anti-Baculoviral IAP Repeat-Containing 6 (BIRC6) Antikörper

BIRC6 encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. Zusätzlich bieten wir Ihnen BIRC6 Kits (9) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
BIRC6 57448 Q9NR09
BIRC6 313876  
BIRC6 12211 O88738
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Top anti-BIRC6 Antikörper auf antikoerper-online.de

Showing 10 out of 68 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), IP, IHC, PLA, WB Detection of Human BIRC6/Apollon by Western Blot and Immunoprecipitation using ABIN152603. Samples: A) Whole cell lysate (WCL) and S100 extract (S100) from HeLa cells. B) Whole cell lysate (10 mg) from HeLa cells. Chemiluminescence with an exposure time of 10 minutes. B) Immunoprecipitate was resolved by SDS-PAGE and stained with Coomassie Blue. The band that is BIRC6 was confirmed by mass spectrometry. Immunohistochemistry-Paraffin: BIRC6 Antibody [ABIN152603] - Human breast carcinoma. Antibody used at a dilution of 1:5,000 (0.2ug/ml). 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$486.94
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$221.76
Details
Hund Maus Unkonjugiert IF, WB Western blot analysis of BRUCE on a SW-13 cell lysate (Human adrenal gland carcinoma, ATCC CCL-105). Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti-BRUCE antibody. Immunofluorescence staining of HeLa cells (Human cervical epitheloid carcinoma, ATCC CCL-2.2). 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$154.07
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: BIRC6 Antibody [ABIN42847340] - Detection of Human BIRC6/Apollon byImmunohistochemistry. Sample: FFPE section of humanovarian tumor. Antibody: Affinity purified rabbit anti-BIRC6/Apollon used at a dilution of1:250. Detection: DAB staining. Detection of Human BIRC6/Apollon byImmunohistochemistry. Sample: FFPE section of humanmetastatic lymph node. Antibody: Affinity purified rabbit anti-BIRC6/Apollon used at a dilution of1:250. Detection: DAB staining. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$538.13
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$221.76
Details
Human Kaninchen Unkonjugiert EIA, IHC (p)   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$375.38
Details
Human Ziege Unkonjugiert IHC (p), ELISA 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p) Formalin-fixed and paraffin embedded human esophageal carcinoma labeled with Anti APOLLON/BIRC6 Polyclonal Antibody, Unconjugated (ABIN687292) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$295.90
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Fledermaus Ziege Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Rind (Kuh) Ziege Unkonjugiert ELISA, ICC, IF   0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$317.63
Details

BIRC6 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-BIRC6 Antikörper

  1. Human Polyclonal BIRC6 Primary Antibody für ICC, IF - ABIN4284734 : Dong, Lin, Low, Vucic, English, Yee, Murray, Lam, Ling, Lam, Gout, Wang: Elevated expression of BIRC6 protein in non-small-cell lung cancers is associated with cancer recurrence and chemoresistance. in Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2013 (PubMed)
    Show all 4 Pubmed References

  2. Dog (Canine) Monoclonal BIRC6 Primary Antibody für IF, WB - ABIN968409 : Hauser, Bardroff, Pyrowolakis, Jentsch: A giant ubiquitin-conjugating enzyme related to IAP apoptosis inhibitors. in The Journal of cell biology 1998 (PubMed)

  3. Cow (Bovine) Polyclonal BIRC6 Primary Antibody für ELISA, ICC - ABIN4284735 : Lopergolo, Pennati, Gandellini, Orlotti, Poma, Daidone, Folini, Zaffaroni: Apollon gene silencing induces apoptosis in breast cancer cells through p53 stabilisation and caspase-3 activation. in British journal of cancer 2009 (PubMed)

  4. Human Polyclonal BIRC6 Primary Antibody für ICC, IF - ABIN152603 : Aharinejad, Andrukhova, Lucas, Zuckermann, Wieselthaler, Wolner, Grimm: Programmed cell death in idiopathic dilated cardiomyopathy is mediated by suppression of the apoptosis inhibitor Apollon. in The Annals of thoracic surgery 2008 (PubMed)

Weitere Antikörper gegen BIRC6 Interaktionspartner

Human Baculoviral IAP Repeat-Containing 6 (BIRC6) Interaktionspartner

  1. AVEN (zeige AVEN Antikörper) and BIRC6 are inhibited by combination therapy of miR (zeige MLXIP Antikörper)-30e and proanthocyanidin in glioblastoma stem cells

  2. Apollon expression is associated with the biological characteristics of esophageal squamous cell carcinoma (ESCC), and may be a valuable prognostic factor and a novel chemotherapeutic target for ESCC treatment.

  3. Apollon role in the multidrug resistance of human chronic myelogenous leukemia cells

  4. Apollon gene silencing can induce apoptosis and growth impairment in HeLa cells. In this regard, apollon can be considered a candidate therapeutic target in HeLa cells as a positive human papillomavirus cancer cell line.

