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an L-asparaginase possibly involved in astroglial production of neuroactive S-aspartate. Zusätzlich bieten wir Ihnen Asparaginase Like 1 Antikörper (75) und Asparaginase Like 1 Kits (12) und viele weitere Produktgruppen zu diesem Protein an.
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Our studies suggest that the p.G178R mutation in ASRGL1 leads to photoreceptor degeneration resulting in progressive vision loss.
Multiple negatively charged small molecules interact within the active site of ASRGL1 to act as a base in promoting cleavage.
Reduced expression of ASRGL1, defined as <75% positively stained tumor cells, was significantly associated with poor prognosis and reduced disease-specific survival in endometrioid endometrial adenocarcinoma (EEA).
Human ALP (zeige ALP Proteine) cDNA was subsequently cloned. It showed 77% identity to the rat ALP (zeige ALP Proteine) sequence and the gene, ASRGL1 (asparaginase-like 1), mapped to chromosome locus 11q12.3.
ASRGL1 exhibits beta-aspartyl peptidase activity consistent with plant-type asparaginases. ASRGL1 is shown to be an Ntn (zeige NRTN Proteine) hydrolase for which Thr168 serves as the essential N-terminal nucleophile for intramolecular processing and catalysis.
an L-asparaginase possibly involved in astroglial production of neuroactive S-aspartate
asparaginase like 1
, asparaginase-like 1 protein
, L-asparagine amidohydrolase
, asparaginase-like protein 1
, isoaspartyl dipeptidase
, isoaspartyl peptidase/L-asparaginase
, asparaginase-like 1
, asparaginase-like sperm autoantigen
, glial asparaginase