anti-BCL2-Associated Athanogene 2 (BAG2) Antikörper

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. Zusätzlich bieten wir Ihnen BAG2 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
BAG2 9532 O95816
BAG2 213539 Q91YN9
BAG2 690038  
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Top anti-BAG2 Antikörper auf antikoerper-online.de

Showing 10 out of 90 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-BAG2 Antibody Titration: </b>1.25ug/ml<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB BAG2 Antibody (C-term) (ABIN657974) western blot analysis in NCI-H460 cell line lysates (35 µg/lane). This demonstrates the BAG2 antibody detected the BAG2 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti- BAG2 Picoband antibody,IHC(P) IHC(P): Rat Testis Tissue Anti- BAG2 Picoband antibody,IHC(P) IHC(P): Mouse Testis Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Ziege Unkonjugiert ELISA, WB ABIN184625 (0.3µg/ml) staining of Hela lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$326.89
Details
Human Maus Unkonjugiert WB BAG2 monoclonal antibody (M01), clone 6E12 Western Blot analysis of BAG2 expression in HeLa. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Ziege Unkonjugiert ELISA, WB Western Blot: BAG2 Antibody [ABIN250477] - ABIN250477 (0.3ug/ml) staining of Hela lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western Blot: BAG2 Antibody [ABIN250477] - (0.3ug/ml) staining of Hela lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC (p), WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Human Kaninchen Unkonjugiert WB Anti-BAG2 antibody, Western blotting Lane 1: Rat Testis Tissue Lysate Lane 2: HELA Cell Lysate Lane 3: A549 Cell Lysate Lane 4: A431 Cell Lysate 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Ziege Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$375.38
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: BAG2 Antibody [NBP1-59087] - Lane 1: 20ug untransfected human Saos2 cells Lane 2: 20ug siRUVBL transfected human. Western Blot: BAG2 Antibody [NBP1-59087] - Sample Tissue: Human HepG2 Antibody Dilution: 1.0 ug/ml 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$408.19
Details

BAG2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-BAG2 Antikörper

  1. Human Polyclonal BAG2 Primary Antibody für ICC, IF - ABIN4282947 : Dai, Qian, Li, McDonough, Borchers, Huang, Takayama, Younger, Ren, Cyr, Patterson: Regulation of the cytoplasmic quality control protein degradation pathway by BAG2. in The Journal of biological chemistry 2005 (PubMed)
    Show all 2 Pubmed References

  2. Cow (Bovine) Polyclonal BAG2 Primary Antibody für IHC, WB - ABIN2775278 : Arndt, Daniel, Nastainczyk, Alberti, Höhfeld: BAG-2 acts as an inhibitor of the chaperone-associated ubiquitin ligase CHIP. in Molecular biology of the cell 2005 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal BAG2 Primary Antibody für IHC, IHC (p) - ABIN4282948 : Gupta, Tahrir, Knezevic, White, Gordon, Cheung, Khalili, Feldman: GRP78 Interacting Partner Bag5 Responds to ER Stress and Protects Cardiomyocytes From ER Stress-Induced Apoptosis. in Journal of cellular biochemistry 2016 (PubMed)

Weitere Antikörper gegen BAG2 Interaktionspartner

Human BCL2-Associated Athanogene 2 (BAG2) Interaktionspartner

  1. A comprehensive review of the structure, functions, and protein interactions of BAG2

  2. Data show that BAG2 Inhibits CHIP-Mediated HSP72 (zeige HSPA1A Antikörper) ubiquitination in aged cells.

  3. repression of BAG2 expression or BAG2 activity by cold-sensitive pathways, as modeled in undifferentiated and differentiated cells, respectively, may be a causal factor in the accumulation of cytotoxic hyperphosphorylated tau protein.

  4. NF-kappaB (zeige NFKB1 Antikörper)-mediated modulation of BAG2 expression regulates the shift between the neurotrophic and neurotoxic effects of Abeta1-42.

  5. Thus, BAG2 promotes mutant p53 (zeige TP53 Antikörper) accumulation and gain-of-function in tumor growth, metastasis and chemoresistance.