  5. BRUCE protein was detected in 82% of tumors and tumor progression stage and invasion depth correlated significantly with BRUCE protein expression

  6. Results show that in addition to the scaffolding function in complex formation, BRUCE has an E3 ligase function to promote BRIT1 (zeige MCPH1 Antikörper) deubiquitination by USP8 (zeige USP8 Antikörper) leading to accumulation of BRIT1 (zeige MCPH1 Antikörper) at DNA double-strand break.

  7. BIRC6 overexpression is a predictor of poor prognosis in colorectal cancer and could be a potential target for colorectal cancer therapy.

  8. The study demonstrates that the T allele of the rs2754511 in the BIRC6 gene plays a protective role in pseudoexfoliative glaucoma patients of the Pakistani population.

  9. Humanin signaling pathway via htHNR/JAKs/STAT3 (zeige STAT3 Antikörper) increased the expression levels of mRNA and protein of Apollon/Bruce, an unusual member of the inhibitors of apoptosis proteins

  10. BRUCE acts as a scaffold, bridging the ubiquitin-specific peptidase 8 (USP8 (zeige USP8 Antikörper)) and BRIT1 (zeige MCPH1 Antikörper) in a complex to coordinate USP8 (zeige USP8 Antikörper)-catalyzed deubiquitination of BRIT1 (zeige MCPH1 Antikörper).

Cow (Bovine) Baculoviral IAP Repeat-Containing 6 (BIRC6) Interaktionspartner

  1. The results of this study reveal the importance of BIRC6 expression for embryo survival during bovine preimplantation embryo development.

Mouse (Murine) Baculoviral IAP Repeat-Containing 6 (BIRC6) Interaktionspartner

  1. Humanin signaling pathway via htHNR/JAKs/STAT3 (zeige STAT3 Antikörper) increased the expression levels of mRNA and protein of Apollon/Bruce, an unusual member of the inhibitors of apoptosis proteins

  2. BRUCE acts as a scaffold, bridging the ubiquitin-specific peptidase 8 (USP8 (zeige USP8 Antikörper)) and BRIT1 (zeige MCPH1 Antikörper) in a complex to coordinate USP8 (zeige USP8 Antikörper)-catalyzed deubiquitination of BRIT1 (zeige MCPH1 Antikörper).

  3. BRUCE protects cells against apoptosis and functions as an inhibitor of apoptosis.

  4. BRUCE is broadly expressed in embryonic, extraembryonic, and adult mouse tissues, this bifunctional protein might play a unique role in normal trophoblast differentiation and embryonic survival

  5. p53 (zeige TP53 Antikörper) is a downstream effector of Bruce, and, in response to loss of Bruce function, p53 (zeige TP53 Antikörper) activates Pidd (zeige PIDD Antikörper)/caspase-2 (zeige CASP2 Antikörper) and Bax (zeige BAX Antikörper)/Bak (zeige BAK1 Antikörper), leading to mitochondrial apoptosis

  6. Birc6 plays a role in cell division

  7. These results establish a previously unrecognized link between NFAT (zeige NFATC1 Antikörper) signaling and regulation of IAP (zeige ALPI Antikörper) expression and are the first to identify a signaling pathway that increases BRUCE expression.

BIRC6 Antigen-Profil

Protein Überblick

This gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein inhibits apoptosis by facilitating the degradation of apoptotic proteins by ubiquitination.

Genbezeichner und Symbole assoziert mit BIRC6

  • baculoviral IAP repeat containing 6 (BIRC6) Antikörper
  • baculoviral IAP repeat-containing 6 (Birc6) Antikörper
  • baculoviral IAP repeat containing 6 (birc6) Antikörper
  • A430032G04Rik Antikörper
  • A430040A19Rik Antikörper
  • AA501170 Antikörper
  • apollon Antikörper
  • BIRC6 Antikörper
  • Bruce Antikörper
  • D630005A10Rik Antikörper
  • mKIAA1289 Antikörper

Bezeichner auf Proteinebene für BIRC6

BIR repeat-containing ubiquitin-conjugating enzyme , baculoviral IAP repeat-containing 6 , baculoviral IAP repeat-containing protein 6 , ubiquitin-conjugating BIR domain enzyme apollon , ubiquitin-conjugating BIR-domain enzyme apollon , baculoviral IAP repeat-containing 6 (apollon) , apollon , baculovirus inhibitor of apoptosis repeat containing ubiquitin-conjugating enzyme , baculovirus inhibitor of apoptosis repeat containing ubiquitin-conjugating enzyme; accccbaculoviral IAP repeat-containing 6

GENE ID SPEZIES
57448 Homo sapiens
313876 Rattus norvegicus
796547 Danio rerio
100135722 Xenopus (Silurana) tropicalis
475718 Canis lupus familiaris
534211 Bos taurus
709443 Macaca mulatta
12211 Mus musculus
100027051 Monodelphis domestica
100448259 Pongo abelii
100484115 Ailuropoda melanoleuca
421463 Gallus gallus
100070568 Equus caballus
100225419 Taeniopygia guttata
100079899 Ornithorhynchus anatinus
100342432 Oryctolagus cuniculus
Ausgewählte Anbieter für anti-BIRC6 (BIRC6) Antikörper
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