anti-Ataxin 2-Binding Protein 1 (A2BP1) Antikörper

The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Zusätzlich bieten wir Ihnen Ataxin 2-Binding Protein 1 Proteine (9) und Ataxin 2-Binding Protein 1 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
A2BP1 54715 Q9NWB1
A2BP1 268859 Q9JJ43
A2BP1 302920  
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Showing 10 out of 97 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-A2BP1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Human brain 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit <br /> Target Name: Rbfox1 <br /> Sample Tissue: Mouse Testis lysates <br /> Antibody Dilution: 1.0 µg/mL 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-A2BP1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>MCF7 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-A2BP1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>HepG2 cell lysate WB Suggested Anti-A2BP1 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 <br /> Positive Control: HepG2 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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REACT_Chlamydomonas reinhardtii Kaninchen Unkonjugiert IF, WB   200 μL Anmelden zum Anzeigen 2 bis 4 Tage
401,50 €
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Human Maus Unkonjugiert ICC, IF, IHC, WB Western blot of mouse brain homogenates stained with MCA-Fox1. Antibody binds closely spaced 48 kDa and 46 kDa bands. Rat brain neural cultures stained with ABIN1580418 (green), rabbit polyclonal antibody to NF-M RPCA-NF-M (red) and DNA (blue). The ABIN1580418 antibody reveals nuclear and distal cytoplasmic staining for Fox1, and the complete absence of staining of non-neuronal cells. 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
235,71 €
Details
Rind (Kuh) Maus Unkonjugiert ICC, IF, WB Western Blot: A2BP1 Antibody (1G10) [NBP2-25141] - Mouse brain homogenates. Antibody binds closely spaced 48kDa and 46kDa bands. Immunocytochemistry/Immunofluorescence: A2BP1 Antibody (1G10) [NBP2-25141] - Rat brain neural cultures stained with NBP2-25141 (green), rabbit polyclonal antibody to NF-M: ABIN4277055 (red) and DNA (blue). The NBP2-25141 antibody reveals nuclear and distal cytoplasmic staining for A2BP1 and the complete absence of staining of non-neuronal cells. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
291,00 €
Details
Human Maus Unkonjugiert ICC, IF, IHC, IHC (p), IP, SimWes, WB Immunocytochemistry/Immunofluorescence: A2BP1 Antibody (D8H8) [NBP2-13169] - A2BP1 antibody was tested in Neuro-2a cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). Western Blot: A2BP1 Antibody (D8H8) [NBP2-13169] - Western blot analysis of A2BP1 expression in 1) human brain and 2) mouse brain tissue lysates. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
459,65 €
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A2BP1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-Ataxin 2-Binding Protein 1 Antikörper

  1. Chlamydomonas reinhardtii (C. reinhardtii) Polyclonal A2BP1 Primary Antibody für IF, WB - ABIN108467 : Terauchi, Peers, Kobayashi, Niyogi, Merchant: Trophic status of Chlamydomonas reinhardtii influences the impact of iron deficiency on photosynthesis. in Photosynthesis research 2010 (PubMed)
    Show all 3 Pubmed References

  2. Cow (Bovine) Polyclonal A2BP1 Primary Antibody für WB - ABIN2779139 : Fogel, Wexler, Wahnich, Friedrich, Vijayendran, Gao, Parikshak, Konopka, Geschwind: RBFOX1 regulates both splicing and transcriptional networks in human neuronal development. in Human molecular genetics 2012 (PubMed)

Weitere Antikörper gegen Ataxin 2-Binding Protein 1 Interaktionspartner

Zebrafish Ataxin 2-Binding Protein 1 (A2BP1) Interaktionspartner

  1. This study underlines that tightly regulated splicing is necessary for unconstrained cardiac function and renders the splicing regulator (zeige PTBP2 Antikörper) rbfox1 an interesting target for investigation in human heart failure and cardiomyopathy.

Chlamydomonas reinhardtii (C. reinhardtii) Ataxin 2-Binding Protein 1 (A2BP1) Interaktionspartner

  1. When the abundance of the FOX1 gene product is reduced, Chlamydomonas cells grow poorly in iron-deficient medium, but not in iron-replete medium, suggesting that FOX1-dependent iron uptake is a high-affinity pathway.

Human Ataxin 2-Binding Protein 1 (A2BP1) Interaktionspartner

  1. Report a 1.8 A X-ray structure of the free Fox-1 containing six distinct monomers. We use this and the nuclear magnetic resonance (NMR) structure of the Fox-1 protein/RNA complex for molecular dynamics (MD) analyses of the structured hydration. The individual monomers of the X-ray structure show diverse hydration patterns, however, MD excellently reproduces the most occupied hydration sites.

  2. Copy-number variations are enriched for RBFOX1 and other neurodevelopmental genes in children with developmental coordination disorder.