  6. This study showed that BAG2 (Bcl-2 (zeige BCL2 Antikörper) associated athanogene family protein 2) and BAG5 (zeige BAG5 Antikörper) (Bcl-2 (zeige BCL2 Antikörper)-associated athanogene family protein 5 (zeige CAPS Antikörper)) stabilise pathogenic ataxin3-80Q by inhibiting its ubiquitination

  7. we measured the binding of human Hsp72 (HSPA1A (zeige HSPA1A Antikörper)) to BAG1 (zeige BAG1 Antikörper), BAG2, BAG3 (zeige BAG3 Antikörper), and the unrelated NEF Hsp105 (zeige HSPH1 Antikörper). These studies revealed a clear hierarchy of affinities: BAG3 (zeige BAG3 Antikörper) > BAG1 (zeige BAG1 Antikörper) > Hsp105 (zeige HSPH1 Antikörper) >> BAG2.

  8. this data correlate BAG2 to PINK1 (zeige PINK1 Antikörper) for the first time, strengthening the important role of BAG2 in Parkinson disease -related neurodegeneration.

  9. BAG2 was directly phosphorylated at serine 20 in vitro by MAPKAPK2 (zeige MAPKAPK2 Antikörper) and MAPKAP2 is also required for phosphorylation of BAG2 in vivo.

  10. BAG2 binds to the carboxyl terminus of Hsp70-interacting protein (CHIP) and provides a cochaperone-dependent regulatory mechanism for preventing unregulated ubiquitylation of misfolded proteins by CHIP

Mouse (Murine) BCL2-Associated Athanogene 2 (BAG2) Interaktionspartner

  1. findings support the notion that BAG2 is an upstream regulator of the PINK1 (zeige PINK1 Antikörper)/PARKIN (zeige PARK2 Antikörper) signaling pathway.

  2. Native Bag2-NTD crystals diffracted to 2.27 A resolution and belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 75.5, b = 84.7, c = 114.1 A

  3. Free and Hsc70 (zeige HSPA8 Antikörper)-bound crystal structures of Bag2-BNB show its dimeric structure, in which a flanking linker helix and loop bind to Hsc70 (zeige HSPA8 Antikörper) to promote nucleotide exchange.

BAG2 Antigen-Profil

Protein Überblick

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Genbezeichner und Symbole assoziert mit BAG2

  • BCL2 associated athanogene 2 (bag2) Antikörper
  • BCL2 associated athanogene 2 (BAG2) Antikörper
  • BCL-2-associated athanogene 2 (BAG2) Antikörper
  • BCL2-associated athanogene 2 (bag2) Antikörper
  • BCL2-associated athanogene 2 (Bag2) Antikörper
  • Bcl2-associated athanogene 2 (Bag2) Antikörper
  • 2610042A13Rik Antikörper
  • ATBAG2 Antikörper
  • BAG-2 Antikörper
  • BAG2 Antikörper
  • BC016230 Antikörper
  • BCL-2-associated athanogene 2 Antikörper
  • dJ417I1.2 Antikörper
  • MGC89300 Antikörper
  • MTG10.13 Antikörper
  • MTG10_13 Antikörper
  • zgc:64195 Antikörper

Bezeichner auf Proteinebene für BAG2

BCL2-associated athanogene 2 , BAG family molecular chaperone regulator 2 , putative BCL2-associated athanogene 2 , BAG-family molecular chaperone regulator-2 , bcl-2-associated athanogene 2 , dJ417I1.2 (BAG-family molecular chaperone regulator 2) , BAG-2

GENE ID SPEZIES
448388 Xenopus (Silurana) tropicalis
462797 Pan troglodytes
100346462 Oryctolagus cuniculus
100190641 Taeniopygia guttata
836330 Arabidopsis thaliana
9532 Homo sapiens
393975 Danio rerio
421880 Gallus gallus
610506 Canis lupus familiaris
506107 Bos taurus
213539 Mus musculus
690038 Rattus norvegicus
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