anti-Asporin (ASPN) Antikörper

ASPN encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. Zusätzlich bieten wir Ihnen Asporin Kits (38) und Asporin Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ASPN 54829 Q9BXN1
ASPN 66695 Q99MQ4
ASPN 306805  
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Top anti-Asporin Antikörper auf antikoerper-online.de

Showing 10 out of 49 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert ELISA, WB ABIN185364 (0.3µg/ml) staining of Human Bone Marrow lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN185364 staining of ATDC5 cells (Panels A and C) and DAPI (panels B and D). Data gratefuly received from Dr. Shiro Ikegawa, SNP Research Center, RIKEN, Japan. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-ASPN Antibody Titration: </b>2.5ug/ml<br><b>Positive Control: </b>HepG2 cell lysate Host: Rabbit <br /> Target Name: ASPN <br /> Sample Tissue: HepG2Lane A:  Primary Antibody Lane B:  Primary Antibody + Blocking Peptide <br />Primary Antibody Concentration: 2.5 µg/mL Peptide Concentration:..0 µg/mL Lysate Quantity:.41 µg/laneGel Concentration: 12 % 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB Western blot analysis of ASPN antibody (Center) (ABIN390536) in HL60 cell line lysates(35 µg/lane). ASPN (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma with ASPN Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert ICC, IF, WB Immunocytochemistry/Immunofluorescence: Asporin Antibody [NBP2-15492] - Immunofluorescence analysis of methanol-fixed HeLa, using antibody at 1:200 dilution. Western Blot: Asporin Antibody [NBP2-15492] - Sample (30 ug of whole cell lysate) A: HCT116 10% SDS PAGE gel, diluted at 1:1000. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$514.63
Details
Human Ziege Unkonjugiert ICC, IF, ELISA, WB ABIN250383 (0.3µg/ml) staining of Human Bone Marrow lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN250383 staining of ATDC5 cells (Panels A and C) and DAPI (panels B and D). Data gratefuly received from Dr. Shiro Ikegawa, SNP Research Center, RIKEN, Japan. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Ziege Unkonjugiert EIA, IF, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$455.40
Details
Human Kaninchen Unkonjugiert ICC, IF, WB ICC/IF Image Immunofluorescence analysis of methanol-fixed HeLa, using Asporin, antibody at 1:200 dilution. WB Image Asporin antibody [N3C1], Internal detects Asporin protein by western blot analysis. A. 30 μg A549 whole cell lysate/extract B. 30 μg H1299 whole cell lysate/extract C. 30 μg HCT116 whole cell lysate/extract 10 % SDS-PAGE Asporin antibody [N3C1], Internal , dilution: 1:1000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Ziege Unkonjugiert IF, ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details
Hund Kaninchen Unkonjugiert IHC (p), WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Human Ziege Unkonjugiert ICC, ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details

ASPN Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human ,
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, , , , ,
Mouse (Murine)
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Rat (Rattus)
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Am meisten referenzierte anti-Asporin Antikörper

  1. Human Polyclonal Asporin Primary Antibody für ICC, IF - ABIN250383 : Yang, Nyalwidhe, Guo, Drake, Semmes: Targeted identification of metastasis-associated cell-surface sialoglycoproteins in prostate cancer. in Molecular & cellular proteomics : MCP 2011 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal Asporin Primary Antibody für ICC, IF - ABIN4281912 : Murphy, Dowling, Zweyer, Mundegar, Henry, Meleady, Swandulla, Ohlendieck: Proteomic analysis of dystrophin deficiency and associated changes in the aged mdx-4cv heart model of dystrophinopathy-related cardiomyopathy. in Journal of proteomics 2016 (PubMed)

Weitere Antikörper gegen Asporin Interaktionspartner

Human Asporin (ASPN) Interaktionspartner

  1. Asporin promotes epithelial mesenchymal transformation, invasion, and migration of pancreatic cancer cellss by activating CD44 (zeige CD44 Antikörper)-AKT (zeige AKT1 Antikörper)/ERK (zeige EPHB2 Antikörper)-NF-kappaB (zeige NFKB1 Antikörper) pathway in paracrine and autocrine manner.

  2. High ASPN expression in stroma is associated with prostate cancer progression.

  3. To test the associations of ASPN variations with risk of subsequent oncologic outcomes.

  4. Collectively, our findings indicate that ASPN is upregulated and plays an oncogenic role in gastric cancer progression and metastasis by influencing the EGFR (zeige EGFR Antikörper) signaling pathway.

