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The BAZ1A gene encodes the accessory subunit of the ATP-dependent chromatin assembly factor (ACF), a member of the ISWI ('imitation switch') family of chromatin remodeling complexes (summarized by Racki et al., 2009 [PubMed 20033039]).[supplied by OMIM, Apr 2010].. Zusätzlich bieten wir Ihnen BAZ1A Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal BAZ1A Primary Antibody für IP, WB - ABIN253180
Aydin, Marteijn, Ribeiro-Silva, Rodríguez López, Wijgers, Smeenk, van Attikum, Poot, Vermeulen, Lans: Human ISWI complexes are targeted by SMARCA5 ATPase and SLIDE domains to help resolve lesion-stalled transcription. in Nucleic acids research 2014
Show all 2 Pubmed References
Human Polyclonal BAZ1A Primary Antibody für IHC, IHC (p) - ABIN4277647
Dowdle, Mehta, Kass, Vuong, Inagaki, Egli, Jasin, Keeney: Mouse BAZ1A (ACF1) is dispensable for double-strand break repair but is essential for averting improper gene expression during spermatogenesis. in PLoS genetics 2013
Human Monoclonal BAZ1A Primary Antibody für ELISA, WB - ABIN524603
Sheu, Choi, Yildiz, Tsai, Shaul, Wang, Shih: The roles of human sucrose nonfermenting protein 2 homologue in the tumor-promoting functions of Rsf-1. in Cancer research 2008
Baz1a deficiency causes male-specific sterility in accord with its high expression in male germ cells, where it displays dynamic, stage-specific patterns of chromosomal localization.
Study reports de novo mutation in BAZ1A, in a patient with a syndromic form of intellectual disability (ID). This mutation affects the expression of genes involved in several biological pathways such as vitamin D regulation, Wnt (zeige WNT2 Antikörper) signaling, and postsynaptic signaling. Data point to an important role for BAZ1A in neurodevelopment, and highlight a possible link for BAZ1A to ID.
CHD3.1 and ACF1-SNF2H (zeige SMARCA5 Antikörper) display counteractive activities but similar histone affinities.
ISWI (zeige SMARCA1 Antikörper) proteins Snf2H (zeige SMARCA5 Antikörper), Snf2L (zeige SMARCA1 Antikörper) as well as Acf1 accumulate at UV-induced DNA damage sites within tens of seconds and reach a plateau after a few minutes.
hACF1-containing factors are more generally involved in the DNA damage response.
The ACF1 and its complexes play important roles in DNA double-strand breaks (DSBs) repair.
The data support a model in which the human ACF (zeige A1CF Antikörper) anf (zeige NPPA Antikörper) yeast RSC remodeling enzymes move nucleosomes to new locations by a general sequence-independent mechanism.
ACF1 alters the remodeling strategy of SNF2h (zeige SMARCA5 Antikörper)
Has a critical role in the transcriptional repression of specific nuclear hormone receptor (zeige NR0B1 Antikörper)-regulated genes.
The BAZ1A gene encodes the accessory subunit of the ATP-dependent chromatin assembly factor (ACF), a member of the ISWI ('imitation switch') family of chromatin remodeling complexes (summarized by Racki et al., 2009
bromodomain adjacent to zinc finger domain, 1A
, bromodomain adjacent to zinc finger domain protein 1A
, bromodomain adjacent to zinc finger domain protein 1A-like
, gene trap locus 5
, ATP-dependent chromatin remodeling protein
, ATP-dependent chromatin-remodeling protein
, ATP-utilizing chromatin assembly and remodeling factor 1
, CHRAC subunit ACF1
, williams syndrome transcription factor-related chromatin-remodeling factor 180
, ATP-utilizing chromatin assembly factor 1