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The protein encoded by ASB10 is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. Zusätzlich bieten wir Ihnen Ankyrin Repeat and SOCS Box-Containing 10 Kits (9) und Ankyrin Repeat and SOCS Box-Containing 10 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.
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ASB10 may play a role in ubiquitin-mediated degradation pathways in tabecular meshwork cells.
non-synonymous mutations in ASB10 do not cause Mendelian forms of primary open angle glaucoma
Variants in ASB10 are associated with open-angle glaucoma.
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. The SOCS box serves to couple suppressor of cytokine signaling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene.
ankyrin repeat and SOCS box protein 10
, ankyrin repeat and SOCS box-containing 10
, ankyrin repeat and SOCS box protein 10-like
, ankyrin repeat and SOCS box-containing protein 10