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The protein encoded by BRAP was identified by its ability to bind to the nuclear localization signal of BRCA1 and other proteins. Zusätzlich bieten wir Ihnen BRAP Proteine (4) und BRAP Kits (3) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal BRAP Primary Antibody für WB - ABIN1881119
Fulcher, Roth, Fatima, Alvisi, Jans: The BRCA-1 binding protein BRAP2 is a novel, negative regulator of nuclear import of viral proteins, dependent on phosphorylation flanking the nuclear localization signal. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010
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Expression of BRAP is increased in esophageal squamous cell carcinoma samples compared with non-tumor esophageal tissues; increased expression correlates with reduced patient survival time and promotes metastasis of xenograft tumors in mice.
that BRAP plays an important role in airway inflammation and its overexpression may regulate NE-induced MUC5AC hypersecretion in HBE16 cells via the EGFR (zeige EGFR Antikörper)/ERK (zeige EPHB2 Antikörper)/NF-kappaB (zeige NFKB1 Antikörper) signaling pathway
Together the results indicate for the first time that BRAP2 may play an important NRNI role in germ cells of the testis, with an additional, scaffold/structural role in mature spermatozoa.
BRAP gene may confer vulnerability for schizophrenia in Han Chinese population.
ectopic expression of BRAP2 inhibits nuclear localization of HMG20A (zeige HMG20A Antikörper) and NuMA1 (zeige NUMA1 Antikörper), and prevents nuclear envelope accumulation of SYNE2 (zeige SYNE2 Antikörper).
genetic association studies in population of Chinese Han young adults in Beijing: Data suggest that 2 SNPs in BRAP (rs11066001; rs3782886) are associated with decreased risk of metabolic syndrome in this population.
BAP1 (zeige RNF2 Antikörper) expression closely correlates with age, clinical stage, pathologic differentiation and histological type in colorectal cancer (CRC (zeige CALR Antikörper)). BAP1 (zeige RNF2 Antikörper) may serve as a novel prognostic biomarker for CRC (zeige CALR Antikörper).
Brap2 regulates temporal control of NF-kappaB (zeige NFKB1 Antikörper) localization mediated by inflammatory response.
The BRAP polymorphism may not play an important role in ischemic stroke in the Taiwanese population.
The dominant effect of prolonged USP15 (zeige USP15 Antikörper) depletion upon signal amplitude is due to a decrease in CRAF (zeige RAF1 Antikörper) levels while allowing for the possibility that USP15 (zeige USP15 Antikörper) may also function to dampen MAPK (zeige MAPK1 Antikörper) signaling through direct stabilization of BRAP.
A molecular complex composed of Nde1, Lis1 (zeige PAFAH1B1 Antikörper), and Brap regulates the dynamic MAPK (zeige MAPK1 Antikörper) signaling threshold in a spatially dependent fashion.
p21 (zeige D4S234E Antikörper) Ras/Imp regulate cytokine production and migration in CD4 (zeige CD4 Antikörper) T cells
The protein encoded by this gene was identified by its ability to bind to the nuclear localization signal of BRCA1 and other proteins. It is a cytoplasmic protein which may regulate nuclear targeting by retaining proteins with a nuclear localization signal in the cytoplasm.
BRCA1 associated protein
, BRCA1-associated protein
, BRCA1-associated protein-like
, brca1-associated protein
, RING finger protein 52
, galectin-2-binding protein
, impedes mitogenic signal propagation
, renal carcinoma antigen NY-REN-63