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The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. Zusätzlich bieten wir Ihnen CEBPA Kits (31) und CEBPA Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 154 products:
Human Polyclonal CEBPA Primary Antibody für EIA, FACS - ABIN951460
Twu, Hsieh, Lin, Tzeng, Sun, Yu: Phosphorylation status of transcription factor C/EBPalpha determines cell-surface poly-LacNAc branching (I antigen) formation in erythropoiesis and granulopoiesis. in Blood 2010
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Human Monoclonal CEBPA Primary Antibody für FACS, ICC - ABIN269606
Ferrari-Amorotti, Keeshan, Zattoni, Guerzoni, Iotti, Cattelani, Donato, Calabretta: Leukemogenesis induced by wild-type and STI571-resistant BCR/ABL is potently suppressed by C/EBPalpha. in Blood 2006
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Chicken Polyclonal CEBPA Primary Antibody für IHC, WB - ABIN2787465
Singh, Trivedi, Behre: C/EBPalpha S248A mutation reduces granulocytic differentiation in human leukemic K562 cells. in Biochemical and biophysical research communications 2008
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Human Polyclonal CEBPA Primary Antibody für FACS, WB - ABIN653431
Nanri, Uike, Kawakita, Iwanaga, Mitsuya, Asou: A family harboring a germ-line N-terminal C/EBPalpha mutation and development of acute myeloid leukemia with an additional somatic C-terminal C/EBPalpha mutation. in Genes, chromosomes & cancer 2010
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Human Monoclonal CEBPA Primary Antibody für FACS, ELISA - ABIN969507
Geest, Buitenhuis, Vellenga, Coffer: Ectopic expression of C/EBPalpha and ID1 is sufficient to restore defective neutrophil development in low-risk myelodysplasia. in Haematologica 2009
Human Monoclonal CEBPA Primary Antibody für ICC, FACS - ABIN969048
Jin, Zhang, Yan, Liu, Wang, Ge, Zhai: C/EBPalpha regulates SIRT1 expression during adipogenesis. in Cell research 2010
Cow (Bovine) Polyclonal CEBPA Primary Antibody für WB - ABIN2792649
Zhu, Qian, Levy: CCAAT/enhancer-binding protein alpha (C/EBPalpha) activates transcription of the human microsomal epoxide hydrolase gene (EPHX1) through the interaction with DNA-bound NF-Y. in The Journal of biological chemistry 2004
the importance of C/EBPalpha for neutrophil maturation, its role in myeloid priming of hematopoietic stem and progenitor cells, and its indispensable requirement for AML (zeige RUNX1 Antikörper) development.
found significantly higher frequencies for NPM1 (zeige NPM1 Antikörper)-mutated 24.2 % and CEBPA-mutated 12.1 %
results demonstrate that the low-level expression of human ACAT2 gene with specific CpG-hypomethylated promoter is regulated by the C/EBP transcription factors in monocytic cells, and imply that the lowly expressed ACAT2 catalyzes the synthesis of certain CE/SE that are assembled into lipoproteins for the secretion
Our study highlighted two novel promoter KLF1 and 3'-region C/EBPalpha motifs in the phenylalanine hydroxylase (PAH) gene which decrease transcription in vitro and, thus, could be considered as PAH expression modifiers.
The QA repeat domain of TCERG1 (zeige TCERG1 Antikörper) is required for relocalization of CEBPalpha.
In the CCAAT/enhancer binding protein alpha gene, no mutations were detected but a known polymorphism (c.584_589dup ACCCGC) was observed in 26 (28.3%) patients.
The p53 (zeige TP53 Antikörper)-KLF4 (zeige KLF4 Antikörper)-CEBPA axis is deregulated in AML (zeige RUNX1 Antikörper) but can be functionally restored by conventional chemotherapy and novel p53 (zeige TP53 Antikörper) activating treatments.
C/EBPalpha inhibited breast cancer cell growth via a novel miR (zeige MLXIP Antikörper)-134/CREB (zeige CREB1 Antikörper) signaling pathway.
C/EBP-alpha was primarily expressed in hepatocytes in normal liver, but its expression decreased significantly in liver fibrosis
The efficient repression of E2F (zeige E2F1 Antikörper) dependent S-phase genes and the activation of differentiation genes reside in the balanced DNA binding capacity of C/EBP alpha.
the DNA sequences to which EVI1 (zeige MECOM Antikörper) binds at +35 and +37 kb and show that mutation of one of these releases Cebpa from EVI1 (zeige MECOM Antikörper)-induced suppression.
