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GTPase-activating protein. Zusätzlich bieten wir Ihnen AGAP1 Antikörper (37) und AGAP1 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
The effect of AGAP1 Knockdown could be rescued by FLAG-AGAP1, but not by an AGAP1 mutant that did not bind Kif2A (zeige KIF2A ELISA Kits) efficiently, ArfGAP1 (zeige ARFGAP3 ELISA Kits)-HA or Kif2A (zeige KIF2A ELISA Kits)-GFP. The results support the hypothesis that the Kif2A.AGAP1 complex contributes to control of cytoskeleton remodeling involved in cell movement.
GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.
overexpression inhibited formation of platelet-derived growth factor-induced ruffles and also induced loss of actin stress fibers
AGAP1 is a novel binding partner of nitric oxide-sensitive guanylyl cyclase
CENTG2 is an intriguing candidate gene that merits further scrutiny for its role in autism.
The AGAP1 has been found to associate with the adaptor protein complex AP-3 and regulate the function of AP-3 endosomes.
AGAP1 is unique among the AZAPs in its specificity for Arf1 (zeige ARF1 ELISA Kits), and this activity is dependent on its NH(2)-terminal GTPase (zeige RACGAP1 ELISA Kits)-like domain. AGAP1 induce reciprocal activation of Arf6 (zeige ARF6 ELISA Kits).
GTP-binding protein (zeige DRG1 ELISA Kits)-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.
The elimination of adaptor protein 3 (zeige HSPB3 ELISA Kits) or abrogation of AGAP1-M5 muscarinic receptor (zeige CHRM5 ELISA Kits) interaction in vivo decreased the magnitude of presynaptic M5 muscarinic receptor (zeige CHRM5 ELISA Kits) mediated dopamine release potentiation in the striatum.
GTPase-activating protein. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system (By similarity).
centaurin, gamma 2
, centaurin, gamma 3
, arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1
, ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
, ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
, arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1-like
, centaurin, gamma 2-like
, Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 1
, GTP-binding and GTPase-activating protein 1