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Ash1 (Absent, Small, Or Homeotic)-like Proteine (ASH1L)

ASH1L encodes a member of the trithorax group of transcriptional activators. Zusätzlich bieten wir Ihnen ASH1L Antikörper (40) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte ASH1L ASH1L 310638  
ASH1L 55870 Q9NR48
Maus ASH1L ASH1L 192195 Q99MY8
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
HOST_Escherichia coli (E. coli) Human His tag,DYKDDDDK Tag Recombinant ASH1L (2407-2579) protein gel. ASH1L (2407-2579) protein was run on a 10% SDS-PAGE gel and stained with Coomassie blue. 100 μg Anmelden zum Anzeigen 1 bis 3 Tage
469,44 €
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ASH1L Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
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Weitere Proteine zu Ash1 (Absent, Small, Or Homeotic)-like (ASH1L) Interaktionspartnern

Human Ash1 (Absent, Small, Or Homeotic)-like (ASH1L) Interaktionspartner

  1. Our data suggest a role for ASH1L, a methyl transferase protein and member of the trithorax (zeige MLLT1 Proteine) (Trx (zeige VAC14 Proteine)) family, in regulation of the HBB (zeige HBB Proteine) gene and as a potential modifier of beta-thalassaemia severity.

  2. Structural features were identified in ASH1L related to its' function and enzymatic activity.

  3. Both ASH1L and SETD2 are H3K36 specific methyltransferases but only SETD2 can trimethylate this mark.

  4. These data demonstrate that miR (zeige MLXIP Proteine)-142-3p downregulation has a role in thyroid tumorigenesis, by regulating ASH1L and MLL1.

  5. Our results uncover a novel regulatory cascade orchestrated by Ash1l with RAR (zeige RARA Proteine) and provide insights into mechanisms underlying the establishment of the transcriptional activation that counteracts Polycomb (zeige CBX2 Proteine) silencing

  6. all of the H3K36-specific methyltransferases, including ASH1L, HYPB, NSD1, and NSD2 (zeige WHSC1 Proteine) were inhibited by ubH2A, whereas the other histone methyltransferases, including PRC2, G9a (zeige EHMT2 Proteine), and Pr-Set7 (zeige SETD8 Proteine) were not affected by ubH2A.

  7. induction of Cdk5 (zeige CDK5 Proteine) activity is a novel mechanism through which hASH1 (zeige ASCL1 Proteine) may regulate migration in lung carcinogenesis

  8. Long Non-coding RNA, DBE-T recruits the Trithorax (zeige MLLT1 Proteine) group protein Ash1L to the FSHD locus, driving histone H3 (zeige HIST3H3 Proteine) lysine 36 dimethylation, chromatin remodeling, and 4q35 gene transcription.

  9. ASH1 (zeige ASCL1 Proteine) and MLL1 synergize in activation of Hox (zeige MSH2 Proteine) genes.

  10. human ASH1L specifically methylates histone H3 (zeige HIST3H3 Proteine) Lys (zeige LYZ Proteine)-36.

Mouse (Murine) Ash1 (Absent, Small, Or Homeotic)-like (ASH1L) Interaktionspartner

  1. Histone Methyltransferase Ash1l Is a Target of miR (zeige MLXIP Proteine)-291 and Regulates Hox (zeige MSH2 Proteine) Gene Expression.

  2. Ash1l is a novel key regulator of changes associated with the adaptation of HSCs to the BM niche at the fetal to adult transition or upon transplantation of HSCs into an adult recipient.

  3. all of the H3K36-specific methyltransferases, including ASH1L, HYPB, NSD1, and NSD2 (zeige WHSC1 Proteine) were inhibited by ubH2A, whereas the other histone methyltransferases, including PRC2, G9a (zeige EHMT2 Proteine), and Pr-Set7 (zeige SETD8 Proteine) were not affected by ubH2A.

  4. Ash1l-mediated H3K4 methylation at the Tnfaip3 (zeige TNFAIP3 Proteine) promoter is required for controlling innate IL-6 (zeige IL6 Proteine) production and suppressing inflammatory autoimmune diseases, providing mechanistic insight into epigenetic modulation of immune responses and inflammation

  5. ASH1 (zeige ASCL1 Proteine) mono- or di-methylates histone H3 (zeige HIST3H3 Proteine) K36 (zeige KRT36 Proteine) but not any other lysine residues of recombinant unmodified mammalian histones

  6. the C-terminal part of ASH1 (zeige ASCL1 Proteine) interacts with HDAC1 (zeige HDAC1 Proteine) repression complexes, suggesting that the PHD (zeige PDC Proteine) finger of ASH1 (zeige ASCL1 Proteine) may be involved in down-regulation of genes for normal development of alphabeta T cells.

ASH1L Protein Überblick

Protein Überblick

This gene encodes a member of the trithorax group of transcriptional activators. The protein contains four AT hooks, a SET domain, a PHD-finger motif, and a bromodomain. It is localized to many small speckles in the nucleus, and also to cell-cell tight junctions.

Genbezeichner und Symbole assoziert mit ASH1L

  • ash1 (absent, small, or homeotic)-like (Drosophila) (Ash1l)
  • ash1 (absent, small, or homeotic)-like (Drosophila) (ASH1L)
  • ash1 (absent, small, or homeotic)-like (Drosophila) (ash1l)
  • absent, small, or homeotic discs 1 homolog (ash1l)
  • Ash1l protein (CpipJ_CPIJ001203)
  • 8030453L17Rik Protein
  • Ash1 Protein
  • ASH1L Protein
  • ASH1L1 Protein
  • Ci-ZF(PHD)-13 Protein
  • DKFZp468L0923 Protein
  • E430018P19Rik Protein
  • fi34d11 Protein
  • Kmt2h Protein
  • si:ch211-81a5.3 Protein
  • wu:fi34d11 Protein

Bezeichner auf Proteinebene für ASH1L

probable histone-lysine N-methyltransferase ASH1L , ash1 (absent, small, or homeotic)-like (Drosophila) , zinc finger (PHD)-13 , Ash1l protein , absent, small, or homeotic 1-like , ASH1-like protein , absent small and homeotic disks protein 1 homolog , histone-lysine N-methyltransferase ASH1L , lysine N-methyltransferase 2H , absent, small, or homeotic discs 1 , chromatin remodeling factor

GENE ID SPEZIES
310638 Rattus norvegicus
425064 Gallus gallus
480128 Canis lupus familiaris
540563 Bos taurus
457370 Pan troglodytes
563799 Danio rerio
778906 Ciona intestinalis
6032233 Culex quinquefasciatus
100017118 Monodelphis domestica
100057386 Equus caballus
100174377 Pongo abelii
100354541 Oryctolagus cuniculus
55870 Homo sapiens
192195 Mus musculus
Ausgewählte Anbieter für ASH1L Proteine (ASH1L)
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