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The protein encoded by BAG5 is a member of the BAG1-related protein family. Zusätzlich bieten wir Ihnen BAG5 Antikörper (152) und BAG5 Proteine (12) und viele weitere Produktgruppen zu diesem Protein an.
Subsequent BAG5 upregulation ameliorated the tumor-suppressive effects of miR (zeige MLXIP ELISA Kits)-127-3p overexpression in epithelial ovarian cancer (EOC). In conclusion, miR (zeige MLXIP ELISA Kits)-127-3p functions as a tumor suppressor in EOC, and its influence on EOC is directly through regulation of BAG5.
High BAG5 expression is associated with pancreatic cancer.
This study showed that BAG2 (zeige BAG2 ELISA Kits) (Bcl-2 (zeige BCL2 ELISA Kits) associated athanogene family protein 2) and BAG5 (Bcl-2 (zeige BCL2 ELISA Kits)-associated athanogene family protein 5 (zeige CAPS ELISA Kits)) stabilise pathogenic ataxin3-80Q by inhibiting its ubiquitination.
BAG5 protects against mitochondrial oxidative damage through regulating PINK1 degradation.
BAG5 is a binding partners of LRRK2 (zeige LRRK2 ELISA Kits) and part of a complex that promotes clearance of Golgi-derived vesicles through the autophagy-lysosome system.
Bag5 is overexpressed in prostate cancer and plays a role in endoplamic reticulum-stress induced apoptosis. Furthermore we have identified GRP78/BiP (zeige HSPA5 ELISA Kits) as a novel interaction partner of Bag5.
BAG5 directly interacts with Parkin and stabilizes Parkin via the ubiquitin-mediated proteasomal pathway.
A novel function for BAG5 as a modulator of CHIP E3 ubiquitin ligase activity with implications for CHIP-mediated regulation of alpha-syn oligomerization.
We replicated the association of BCL2L11 (zeige BCL2L11 ELISA Kits) and CASP9 (zeige CASP9 ELISA Kits) with non-Hodgkin's lymphoma risk at the gene and SNP level, and identified novel associations with BCLAF1 (zeige BCLAF1 ELISA Kits) and BAG5.
Bcl-2-associated athanogene 5 (BAG5) is a negative regulator of both Hsp70 and parkin function that sensitizes dopaminergic neurons to injury-induced death.
knockdown of Bag5 exacerbated Abeta1-42-induced apoptosis.
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene.
BAG family molecular chaperone regulator 5
, BAG-family molecular chaperone regulator-5
, bcl-2-associated athanogene 5
, BCL2-associated athanogene 5
, BAG-family molecular chaperone regulator-5 (BAG-5)
, BAG family molecular chaperone regulator 5-like