  3. We present a joint atomistic molecular dynamics (MD) and experimental study of two RRM-containing proteins bound with their single-stranded target RNAs, namely the Fox-1 and SRSF1 (zeige SRSF1 Antikörper) complexes.The simulations predict unanticipated specific participation of Arg142 at the protein-RNA interface of the SRFS1 complex, which is subsequently confirmed by NMR and ITC measurements

  4. FGF12 (zeige FGF12 Antikörper), RBFOX1, and MIR302F could be important in human heterotaxy, because they were noted in multiple cases. Further investigation into genes involved in the NODAL, BMP, and WNT (zeige WNT2 Antikörper) body patterning pathways and into the dosage effects of FGF12 (zeige FGF12 Antikörper), RBFOX1, and MIR302F is warranted.

  5. Data indicate that multiple rare, coding variants in RBFOX1 protein associated with reduced systolic blood pressure (SBP (zeige SHBG Antikörper)).

  6. study identifies regulation of RNA splicing by RBFox1 as an important player in transcriptome reprogramming during heart failure that influence pathogenesis of the disease

  7. The SNP rs1478697 in A2BP1 may be associated with antipsychotic induced weight gain induced by 8-week treatment with olanzapine.

  8. This study underlines that tightly regulated splicing is necessary for unconstrained cardiac function and renders the splicing regulator (zeige PTBP2 Antikörper) rbfox1 an interesting target for investigation in human heart failure and cardiomyopathy.

  9. Cytoplasmic Rbfox1 target mRNAs were enriched in genes involved in cortical development and autism

  10. The Genome-wide association study showed a significant association for a variant within the RBFOX1 gene with generalized anxiety disorder.

Mouse (Murine) Ataxin 2-Binding Protein 1 (A2BP1) Interaktionspartner

  1. Upon picrotoxin treatment, Rbfox1 expression was downregulated by miR (zeige MLXIP Antikörper)-129-5p, thereby allowing the repression of Atp2b4 (zeige ATP2B4 Antikörper) and Dcx (zeige DCX Antikörper).

  2. Cytoplasmic Rbfox1 target mRNAs were enriched in genes involved in cortical development and autism

  3. Gain- and loss-of-function experiments demonstrated that Rbfox1 and Rbfox2 (zeige RBM9 Antikörper) cooperate in promoting Mef2D (zeige MEF2D Antikörper) splicing and subsequent myogenesis.

  4. Rbfox1 regulates RNA splicing required for skeletal muscle structure and function.

  5. Fox-1, expressed specifically in the neural cell stage, promoted Mef2c (zeige MEF2C Antikörper) exon beta inclusion via the GCAUG.

  6. The results suggest that in neuronal tissues A2BP1 plays important roles, which are regulated in a spatiotemporal manner.

  7. our results suggest that a component of FSHD pathogenesis may arise by over-expression of FRG1 (zeige FRG1 Antikörper), reducing Rbfox1 levels and leading to aberrant expression of an altered Calpain 3 (zeige CAPN3 Antikörper) protein through dysregulated splicing

  8. Fox-1 splices mRNAs encoding proteins important in synaptic transmission and membrane excitation.

  9. The splicing regulator (zeige PTBP2 Antikörper) Rbfox1 controls neuronal excitation in the mammalian brain.

  10. These data indicate that A2BP1 mutations may clinically affect very selective forebrain neuron types from early periods of development.

Ataxin 2-Binding Protein 1 (A2BP1) Antigen-Profil

Protein Überblick

The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit A2BP1

  • RNA binding protein, fox-1 homolog (C. elegans) 1 (RBFOX1) Antikörper
  • ataxin 2-binding protein 1 (LOC453899) Antikörper
  • ataxin 2-binding protein 1 (LOC100357475) Antikörper
  • RNA binding protein, fox-1 homolog (C. elegans) 1 (rbfox1) Antikörper
  • multicopper ferroxidase (FOX1) Antikörper
  • RNA binding protein, fox-1 homolog (C. elegans) 1 (Rbfox1) Antikörper
  • 2BP1 Antikörper
  • A2bp Antikörper
  • A2bp1 Antikörper
  • fox-1 Antikörper
  • FOX1 Antikörper
  • Hrnbp1 Antikörper
  • zgc:103635 Antikörper

Bezeichner auf Proteinebene für A2BP1

RNA binding protein, fox-1 homolog (C. elegans) 1 , ataxin 2-binding protein 1 , RNA binding protein fox-1 homolog 1 , ataxin-2-binding protein 1 , fox-1 homolog A , hexaribonucleotide-binding protein 1 , ataxin 2 binding protein 1 , hexaribonucleotide binding protein 1 , RNA binding protein, fox-1 homolog 1

GENE ID SPEZIES
416645 Gallus gallus
453899 Pan troglodytes
100357475 Oryctolagus cuniculus
449554 Danio rerio
5720109 Chlamydomonas reinhardtii
54715 Homo sapiens
521304 Bos taurus
268859 Mus musculus
302920 Rattus norvegicus
100172936 Pongo abelii
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