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The protein encoded by AIP is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. Zusätzlich bieten wir Ihnen AIP Antikörper (97) und AIP Kits (18) und viele weitere Produktgruppen zu diesem Protein an.
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Human AIP Protein expressed in Escherichia coli (E. coli) - ABIN667502
Kazlauskas, Poellinger, Pongratz: The immunophilin-like protein XAP2 regulates ubiquitination and subcellular localization of the dioxin receptor. in The Journal of biological chemistry 2001
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The prevalence of AIP mutations in young Mexican patients with acromegaly is similar to that of European cohorts.
Case Report: truncating AIP mutation, p.W279*, in father/daughter presenting with familial isolated pituitary adenoma.
A modest relationship was found between PPARalpha (zeige PPARA Proteine) and AIP expression, both being significantly higher in the presence of pre-operative somatostatin (zeige SST Proteine) analogues in somatotropinoma patients.
The prevalence of AIP(mut (zeige MUT Proteine)) in Turkish patients was found to be 1 % in sporadic acromegaly in the present study.
No digenism with AIP was identified among patients with sporadic pituitary adenomas.
The aim of this study was to examine mutations in the aryl hydrocarbon receptor-interacting protein (AIP) gene
AIP mutations are associated with pituitary gigantism.
in a family of a patient with gigantism, identified a new AIP germline mutation (c.685C>T, p.Q229X) predicted to produce a truncated AIP protein, lacking its biological properties due to the disruption of the C-terminus binding sites for both the chaperones and the client proteins of AIP
a small angle X-ray scattering-derived solution structure of aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1 (zeige AIPL1 Proteine)) and functional properties of disease-linked AIPL1 (zeige AIPL1 Proteine)-proline-rich domain mutants
traces the current state of knowledge regarding the clinical features of FIPA and the particular genetic, pathologic, and clinical characteristics of pituitary adenomas due to AIP mutations [review]
Results demonstrated that Aip inactivation promoted somatotroph tumorigenesis and overproduction of growth hormone (zeige GH1 Proteine) probably through increased Stat3 (zeige STAT3 Proteine) activation.
Results provide novel evidence that AIP has an important role in the regulation of cAMP synthesis.
XAP2 exerts a negative effect on ERalpha (zeige ESR1 Proteine) transcriptional activity and may thus prevent ERalpha (zeige ESR1 Proteine)-dependent events.
Developmental control of apoptosis by the immunophilin (zeige FKBP1A Proteine) aryl hydrocarbon receptor-interacting protein (AIP) involves mitochondrial import of the survivin (zeige BIRC5 Proteine) protein
Mice with inactivation of aryl hydrocarbon receptor-interacting protein display complete penetrance of pituitary adenomas with aberrant ARNT (zeige ARNT Proteine) expression.
Data show that AIP is not required for the induction of the Cyp1a1 (zeige CYP1A1 Proteine) and Cyp1a2 (zeige CYP1A1 Proteine) genes.
XAP2 hinders importin beta (zeige KPNB1 Proteine) binding to the mAhR complex and represses the transactivation potential of the AhR (zeige AHR Proteine) by stabilizing the receptor complex and/or blocking nucleocytoplasmic shuttling of the AhR (zeige AHR Proteine) complex
PPARalpha (zeige PPARA Proteine) is in a complex with hsp90 (zeige HSP90 Proteine) and XAP2, and XAP2 appears to function as a repressor
XAP2 has a role in stabilization of the dioxin receptor (zeige AHR Proteine)
The role of Xap2 and C-terminal hsp-70 (zeige HSP70 Proteine) interacting protein on the endogenous Ah receptors expressed in mouse cell lines was determined.
The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus.
aryl hydrocarbon receptor interacting protein
, AH receptor-interacting protein-like
, AH receptor-interacting protein
, HBV X-associated protein 2
, immunophilin homolog ARA9
, aryl-hydrocarbon receptor-interacting protein
, HBV-X associated protein
, immunophilin XAP2