  5. Our results showed that ASPN rs13301537 T to C change and variant C genotype may contribute to knee OA risk in a Chinese Han population.

  6. this is the first case-control study in Mexican women that suggests that menopause and the D-repeat polymorphism in the ASPN gene are associated with knee OA

  7. Osteomodulin (zeige OMD Antikörper), osteoglycin (zeige OGN Antikörper), and asporin appear to be distinctly regulated in osteoarthritis labrum compared to OA cartilage.

  8. Asporin may represent a new therapeutic target molecule for the development of drugs aimed at manipulating the cancer microenvironment.

  9. This meta-analysis shows that the ASPN D14, D13, and D15 (zeige MRPL16 Antikörper) alleles are not associated with the development of osteoarthritis in Europeans and Asians. [Meta-Analysis]

  10. A meta-analysis suggest that the D-repeat of asporin gene (ASPN) may not be a major susceptibility locus in the Caucasian and Asian populations with knee osteoarthritis.

Mouse (Murine) Asporin (ASPN) Interaktionspartner

  1. Asporin deficiency changes skin glycosaminoglycan composition, and decorin (zeige DCN Antikörper) and biglycan (zeige BGN Antikörper) content, which may explain the changes in skin mechanical properties.

  2. inhibition of TLR2 (zeige TLR2 Antikörper)- and TLR4 (zeige TLR4 Antikörper)-induced inflammatory responses and binding abilities to TLR2 (zeige TLR2 Antikörper) and TLR4 (zeige TLR4 Antikörper)

  3. positively regulates FGF-2 (zeige FGF2 Antikörper) activity through a direct interaction

  4. Findings suggest that asporin is one of the important cartilage matrix proteins that binds to the ECM (zeige MMRN1 Antikörper) and TGF-beta1 (zeige TGFB1 Antikörper) and thereby modulates interactions between TGF-beta (zeige TGFB1 Antikörper) and its signaling receptors.

  5. PLAP-1/asporin plays a specific role in the periodontal ligament as a negative regulator of cytodifferentiation and mineralization by regulating BMP-2 (zeige BMP2 Antikörper) activity to prevent the periodontal ligament from developing non-physiological mineralization

  6. The findings indicate that TGF-beta1 (zeige TGFB1 Antikörper) induces ASPN through Smad3 (zeige SMAD3 Antikörper) but that this induction is indirect.

  7. Leucine-rich repeat motif 5 (LRR5) of PLAP-1/asporin, plays an important role in the PLAP-1/asporin-BMP-2 (zeige BMP2 Antikörper) interaction.

Xenopus laevis Asporin (ASPN) Interaktionspartner

  1. The small leucine-rich repeat secreted protein Asporin induces eyes in Xenopus embryos through the IGF signalling pathway.

Pig (Porcine) Asporin (ASPN) Interaktionspartner

  1. Mapping of the OGN (zeige OGN Antikörper) and ASPN genes and association with growth and carcass traits.

Asporin (ASPN) Antigen-Profil

Protein Überblick

This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis. Alternate splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit anti-Asporin (ASPN) Antikörper

  • asporin (ASPN) Antikörper
  • asporin (LRR class 1) (aspn) Antikörper
  • asporin (Aspn) Antikörper
  • asporin L homeolog (aspn.L) Antikörper
  • 4631401G09Rik Antikörper
  • AA986886 Antikörper
  • aspnl Antikörper
  • bgl3 Antikörper
  • os3 Antikörper
  • plap-1 Antikörper
  • plap1 Antikörper
  • slrr1c Antikörper
  • wu:fk08c11 Antikörper
  • zgc:109936 Antikörper

Bezeichner auf Proteinebene für anti-Asporin (ASPN) Antikörper

asporin (LRR class 1) , asporin proteoglycan , periodontal ligament associated protein 1 , small leucine-rich protein 1C , asporin , biglycan-like protein 3 , periodontal ligament-associated protein 1

GENE ID SPEZIES
54829 Homo sapiens
65228 Danio rerio
66695 Mus musculus
306805 Rattus norvegicus
415954 Gallus gallus
495030 Xenopus laevis
507990 Bos taurus
610685 Canis lupus familiaris
739953 Pan troglodytes
100054817 Equus caballus
100410747 Callithrix jacchus
100446487 Pongo abelii
100600227 Nomascus leucogenys
100732832 Cavia porcellus
100511749 Sus scrofa
101108885 Ovis aries
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