Cebpa enhancers and silencers in a transcriptional model have roles in hematopoietic lineage specification
Data show that CCAAT-enhancer-binding protein-alpha (C/EBPalpha) directly regulates Kruppel-like factor 4 (Klf4 (zeige KLF4 Antikörper)) expression and increasing the levels of histone demethylase (zeige MBD2 Antikörper) Lsd1 (zeige KDM1A Antikörper) and transcription factor Brd4 (zeige BRD4 Antikörper) in B cell.
The findings demonstrate a critical role for the +37 kb Cebpa enhancer for hematopoietic-specific Cebpa expression, with enhancer deletion leading to impaired myelopoiesis and potentially preleukemic progenitor expansion.
Data indicate that miR (zeige MLXIP Antikörper)-25 is a novel negative regulator of adipocyte differentiation and it suppressed 3T3-L1 adipogenesis by targeting KLF4 (zeige KLF4 Antikörper) and C/EBPalpha, which provides novel insights into the molecular mechanism of miRNA-mediated cellular differentiation.
MYB (zeige MYB Antikörper) and C/EBPalpha activities are inter-dependent in controlling Flt3 (zeige FLT3 Antikörper) expression to influence lineage commitment of multipotential progenitors.
Data indicate that white adipose tissue from IgE receptor FcR1-deficient Fcer1a (zeige FCER1A Antikörper)(-/-) mice showed an increased expression of CCAAT-enhancer-binding protein-alpha (C-EBPalpha) and peroxisome proliferator-activated receptor-gamma (PPARgamma (zeige PPARG Antikörper)).
miR (zeige MLXIP Antikörper)-223 regulates adipocyte and osteoblast differentiation through a novel C/EBPs/miR (zeige MLXIP Antikörper)-223/FGFR2 (zeige FGFR2 Antikörper) regulatory feedback loop.
Data (including data from studies in transgenic/mutant mice) suggest Cebpa (CCAAT-enhancer binding protein alpha) in myeloid cells is down-regulated in type 2 diabetes resulting in poor maturation of Gr-1 (zeige GSR Antikörper)+ (chemokine receptor (zeige CCR1 Antikörper)) myeloid cells.
C/ebpalpha plays a role in liver growth regulation via the p53 (zeige TP53 Antikörper) pathway.
Dnmt1 (zeige DNMT1 Antikörper) is required for hematopoietic stem and progenitor cells maintenance via cebpa regulation during definitive hematopoiesis in zebrafish
Data suggest that upregulation of 10-formyltetrahydrofolate dehydrogenase (FDH (zeige ALDH1L1 Antikörper)) involving CEBPalpha helps relieve embryonic oxidative stress induced (zeige SQSTM1 Antikörper) by ethanol exposure.
Bmi1 (zeige BMI1 Antikörper) acts immediately downstream of CCAAT enhancer binding protein-alpha to regulate the survival and self-renewal of hematopoietic stem cells and contribute to the erythropoietic dysplasia.
Results provide first evidence that sumoylation of Cebp-alpha (via SUMO1 (zeige SUMO1 Antikörper), SUMO2 (zeige SUMO2 Antikörper), and SUMO3 (zeige SUMO3 Antikörper)) might contribute to cell fate decision of myelo-erythroid progenitor cells in intermediate cell mass during primitive [extramedullary] hematopoiesis.
An evolutionarily conserved PTEN (zeige PTEN Antikörper)-C/EBPalpha-CTNNA1 (zeige CTNNA1 Antikörper) axis controls myeloid development and transformation.
a C/EBP recognition sequence in the proximal promoter region of C/EBPalpha is essential for IL-6 (zeige IL6 Antikörper)-mediated repression
These results suggest that the CEBPA gene is a strong candidate gene that affects carcass traits in Qinchuan cattle.
Expressions of C-EBPalpha and myostatin (zeige MSTN Antikörper) in muscles were higher in the concentrate-fed group than in the grass hay (zeige GTF2H5 Antikörper)-fed group.
C/EBPalpha is an essential regulatory factor for perilipin5 transcription and suggest that fasting stimulates perilipin5 transcription through influencing C/EBPalpha expression.
The differential expression of specific CEBPA/B isoforms observed in maturing follicles and CL may contribute to changes in follicular cell differentiation and increasing steroidogenic capacity.
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
CCAAT/enhancer-binding protein alpha
, C/EBP alpha
, CAAT/enhancer-binding protein DNA-binding protein
, CAAT/enhancer-binding protein, DNA-binding protein
, CCAAT/enhancer binding protein, alpha
, c/EBP alpha
, CCAAT/enhancer binding protein alpha