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The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. Zusätzlich bieten wir Ihnen CEBPD Antikörper (77) und CEBPD Kits (9) und viele weitere Produktgruppen zu diesem Protein an.
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Xenopus C/EBP delta plays a role in apoptotic cell death of larval-type epithelium during the stomach remodeling.
Results show that C/EBPbeta (zeige CEBPB Proteine) and C/EBPdelta actively regulate the promotor region of both splicing variants Ppargamma1sv and Ppargamma2 (zeige PPARG Proteine) in mouse adipocytes.
C/EBPdelta facilitates bacterial dissemination to the brain and enhances the immune response in the blood compartment. This study suggests that C/EBPdelta plays a detrimental role during the initial development of blood-borne brain infection.
Taken together, these results suggested that alpha1B-adrenoceptor signaling is required for bone formation and regulated cellular proliferation through a mechanism relevant to the up-regulation of CCAAT/enhancer-binding protein delta in osteoblasts and, thus, provide new evidence for the physiological importance of alpha1B-adrenoceptor signalling in bone homeostasis
The C/EBPdelta in the brain drives the inflammatory response and contributes to bacterial dissemination during pneumococcal meningitis. C/EBPdelta does, however, not affect clinical parameters of the disease and does not confer a survival benefit.
CEBPA (zeige CEBPA Proteine), CEBPB (zeige CEBPB Proteine) and CEBPD regulate proliferation and differentiation of chondrocytes.
SOCS3 (zeige SOCS3 Proteine) is an inflammatory enhancer in IgG immune complex-treated macrophages by increasing C/EBPD activity.
This study provides the first evidence that ZNF179 (zeige RNF112 Proteine), PLZF (zeige ZBTB16 Proteine), IGFBP3 (zeige IGFBP3 Proteine), and BIK (zeige BIK Proteine) contributed to the novel CEBPD-induced antiapoptotic feature of astrocytes.
a novel biological function for C/EBPdelta in promoting the response to radiation-induced DNA-damage and in protecting hematopoietic and intestinal tissues from radiation-induced injury
Studied role of C/EBPdelta in the development of renal tubulointerstitial fibrosis by subjecting 8- to 12-week-old C/EBPdelta-deficient mice and age- and sex-matched wild-type controls to the unilateral ureteral obstruction model.
C/EBP delta is a mediator of the pathway from p-Stat3 (zeige STAT3 Proteine) to myostatin (zeige MSTN Proteine) because its knockout of C/EBP delta inhibits myostatin (zeige MSTN Proteine) expression and suppresses muscle wasting.
These findings identify a molecular mechanism by which ERalpha (zeige ESR1 Proteine) signaling reduces the aggressiveness of cancer cells, and demonstrate that C/EBPdelta can have different functions in different types of cancer.
CREB (zeige CREB1 Proteine) overexpression increased CCAAT-enhancer-binding protein-delta (C/EBPdelta) levels to cause myeloid differentiation arrest, and the silencing of CREB (zeige CREB1 Proteine)-C/EBPdelta axis restored myeloid terminal differentiation
Data suggest that proinflammatory cytokine interleukin-1beta (IL1B (zeige IL1B Proteine)) up-regulates hepcidin (zeige HAMP Proteine) expression in hepatocytes; inflammation induces IL1B (zeige IL1B Proteine) production in Kupffer cells and hepatocytes; IL1B (zeige IL1B Proteine) up-regulates CEBPD (CCAAT/enhancer binding protein delta) expression in hepatocytes; up-regulation of CEBPD expression up-regulates hepcidin (zeige HAMP Proteine) transcription.
the C/EBPD binding site is required for RU486-mediated activation of the CHOP (zeige DDIT3 Proteine) promoter.
Results suggest that CCAAT/enhancer binding protein delta (CEBPD) could be a useful diagnostic marker and therapeutic target in hepatocellular carcinoma (HCC (zeige FAM126A Proteine)).
CEBPD amplification and overexpression is associated with urothelial carcinoma.
Knock-down of C/EBPdelta expression in pericytes following immune stimulation increased chemokine (zeige CCL1 Proteine) and adhesion molecule (zeige NCAM1 Proteine) expression.
We have discovered the CEBPD-hypoxia-inducible factor-1 (HIF-1 (zeige HIF1A Proteine)) pathway as a new HIF-1 (zeige HIF1A Proteine)-regulating fundamental mechanism in tubular epithelial cells for the cellular protection against kidney injury.
Authors found that CK2 (zeige CSNK2A1 Proteine) bound to C/EBPdelta, which might help to target CK2 (zeige CSNK2A1 Proteine) to the transcriptional machinery where it can phosphorylate other transcription factors or co-activators.
Data indicate that dysfunction of the Rho-associated kinase (zeige ROCK1 Proteine) 2 (Rock2 (zeige ROCK2 Proteine))-p-GSK3beta/beta-catenin (zeige CTNNB1 Proteine)-CCAAT/enhancer-binding protein delta (CEBPD) regulatory circuitry may contribute to the tumorigenic characteristic of hepatocellular carcinoma (HCC (zeige FAM126A Proteine)).
Elevated C/EBPdelta can induce the adipogenesis in the fibroblasts of cattle.
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11.
CCAAT/enhancer-binding protein delta
, c/EBP delta
, c/EBP-related protein 3
, nuclear factor NF-IL6-beta
, transcription factor CELF
, CCAAT/enhancer binding protein delta
, binding protein (C/EBP), delta
, CCAAT-enhancer binding protein delta
, X. C/EBP delta-2
, X. C/EBP delta-1
, C/EBP delta
, cebpd, CCAAT/enhancer binding protein (C/EBP), delta
, CCAAT/enhancer binding protein (C/EBP), delta