows positivity in plasma membrane & cytoplasm. Immunohistochemistry-Paraffin: CD2AP Antibody [NBP1-90626] - Staining of human colon shows strong cytoplasmic positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert IP, IHC, ELISA, WB   0.1 mg Anmelden zum Anzeigen 2 bis 6 Tage
$327.00
Details
Human Kaninchen Biotin ELISA, WB   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$683.83
Details

Cd2ap Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human ,


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Mouse (Murine) ,
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Rat (Rattus) ,


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Weitere Antikörper gegen CD2-Associated Protein Interaktionspartner

Zebrafish CD2-Associated Protein (Cd2ap) Interaktionspartner

  1. Tank1 (zeige TNKS Antikörper)/Tank2 (zeige TNKS2 Antikörper) inhibition aggravates kidney injury in the absence of CD2AP.

Human CD2-Associated Protein (Cd2ap) Interaktionspartner

  1. data suggest that CD2AP acts as a negative regulator of ICAM-1 (zeige ICAM1 Antikörper) clustering, which limits the formation of ICAM-1 (zeige ICAM1 Antikörper) adhesion complexes to prevent uncontrolled neutrophil adhesion and transcellular transmigration.

  2. CD2AP expression in renal tubules may histologically associate with tissue hypoxia and reflected recovery from CsA-mediated renal injury in nephrotic syndrome patients.

  3. data thus reveal a Golgi-traversing pathway for exosomal release of the cargo protein GPRC5B (zeige GPRC5B Antikörper) in which CD2AP facilitates the entry and LMAN2 (zeige LMAN2 Antikörper) impedes the exit of the flux, respectively.

  4. Silencing Cindr in nephrocytes led to dramatic nephrocyte functional impairment and shortened life span, as well as collapse of nephrocyte lacunar channels and effacement of nephrocyte slit diaphragms. These phenotypes could be rescued by expression of a wild-type human CD2AP gene, but not a mutant allele derived from a patient with CD2AP-associated NS.

  5. Study found a novel association of CD2AP with plasma homocysteine in participants with African ancestry and found a new variant in the candidate gene CBS (zeige CBS Antikörper) associated with homocysteine

  6. CD2AP rs9349407 polymorphism contributes to Alzheimer's disease susceptibility.

  7. discovered novel interaction candidates for CD2AP and characterized subtle yet significant differences in the recognition preferences of its three SH3 domains for c-CBL (zeige CBL Antikörper), ALIX (zeige PDCD6IP Antikörper), and RIN3 (zeige RIN3 Antikörper)

  8. we present the first demonstration that the purified SH3 domains of the CD2AP/Cin85 (zeige SH3KBP1 Antikörper) protein family are able to directly bind the p53 (zeige TP53 Antikörper) protein, and to discriminate between the two polymorphic variants P72R

  9. CD2-Associated Protein affects Abeta (zeige APP Antikörper) levels and Abeta42/Abeta40 ratio in vitro

  10. CD2AP gene variants may contribute to susceptibility to end-stage renal disease in patients with type 1 diabetes.

Mouse (Murine) CD2-Associated Protein (Cd2ap) Interaktionspartner

  1. Tank1 (zeige TNKS Antikörper)/Tank2 (zeige TNKS2 Antikörper) inhibition aggravates kidney injury in the absence of CD2AP.

  2. Bin1 (zeige BIN1 Antikörper) and CD2AP keep APP (zeige APP Antikörper) and BACE1 (zeige BACE Antikörper) apart in early endosomes by distinct mechanisms in axon and dendrites. Individuals carrying variants of either factor would slowly accumulate Abeta (zeige APP Antikörper) in neurons increasing the risk for late-onset AD.

  3. CD2AP forms a complex with GGA2 (zeige GGA2 Antikörper), a clathrin adaptor, which sorts Glut4 (zeige SLC2A4 Antikörper) to GSVs, suggesting a role for CD2AP in this process.

  4. CD2AP is the first signaling molecule associated with adult sensory axonal collateral sprouting

  5. CD2AP has role in mediating blood-brain barrier integrity and cerebrovascular roles of CD2AP could contribute to its effects on Alzheimer's disease risk.

  6. CD2-Associated Protein affects Abeta (zeige APP Antikörper) levels and Abeta42/Abeta40 ratio in vitro

  7. only the SH3 domains of CD2AP are necessary to enhance the E3 ligase activity of Cbl-3 (zeige CBLC Antikörper)/c toward Ret51 (zeige RET Antikörper)

  8. CD2AP is not involved in the regulation of type I IFNs in plasmacytoid dendritic cells. Its major function is on the actin cytoskeleton, affecting migration to local lymph nodes under conditions of inflammation.

  9. CD2AP deficiency results in the excretion of intact albumin (zeige ALB Antikörper) in knockout mice.

  10. the formation of lamellipodia is mediated by a complex of cortactin (zeige CTTN Antikörper), CD2AP, and actin capping protein (zeige TMOD4 Antikörper)

CD2-Associated Protein (Cd2ap) Antigen-Profil

Protein Überblick

This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

Genbezeichner und Symbole assoziert mit Cd2ap

  • CD2-associated protein L homeolog (cd2ap.L) Antikörper
  • CD2 associated protein (CD2AP) Antikörper
  • CD2-associated protein (cd2ap) Antikörper
  • CD2 associated protein (cd2ap) Antikörper
  • CD2-associated protein (Cd2ap) Antikörper
  • CD2 associated protein (Cd2ap) Antikörper
  • AL024079 Antikörper
  • C78928 Antikörper
  • cd2apl Antikörper
  • CMS Antikörper
  • DKFZp469E061 Antikörper
  • fj51c01 Antikörper
  • im:7153970 Antikörper
  • METS-1 Antikörper
  • Mets1 Antikörper
  • si:ch211-207n9.1 Antikörper
  • wu:fj51c01 Antikörper
  • zgc:103705 Antikörper

Bezeichner auf Proteinebene für Cd2ap

CD2-associated protein , Cas ligand with multiple Src homology 3 (SH3) domains , adapter protein CMS , cas ligand with multiple SH3 domains , hypothetical protein , SH3 domain-containing adapter protein , SH3 domain-containing adaptor protein METS-1 , mesenchyme to epithelium transition protein, SH3 domains , mesenchyme-to-epithelium transition protein with SH3 domains 1

GENE ID SPEZIES
445851 Xenopus laevis
472241 Pan troglodytes
494040 Danio rerio
705221 Macaca mulatta
100014892 Monodelphis domestica
100158527 Xenopus (Silurana) tropicalis
100172673 Pongo abelii
100341696 Oryctolagus cuniculus
100386627 Callithrix jacchus
100466982 Ailuropoda melanoleuca
100554210 Anolis carolinensis
100600076 Nomascus leucogenys
23607 Homo sapiens
771715 Gallus gallus
474928 Canis lupus familiaris
533188 Bos taurus
12488 Mus musculus
316258 Rattus norvegicus
100731393 Cavia porcellus
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